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15,440 grants matching organoids

Alloreactive and autoreactive immune-mediated mechanisms of impaired epithelial regeneration in the GI tract

$638,529
Alan M Hanash · Sloan-Kettering Inst Can Research · R01 · FY2019 · HL

Impact of Mitochondrial Lipidomic Dynamics and its Interaction with APOE Isoforms on Brain Aging and Alzheimers Disease

$638,436
Ling Li · University Of Minnesota · R01 · FY2025 · AG

Beyond Gene Dosage: Understanding Down Syndrome via 4D Genome Organization

$638,318
Wenbo Li · University Of Texas Hlth Sci Ctr Houston · U01 · FY2020 · HL

Epigenomic Reprogramming in Patient Derived Models of Colorectal Cancer

$638,270
Xiling Shen · Duke University · U01 · FY2018 · CA

TMPRSS2 as a potential target for treatments of COVID-19 and respiratory infectious viruses in lung

$638,230
Ya-Wen Chen · Icahn School Of Medicine At Mount Sinai · R01 · FY2024 · HL

Investigating protective adaptive immune responses to influenza antigens using human tonsil organoids

$638,169
Lisa Wagar · University Of California-Irvine · R01 · FY2024 · AI

The role of tuft cells in norovirus pathogenesis

$638,139
Craig Brian Wilen · Yale University · R01 · FY2023 · AI

The role of tuft cells in norovirus pathogenesis

$638,139
Craig Brian Wilen · Yale University · R01 · FY2022 · AI

The role of tuft cells in norovirus pathogenesis

$638,139
Craig Brian Wilen · Yale University · R01 · FY2024 · AI

A Novel Transcription Factor-Driven Approach for Mural Progenitor Cells Generation

$638,118
Juan M Melero-Martin · Boston Children'S Hospital · R01 · FY2025 · HL

A Novel Transcription Factor-Driven Approach for Mural Progenitor Cells Generation

$638,118
Juan M Melero-Martin · Boston Children'S Hospital · R01 · FY2024 · HL

Developing a patient-specific organoid model of pulmonary fibrosis using iPSCs

$638,086
Darrell N. Kotton · Boston University Medical Campus · U01 · FY2024 · HL

Utilizing nucleic acid scavengers to elucidate how DNA/RNA-containing DAMPs promote pancreatic cancer metastasis and to mitigate such processes

$638,056
Bruce Alan Sullenger · Duke University · R01 · FY2025 · CA

Proteogenetics of Autism Spectrum Disorders

$637,920
John Robert Yates · Scripps Research Institute, The · R01 · FY2022 · MH

Transitional Alveolar Epithelial Cells in Normal Lung Development

$637,913
Parviz Minoo Minoo · University Of Southern California · R01 · FY2025 · HL

CRISPR/Cas9-based gene editing approaches for the treatment of USH2A-associated diseases

$637,558
Qin Liu · Massachusetts Eye And Ear Infirmary · R01 · FY2023 · EY

Intestinal uptake, translocation, biodistribution, and toxicity of ingested environmentally relevant micro-nanoplastics (MNPs) and the role of inflammation using advanced cellular and in vivo models

$637,553
Philip Demokritou · Rutgers Biomedical And Health Sciences · R01 · FY2024 · ES

Inhibition of the Wnt Receptor Complex by the Tumor Suppressor Adenomatous Polyposis Coli

$637,519
Yasmath Ahmed · Dartmouth College · R01 · FY2023 · CA

Inhibition of the Wnt Receptor Complex by the Tumor Suppressor Adenomatous Polyposis Coli

$637,519
Yasmath Ahmed · Dartmouth College · R01 · FY2022 · CA

Modeling Genetic Inner Ear Disorders with Human Pluripotent Stem Cells

$637,479
Eri Hashino · Indiana University Indianapolis · R01 · FY2021 · DC

HLA-E and NKG2A define a novel immune checkpoint axis in non-muscle-invasive bladder cancer

$637,395
Amir Horowitz · Icahn School Of Medicine At Mount Sinai · R01 · FY2024 · CA

Engineering high performing microfluidic system for rapid non-invasive isolation and expansion of circulating tumor-reactive lymphocytes

$637,371
Shana O Kelley · Northwestern University At Chicago · R01 · FY2025 · CA

Mechanisms of telomere-induced disease: Role of intestinal malabsorption, barrier dysfunction and dsybiosis.

$637,298
Ergun Sahin · Baylor College Of Medicine · R01 · FY2025 · DK

Targeting platinum(IV) prodrug to GBM tumors using a brevican-binding peptide

$637,130
Choi-Fong Cho · Brigham And Women'S Hospital · R01 · FY2024 · CA

Prioritization and Bioactivity Characterization of Novel Bile Acids Produced by the Microbiome

$637,000
Robert Andrew Quinn · Michigan State University · R01 · FY2024 · DK