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17,054 grants matching genome editing

The intersection of RNA biology and tumor biology

$748,148
Joshua T Mendell · Ut Southwestern Medical Center · R35 · FY2019 · CA

Enhancing The Value of Pigs for Agriculture and Biomedical Applications By Using Novel Genome Editing Strategies

$748,114
Kiho Lee · University Of Missouri-Columbia · R01 · FY2025 · OD

Physiological and therapeutic effects of ANGPTL3 variants in mice and humans

$748,107
Marina Cuchel · University Of Pennsylvania · R01 · FY2022 · HL

Bimodal gene editing strategy for HIV/AIDS cure in non-human primates

$747,950
Tricia Helen Burdo · Temple Univ Of The Commonwealth · R56 · FY2019 · AI

Cardiac Lineage-Specific Molecular Mechanisms of Heart Failure

$747,916
Neil C Chi · University Of California, San Diego · R01 · FY2024 · HL

Vascularized kidney organoids on chip for efficacy and toxicity testing of somatic genome editing

$747,860
Ryuji Morizane · Massachusetts General Hospital · U01 · FY2019 · EB

Genetic modifiers of congenital heart disease in 22q11.2 deletion syndrome

$747,800
Bernice E. Morrow · Albert Einstein College Of Medicine · R01 · FY2024 · HL

A Novel Role for NFATC1 in Modulating Cardiac Excitability

$747,656
Martin Tristani-Firouzi · University Of Utah · R01 · FY2021 · HL

Rewiring of regulatory networks in breast cancer by transcription factor isoforms

$747,298
Marc Vidal · Dana-Farber Cancer Inst · U01 · FY2018 · CA

Development and Application of Computational Methods for Single Cell DNA Sequencing Data

$747,149
Peter Park · Harvard Medical School · R01 · FY2022 · HG

Multiplex base/prime editors for in vivo selection of modified HSPCs in hemoglobinopathy

$747,027
Hans-Peter Kiem · Fred Hutchinson Cancer Research Center · R01 · FY2021 · HL

A fluorescent reporter detecting precise homologous recombination transgenesis activity

$747,005
Trisha Brock · Kdt, Inc · R44 · FY2017 · HD

Northwestern University Skin Biology and Diseases Resource-based Center

$746,969
Amy S Paller · Northwestern University At Chicago · P30 · FY2022 · AR

Novel therapeutics for FSHD

$746,947
Charles P Emerson · Univ Of Massachusetts Med Sch Worcester · P50 · FY2023 · HD

Joint genomic and statistical analyses of schizophrenia and bipolar to decipher genetic susceptibility

$746,636
Roel A Ophoff · University Of California Los Angeles · R01 · FY2020 · MH

University of Michigan Skin Biology and Diseases Resource-based Center

$746,418
Johann Eli Gudjonsson · University Of Michigan At Ann Arbor · P30 · FY2022 · AR

CAREER: Investigating Chromatin Dynamics Underlying Activity-Induced Neuronal Transcription Using CRISPR Technologies

$746,288
Lei S Qi · Stanford University · · FY2021 · BIO

Evolving High Potency AAV Vectors for Neuromuscular Genome Editing

$746,139
Aravind Asokan · Duke University · UG3 · FY2018 · AR

CD4 T cell-targeted nanoparticle in vivo delivery of CRISPR/Cas9 genome editors for HIV cure

$745,808
Wenhui Hu · Temple Univ Of The Commonwealth · R01 · FY2022 · AI

Pathogenic hotspots illuminate mechanism and therapeutic potential in arrhythmogenic cardiomyopathy

$745,470
Victoria Parikh · Stanford University · R01 · FY2024 · HL

T cell-targeted lentiviral vectors with Cas9/RNP for the in vivo gene therapy of HIV-AIDS

$745,410
Priti Kumar · Yale University · R01 · FY2024 · AI

CCR5-mutant monkey model to facilitate the development of novel stem cell-based therapies for AIDS

$745,261
Igor I Slukvin · University Of Wisconsin-Madison · R24 · FY2018 · OD

PTPN22 R619W in NOD mice

$745,163
Linda A Sherman · Scripps Research Institute, The · U01 · FY2019 · AI

PTPN22 R619W in NOD mice

$745,163
Linda A Sherman · Scripps Research Institute, The · U01 · FY2021 · AI

PTPN22 R619W in NOD mice

$745,163
Linda A Sherman · Scripps Research Institute, The · U01 · FY2020 · AI