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17,054 grants matching genome editing

Structure and Activation of a Multiprotein Signaling Complex

$694,073
Roy A Mariuzza · Univ Of Maryland, College Park · R01 · FY2018 · AI

Roles for uniquely human enhancers in brain development and WNT signaling

$694,047
Debra Silver · Duke University · R01 · FY2024 · MH

Function-based exploration of genetic variation at genome-scale

$694,040
Lars M Steinmetz · Stanford University · R01 · FY2024 · HG

Function-based exploration of genetic variation at genome-scale

$694,040
Lars M Steinmetz · Stanford University · R01 · FY2025 · HG

Streamlined development of an IND with the silica nanocapsule loaded with Cas9 genome editors to disrupt the dominant BEST1 mutant allele

$693,945
Krishanu Saha · University Of Wisconsin-Madison · U19 · FY2024 · NS

Collaborative Research: Reversing evolution to understand the genetic basis of species divergence

$693,850
Carlos A Machado · University Of Maryland, College Park · · FY2018 · BIO

Large scale nutrigenetics and genomics in a tractable metazoan model

$693,788
Albertha Johanna Walhout · Univ Of Massachusetts Med Sch Worcester · R01 · FY2018 · DK

Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editing

$693,571
Bo Yang · University Of Michigan At Ann Arbor · R01 · FY2022 · HL

Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editing

$693,571
Bo Yang · University Of Michigan At Ann Arbor · R01 · FY2023 · HL

Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editing

$693,571
Bo Yang · University Of Michigan At Ann Arbor · R01 · FY2020 · HL

Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editing

$693,571
Bo Yang · University Of Michigan At Ann Arbor · R01 · FY2021 · HL

Elucidating prostate cancer risk mechanisms through large-scale cistrome wide association studies

$693,457
Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2022 · CA

Mapping, modeling, and manipulating 3D contacts in vascular cells to connect risk variants to disease genes

$693,228
Jesse M Engreitz · Stanford University · R01 · FY2023 · HL

Mapping, modeling, and manipulating 3D contacts in vascular cells to connect risk variants to disease genes

$693,192
Jesse M Engreitz · Stanford University · R01 · FY2025 · HL

Post-transcriptional Regulatory Networks

$692,945
Quaid Morris · Sloan-Kettering Inst Can Research · R01 · FY2023 · HG

Collaborative Research: Deep-sequencing analysis of edited metabolic pathways to uncover, model, and overcome the epistatic constraints upon optimization

$692,761
Christopher J Marx · Regents Of The University Of Idaho · · FY2017 · BIO

CRISPR-induced cardiovascular progenitor cells to repair myocardial infarction

$692,459
Yigang Wang · University Of Cincinnati · R01 · FY2021 · HL

Structure and Activation of a Multiprotein Signaling Complex

$692,071
Roy A Mariuzza · Univ Of Maryland, College Park · R01 · FY2020 · AI

Combination Adjuvants to Activate Human Dendritic Cell Subsets and B Cells

$692,040
Jacques F Banchereau · Jackson Laboratory · U01 · FY2016 · AI

Structure and Activation of a Multiprotein Signaling Complex

$691,950
Roy A Mariuzza · Univ Of Maryland, College Park · R01 · FY2021 · AI

Pro-Inflammatory Stem Cell Variants in Cystic Fibrosis

$691,846
Frank D. McKeon · University Of Houston · R01 · FY2022 · HL

ASB13 Control of EBV Life Cycle in B Cell and Epithelial Cell Cancers

$691,788
Renfeng Li · University Of Pittsburgh At Pittsburgh · R01 · FY2025 · AI

Development of platforms for sorting, production, editing of beta cells

$691,470
Amit Choudhary · Broad Institute, Inc. · R01 · FY2023 · DK

Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's Disease

$691,408
Jubao Duan · Endeavor Health Clinical Operations · R01 · FY2023 · AG

Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's Disease

$691,408
Jubao Duan · Endeavor Health Clinical Operations · R01 · FY2024 · AG