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17,054 grants matching genome editing

Developing second generation SCID pig models: filling the gaps to improve translation of therapeutics in regenerative medicine

$730,384
Christopher Tuggle · Iowa State University · R24 · FY2023 · OD

Development of a versatile paired prime editing toolkit for CFTR gene correction

$730,268
Tingting Jiang · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · HL

Preclinical optimization of a gene therapy for erythromelalgia and chronic pain

$730,264
Fernando Aleman Guillen · Navega Therapeutics, Inc. · U44 · FY2022 · NS

Foundational Mapping of the Neural Circuits that Control Intrinsic Lung Function

$730,163
Xin Sun · University Of California, San Diego · OT2 · FY2020 · OD

Defining and perturbing gene regulatory dynamics in the developing human heart to understand mechanisms of congenital heart defects

$730,158
William James Greenleaf · Stanford University · R01 · FY2025 · HL

Establishing an Integrated Platform for Diploid Germplasm Conservation in Zebrafish (Danio rerio)

$730,053
Jose B Cibelli · Michigan State University · R24 · FY2024 · OD

Modulation of lung immunity by epithelial cells from older individuals

$729,960
Anna Karolina Palucka · Jackson Laboratory · U19 · FY2024 · AI

Fine-mapping psychiatricdisease variants that affect post-transcriptional gene regulation

$729,438
David Arthur Knowles · New York Genome Center · R56 · FY2022 · MH

NICHD Health Research Board Of Ireland Neural Tube Defects Study

$729,332
James L Mills · Eunice Kennedy Shriver National Institute Of Child Health & Human Development · Z01 · FY2008 · HD

Understanding Complex Gene Editing Systems and RNA Biology in Oxytricha

$729,213
Laura F Landweber · Columbia University Health Sciences · R35 · FY2017 · GM

Understanding Complex Gene Editing Systems and RNA Biology in Oxytricha

$729,213
Laura F Landweber · Columbia University Health Sciences · R35 · FY2018 · GM

Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies

$729,100
Suk See De Ravin · National Institute Of Allergy And Infectious Diseases · ZIA · FY2021 · AI

Human Mitochondrial Variation and Sudden Cardiac Arrest Risk and Resuscitation

$728,907
Dan E Arking · Johns Hopkins University · R01 · FY2024 · HL

Scalable platform for optimizing human cardiac tissue engineering via optical pacing and on-demand oxygenation

$728,876
Emilia Entcheva · George Washington University · R01 · FY2019 · HL

Late Effects Prediction using Clinical Phenotypes and Whole Genome Sequencing

$728,864
Yutaka Yasui · St. Jude Children'S Research Hospital · R01 · FY2019 · CA

Development of marmoset models of neurodegenerative disease using embryonic stem cell-based gene-editing approaches

$728,786
Kuo-Fen Lee · Salk Institute For Biological Studies · R24 · FY2019 · OD

Multiplex base/prime editors for in vivo selection of modified HSPCs in hemoglobinopathy

$728,713
Hans-Peter Kiem · Fred Hutchinson Cancer Center · R01 · FY2024 · HL

Development of a hamster model for hepatitis B virus infection

$728,653
Zhongde Wang · Utah State University · R01 · FY2025 · AI

Development of a porcine model of polycystic kidney disease by multiplex gene-editing.

$728,169
Daniel Fred Carlson · Recombinetics, Inc. · R44 · FY2018 · DK

Role of ARMS2 mutations in age-related macular degeneration

$728,017
Patsy M Nishina · Jackson Laboratory · R01 · FY2025 · EY

Adenine metabolism in cardiac repair

$727,945
Arjun Deb · University Of California Los Angeles · R01 · FY2025 · HL

Engineering Novel Precision Genome Editing Tools

$727,790
Audrone Lapinaite · Arizona State University-Tempe Campus · DP2 · FY2022 · GM

Understanding Complex Gene Editing Systems and RNA Biology in Oxytricha

$727,524
Laura F Landweber · Columbia University Health Sciences · R35 · FY2019 · GM

Development of CRISPR/Cas9-based exon-skipping strategies for the treatment of USH-associated deafness

$727,454
Xue Z Liu · University Of Miami School Of Medicine · R01 · FY2022 · DC

Designer Molecular Probes for Biomedical Applications

$727,444
Ivan Julian Dmochowski · University Of Pennsylvania · R35 · FY2019 · GM