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17,054 grants matching genome editing

Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides

$691,279
Paul B McCray · University Of Iowa · UG3 · FY2020 · HL

Integrated Multiscale Networks in Schizophrenia

$691,233
Eric E Schadt · Icahn School Of Medicine At Mount Sinai · R01 · FY2020 · MH

Clinical and genetic risk factors associated with adverse long-term health outcomes after curative therapies in individuals with sickle cell disease

$691,115
Michael Rutledge Debaun · Vanderbilt University Medical Center · U01 · FY2021 · HL

The role of mechanosensing and mechanotransduction in joint homeostasis and osteoarthritis susceptibility

$691,089
Michael J Jurynec · Utah State Higher Education System--University Of Utah · R01 · FY2025 · AR

Project 2: Genes required for dendritic cell responses to pathogens and T cells

$690,783
Nir Hacohen · Harvard Medical School · U19 · FY2021 · AI

In vivo delivery of CRISPR Cas9-guide RNA nucleoprotein complexes using the nanoPOD platform

$690,751
John Christian Tilton · Case Western Reserve University · UG3 · FY2019 · HL

Regulation of hematopoiesis by ribosomal protein paralogs

$690,669
David L Wiest · Research Inst Of Fox Chase Can Ctr · R37 · FY2025 · AI

Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy

$690,558
Joseph C Wu · Stanford University · R01 · FY2023 · HL

Scalable platform for optimizing human cardiac tissue engineering via optical pacing and on-demand oxygenation

$690,516
Emilia Entcheva · George Washington University · R01 · FY2021 · HL

Genetic and physiologic regulation of pig islet development and function

$690,488
Seung K Kim · Stanford University · R01 · FY2021 · DK

Genetic Basis of Host Infectivity by Cryptosporidium

$690,377
L David Sibley · Washington University · R01 · FY2024 · AI

Thyroid Physiology Studies of Inherited Disorders

$690,177
Samuel Refetoff · University Of Chicago · R01 · FY2018 · DK

Developing gene therapy strategies to treat alpha thalassemia

$690,110
Tippi Mackenzie · University Of California, San Francisco · R01 · FY2024 · HL

Functional genomics of evolutionary conserved long noncoding RNAs in Drosophila

$690,000
Carlos A Machado · University Of Maryland, College Park · · FY2017 · BIO

Development of CRISPR/Cas9-based exon-skipping strategies for the treatment of USH-associated deafness

$689,919
Xue Z Liu · University Of Miami School Of Medicine · R01 · FY2024 · DC

Investigating the mechanisms of driver genes associated with ancestry and aggressiveness in prostate cancer

$689,827
Joshua D Campbell · Boston University Medical Campus · R01 · FY2025 · CA

Combined Molecular Excision Therapy (CMET) for Eliminating HIV-1

$689,734
Howard Eliot Gendelman · University Of Nebraska Medical Center · R01 · FY2018 · MH

Structure-Function Analysis of Mxra8 Interaction with Alphaviruses.

$689,563
Michael S. Diamond · Washington University · R01 · FY2022 · AI

Gene regulatory networks controlling smooth muscle phenotype and vasculardisease risk

$689,474
Thomas None Quertermous · Stanford University · R01 · FY2025 · HL

Ocular Gene Therapy

$689,405
Zhijian Wu · National Eye Institute · ZIA · FY2017 · EY

Development of gene editing based therapy for cardiovascular diseases

$689,276
Yuqing E Chen · University Of Michigan At Ann Arbor · R01 · FY2024 · HL

Proteomic determinants of direct measures of insulin sensitivity

$689,217
Themistocles Leonard Assimes · Stanford University · R01 · FY2022 · DK

Mechanisms and therapeutic implications of human clonal hematopoiesis (CH) mutations

$689,125
Eirini Papapetrou · Icahn School Of Medicine At Mount Sinai · R01 · FY2022 · CA

Core A- Administration, Education, and Mentoring

$689,034
Michael R Garrett · University Of Mississippi Med Ctr · P20 · FY2025 · GM

Construction of the integrated human cortical organoids to investigate neurodevelopmental disorders

$688,826
In-Hyun Park · Yale University · R01 · FY2019 · MH