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38,696 grants matching als

Malaria Transmission Blocking Vaccine Discovery

$989,562
Patrick Duffy · National Institute Of Allergy And Infectious Diseases · ZIA · FY2021 · AI

Genetic Toxicity Testing Services for the NTP

$989,488
Les Recio · Integrated Laboratory Systems, Llc · N01 · FY2018 · ES

Liver Cancer Program

$989,424
Anuradha Budhu · Division Of Basic Sciences - Nci · ZIA · FY2023 · CA

Multivalent Adjuvant Immunization to Prevent Hospital Acquired Infections

$989,399
Brad J Spellberg · Exbaq Llc · R42 · FY2023 · AI

Biochemical Analysis of Multidrug Resistance-linked Transport Proteins

$988,986
Suresh Ambudkar · Division Of Basic Sciences - Nci · ZIA · FY2013 · CA

Resource for the Development of Biomedical Accelerator Mass Spectrometry (AMS)

$988,679
Kenneth W Turteltaub · University Of Calif-Lawrnc Lvrmr Nat Lab · P41 · FY2019 · GM

From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease

$988,674
Leslie Michels Thompson · University Of California-Irvine · P01 · FY2020 · NS

THERE IS A CRITICAL NEED TO QUICKLY DEVELOP A DIVERSE SET OF BETTER-ADAPTED AND HIGHER-YIELDING TRIPLOID M. XGIGANTEUS (MXG) CULTIVARS WITH OPTIMIZED COMPOSITION FOR THE BIOMASS INDUSTRIES IN THE NORTHERN AND SOUTHERN U.S. CURRENTLY, THERE IS ONLY ONE GENOTYPE OF MXG ('ILLINOIS') AVAILABLE IN THE U.S. FOR FARMERS TO GROW AS A BIOMASS CROP; THIS CULTIVAR IS INSUFFICIENTLY WINTER-HARDY IN ZONE 5 AND COLDER, AND FLOWERS TOO EARLY IN THE SOUTHERN U.S. TO ACHIEVE HIGH YIELDS. WE WILL LEVERAGE OUR EXTENSIVE GERMPLASM COLLECTION AND PRIOR PHENOTYPIC DATA FROM MULTI-LOCATION TESTING OF GERMPLASM PANELS TO BREED NEW TRIPLOID MXG GENOTYPES. INITIAL FIELD TESTING WILL BE CONDUCTED IN IL AND AL, STARTING WITH ~100 GENOTYPES ALREADY IN-HAND. ELITE SELECTIONS WILL BE TESTED IN FARMER TRIALS IN COLLABORATION WITH STAKEHOLDERS. TO ACCELERATE MISCANTHUS BREEDING, WE WILL BUILD UPON OUR PREVIOUS STUDIESBY DEVELOPING OPTIMIZED, VALIDATED GENOMIC SELECTION TOOLS TO ENABLE HIGHLY EFFICIENT SELECTION OF MISCANTHUS FOR YIELD, WINTER-HARDINESS (NORTHERN ADAPTATION), LATE FLOWERING (SOUTHERN ADAPTATION), AND STEM COMPOSITION (QUALITY). BY DEVELOPING A NEW SHORT COURSE AT AAMU AND THROUGH AN EXISTING HUDSONALPHA TRAINING PROGRAM, WE WILL EDUCATE AND INSPIRE THE NEXT GENERATION OF PLANT GENOMICISTS, WITH A FOCUS ON UNDERREPRESENTED MINORITY GROUPS AND WOMEN. THE LONG TERM IMPACT WILL BE AN EXPANDED, VIBRANT BIOMASS INDUSTRY, INCREASED OPPORTUNITY FOR RURAL AMERICA, AND A DIVERSE WORKFORCE WITH THE CROSS-DISCIPLINARY SKILLS NEEDED TO SOLVE THE IMPORTANT PROBLEMS FACING AGRICULTURE AND SOCIETY. THE PROJECT DIRECTLY ADDRESSES THE PROGRAM AREA BIOMASS FEEDSTOCK GENETIC DEVELOPMENT AND EVALUATION (A6152).

$988,335
University Of Illinois · · FY2018 · National Institute of Food and Agriculture

Biochemical Analysis of Multidrug Resistance-linked Transport Proteins

$987,871
Suresh Ambudkar · Division Of Basic Sciences - Nci · ZIA · FY2009 · CA

Raman Spectroscopic Studies of Amyloids

$987,826
Jennifer Lee · National Heart, Lung, And Blood Institute · ZIA · FY2025 · HL

Leveraging natural phenotypic variations of heterogenous ALS populations-in-a-dish to enable scalable drug discovery

$987,822
Justin Kawika Ichida · University Of Southern California · R01 · FY2023 · NS

Control Of Behavior By Drug Injections

$987,702
Steven Goldberg · National Institute On Drug Abuse · ZIA · FY2013 · DA

Structural Biology of HIV Assembly and Maturation

$987,649
Alasdair C. Steven · National Institute Of Arthritis And Musculoskeletal And Skin Diseases · ZIA · FY2017 · AR

Red Cell Biology

$987,510
David M. Bodine · National Human Genome Research Institute · ZIA · FY2019 · HG

Programming T Cell Fates for Therapeutic Use

$987,437
Luca Gattinoni · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA

Super resolution microscope for the imaging core facility

$987,190
Hiroshi Nishimune · University Of Kansas Medical Center · S10 · FY2019 · OD

From pathogenesis to new therapeutic targets in diffuse large B cell lymphoma

$987,000
Riccardo Dalla-Favera · Columbia University Health Sciences · R35 · FY2023 · CA

From pathogenesis to new therapeutic targets in diffuse large B cell lymphoma

$987,000
Riccardo Dalla-Favera · Columbia University Health Sciences · R35 · FY2025 · CA

Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion

$986,853
Leonard Petrucelli · Mayo Clinic Jacksonville · P01 · FY2017 · NS

Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion

$986,853
Leonard Petrucelli · Mayo Clinic Jacksonville · P01 · FY2018 · NS

Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

$986,763
Swee Lay Thein · National Heart, Lung, And Blood Institute · ZIA · FY2023 · HL

Molecular mechanisms of immune evasion in Staphylococcus aureus

$986,709
Michael Otto · National Institute Of Allergy And Infectious Diseases · ZIA · FY2017 · AI

Translation of a personalized, non-invasive smartphone app for hemoglobin monitoring for chronic anemia patients

$986,670
Erika Amy Tyburski · Sanguina, Llc · R44 · FY2024 · HL

ALS Efficiently Networking Advanced Beam Line Experiments (ALS-ENABLE)

$986,503
Paul David Adams · University Of Calif-Lawrenc Berkeley Lab · P30 · FY2025 · GM

Regulation and functional effects of localized RNAs

$986,498
Stavroula Mili · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA