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17,054 grants matching genome editing

Proteomic determinants of direct measures of insulin sensitivity

$695,603
Themistocles Leonard Assimes · Stanford University · R01 · FY2020 · DK

Implementing A QSP Platform to Predict and Test Drugs for Metabolic Associated Fatty Liver Disease Genetic Variants in an iPSC-cell Based Human Biomimetic Liver Microphysiology System

$695,586
Mark T. Miedel · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · DK

Site-directed RNA editing: a new method to correct disease causing mutations

$695,524
Gail Mandel · Oregon Health & Science University · R01 · FY2013 · NS

Variant to Function Mapping of B-ALL Risk Loci

$695,464
Vijay Ganesh Sankaran · Boston Children'S Hospital · R01 · FY2024 · CA

Thyroid Hormone Signaling in Human Hepatocytes

$695,438
Anthony N Hollenberg · Weill Medical Coll Of Cornell Univ · R01 · FY2019 · DK

Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer

$695,331
Jesse Samuel Boehm · Massachusetts Institute Of Technology · R01 · FY2022 · CA

Molecular Biomarkers in pathogenesis of Lymphangioleiomyomatosis (LAM)

$695,144
Jeanine M D'armiento · Columbia University Health Sciences · R01 · FY2024 · HL

BCM-Rice resource for the analysis of somatic gene editing in mice

$695,141
Jason D Heaney · Baylor College Of Medicine · U42 · FY2020 · OD

Cell Therapies for Cooley's Anemia

$695,090
Thomas M Ryan · University Of Alabama At Birmingham · R56 · FY2014 · HL

Center for Iron and Heme Disorders (CIHD)

$694,965
John Dearborn Phillips · University Of Utah · U54 · FY2020 · DK

Mechanism-informed identification of causal enhancer variants

$694,900
Emma Kirsten Farley · University Of California, San Diego · R01 · FY2025 · HG

Chemogenomic Profiling of Plasmodium Falciparum Responses and Resistance

$694,778
John Adams · University Of South Florida · R01 · FY2022 · AI

Structural Variation and Hematological Traits

$694,774
Alexander P Reiner · University Of Washington · R01 · FY2025 · HL

Identifying Osteoporosis Genes by Whole Genome Sequencing and Functional Validation in Zebra Fish

$694,650
Yi-Hsiang Hsu · Hebrew Rehabilitation Center For Aged · R01 · FY2021 · AR

C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approaches

$694,575
Bruce R Conklin · J. David Gladstone Institutes · R01 · FY2025 · AG

Gene regulatory networks controlling smooth muscle phenotype and vasculardisease risk

$694,555
Thomas None Quertermous · Stanford University · R01 · FY2024 · HL

Proteomic determinants of direct measures of insulin sensitivity

$694,532
Themistocles Leonard Assimes · Stanford University · R01 · FY2021 · DK

iPSC-based blood regenerative therapies for AIDS

$694,457
Igor I Slukvin · University Of Wisconsin-Madison · R01 · FY2017 · HL

iPSC-based blood regenerative therapies for AIDS

$694,457
Igor I Slukvin · University Of Wisconsin-Madison · R01 · FY2016 · HL

Discovery of conserved molecular mechanisms underlying population-wide variation in toxin responses

$694,440
Erik Christian Andersen · Northwestern University · R01 · FY2021 · ES

Learning Regulatory Drivers of Chromatin and Expression Dynamics during Nuclear Reprogramming

$694,416
Anshul Kundaje · Stanford University · R01 · FY2017 · HG

Gene editing in the brain with CRISPR-PEG

$694,396
Hye Young Lee · University Of Texas Hlth Science Center · R01 · FY2021 · MH

In vivo delivery of CRISPR Cas9-guide RNA nucleoprotein complexes using the nanoPOD platform

$694,345
John Christian Tilton · Case Western Reserve University · UG3 · FY2021 · HL

In vivo delivery of CRISPR Cas9-guide RNA nucleoprotein complexes using the nanoPOD platform

$694,345
John Christian Tilton · Case Western Reserve University · UG3 · FY2020 · HL

Transancestral fine mapping and functional dissection of autophagy-related SLE risk loci

$694,180
Betty P. Tsao · Medical University Of South Carolina · R01 · FY2022 · AR