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17,828 grants matching crispr

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD

$733,242
Manolis Kellis · Massachusetts Institute Of Technology · R01 · FY2023 · AG

Variant to gene mapping for Alzheimer's Disease

$733,237
Struan F A Grant · Children'S Hosp Of Philadelphia · R01 · FY2019 · AG

Mechanisms of Toxicity Induced by EWS/FLI1 Overdose in Ewing Sarcoma

$733,093
Kimberly Stegmaier · Dana-Farber Cancer Inst · R01 · FY2023 · CA

A nanoparticle delivery system for CRISPR/Cas9 based therapeutics

$732,982
Kenichi Kuroda · Atgc, Inc. · R42 · FY2019 · TR

MAGIC tools for genome-wide mosaic analysis with existing Drosophila resources

$732,439
Chun Han · Cornell University · R24 · FY2022 · OD

Self-eliminating strategy to control gene drive

$732,437
Zach N Adelman · Texas A&M Agrilife Research · R01 · FY2020 · AI

Determinants of AAV Tropism

$732,144
Aravind Asokan · Duke University · R01 · FY2024 · HL

Mechanisms of Oxygen Toxicity

$731,827
Isha Himani Jain · J. David Gladstone Institutes · R01 · FY2025 · HL

Elucidating the Signaling Landscapes Underlying Cellular and Regional Specification During Human Brain Development

$731,648
Fikri Birey · Emory University · R01 · FY2024 · MH

Advanced development of the Cancer Dependency Map portal (DepMap.org)

$731,592
Philip Montgomery · Broad Institute, Inc. · U24 · FY2023 · CA

Modeling Pathways of Early Growth Dysregulation at the GEJ

$731,451
Stephen J Meltzer · Johns Hopkins University · R01 · FY2024 · DK

Unraveling the Genetic Programs Engaged in ASD Neurons Through Coupled Transcriptomic and Phenotypic Readouts

$731,446
Samouil Farhi · Broad Institute, Inc. · R01 · FY2023 · MH

Project 2-Identifying and exploiting metabolic vulnerabilities in PDAC

$731,128
Ronald Anthony Depinho · University Of Tx Md Anderson Can Ctr · P01 · FY2021 · CA

Identification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and Pathogenesis

$731,052
Gaya K. Amarasinghe · Washington University · R01 · FY2025 · AI

In Vivo RNA-Mediated Gene Editing of Hemophilia A

$730,924
Drew Weissman · University Of Pennsylvania · R01 · FY2018 · HL

Discovery, Biology and Risk of Inherited Variants in Glioma

$730,884
Melissa L Bondy · Stanford University · R01 · FY2024 · CA

Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic risk

$730,623
Ginger E Nicol · Washington University · R01 · FY2022 · MH

Chemical genetics of M. tuberculosis DosRST signaling and persistence

$730,444
Robert B Abramovitch · Michigan State University · R01 · FY2022 · AI

In Vivo Gene Editing of B cells with NICE-AAV Vectors

$730,441
Christopher W Peterson · Fred Hutchinson Cancer Center · R01 · FY2025 · AI

Inflammatory Signaling in the Leptomeninges

$730,398
Adrienne A. Boire · Sloan-Kettering Inst Can Research · R01 · FY2025 · CA

Targeting the gut-liver axis in cardiovascular disease

$730,352
Thomas A Vallim · University Of California Los Angeles · R01 · FY2024 · HL

Integrating systems immunology with immunometabolism and cancer immunity

$730,271
Hongbo Chi · St. Jude Children'S Research Hospital · R35 · FY2021 · CA

Preclinical optimization of a gene therapy for erythromelalgia and chronic pain

$730,264
Fernando Aleman Guillen · Navega Therapeutics, Inc. · U44 · FY2022 · NS

Defining and perturbing gene regulatory dynamics in the developing human heart to understand mechanisms of congenital heart defects

$730,158
William James Greenleaf · Stanford University · R01 · FY2025 · HL

Molecular mechanisms of selective vulnerability of neurons to tauopathy

$729,556
Martin Kampmann · University Of California, San Francisco · R01 · FY2025 · AG