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15,895 grants matching artificial intelligence

Collaborative Research: EPIIC: Developing Emerging Technology Ecosystem Partnerships for Primarily Undergraduate Institutions

$799,996
Roberto A Flores · Christopher Newport University · · FY2023 · TIP

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS-TYPE 2 (PRRSV-2) IS A RAPIDLY EVOLVING RNA VIRUS IMPACTING ~30-50% OF BREEDING FARMS. SWINE PRODUCERS SEQUENCE THOUSANDS OF VIRUSES ANNUALLY AS PART OF DISEASE MANAGEMENT, BUT ARE FRUSTRATED BY LIMITATIONS IN TRANSLATING GENETIC DATA TO PHENOTYPIC INSIGHTS RELEVANT FOR DECISION-MAKING. OUR OBJECTIVE IS TO CREATE AN INTEGRATIVE DATA SCIENCE PLATFORM TO PREDICT THE IMMUNOGENIC AND EPIDEMIOLOGIC PHENOTYPE OF PRRSV-2 VARIANTS THROUGH BREAKING BARRIERS AND BUILDING CONNECTIVITY AMONG AI/ML ACROSS STRUCTURAL BIOLOGY, COMPUTATIONAL IMMUNOLOGY, AND GENOMIC EPIDEMIOLOGY.SPECIFICALLY, WE WILL APPLY UNSUPERVISED LEARNING TO IDENTIFY CLUSTERS (VARIANTS) OF CLOSELY RELATED GENETIC SEQUENCES WITHIN LARGE-SCALE DATABASES. WE WILL MEASURE STRUCTURAL DIVERGENCE BETWEEN VARIANTS (HYPOTHESIZED TO INFLUENCE IMMUNOGENICITY AND ANTIBODY BINDING) USING ALPHAFOLD 2.0, AN ARTIFICIAL INTELLIGENCE TOOL RECENTLY DEVELOPED FOR 3D STRUCTURAL PREDICTIONS OF PROTEIN FOLDING. WE WILL THEN APPLY MACHINE LEARNING TO EXPERIMENTAL DATA ON ANTIBODY CROSS-REACTIVITY AMONGST VARIANTS TO BUILD A MODEL THAT PREDICTS ANTIGENIC DISTANCE BASED ON GENETIC DISSIMILARITIES AND STRUCTURAL DIVERGENCE METRICS. LASTLY, WE WILL DEVELOP A MACHINE LEARNING ALGORITHM THAT PREDICTS A VARIANT'S EPIDEMIOLOGIC FITNESS (I.E., EXPANSION OF A GIVEN VARIANT THROUGH TIME) BASED ON ANTIGENIC DISTANCE, STRUCTURAL DIVERGENCE, AND PHYLOGENETIC FEATURES.WE WILL ALSO CREATE AN HTML-BASED VISUALIZATION PLATFORM THAT ALLOWS STAKEHOLDERS TO CLASSIFY AND CONTEXTUALIZE THEIR OWN SEQUENCES WITHIN THE BROADER PHENOTYPIC DIVERSITY OF THE VIRUS. THIS INTEGRATION OF BACK-END ANALYTICAL METHODS AND FRONT-END VISUALIZATION TOOLS WILL IMPROVE HUMAN-DATA INTERACTIONS SURROUNDING INTERPRETATION OF SEQUENCE DATA AND SUPPORT DECISION-MAKING ABOUT APPROPRIATE DISEASE MANAGEMENT AND IMMUNIZATION PRACTICES WITHIN THE SWINE INDUSTRY.

$799,993
Regents Of The University Of Minnesota · · FY2023 · National Institute of Food and Agriculture

Collaborative Research: RI: Medium: MoDL: Occams Razor in Deep and Physical Learning

$799,942
Pratik A Chaudhari · University Of Pennsylvania · · FY2022 · CSE

Collaborative Research: RI: Medium: A Rigorous, General Framework for Tractable Learning of Large-Scale DAGs from Data

$799,933
Pradeep K Ravikumar · Carnegie Mellon University · · FY2020 · CSE

SLES: Whitebox Testing, Debugging, and Repairing for Multi-module Autonomous Vehicles in Near-Collision Traffic Scenarios

$799,921
Tianyi Zhang · Purdue University · · FY2024 · CSE

Collaborative Research: RI: Medium: Superhuman Imitation Learning from Heterogeneous Demonstrations

$799,368
Brian Ziebart · University Of Illinois At Chicago · · FY2023 · CSE

Collaborative Research: Frameworks: MPI4AI: Enhancing Performance and Productivity of AI Science through Next-generation High Performance Communication Abstractions

$799,321
Bogdan F Nicolae · Illinois Institute Of Technology · · FY2025 · CSE

Collaborative Research: CPS Medium: Learning through the Air: Cross-Layer UAV Orchestration for Online Federated Optimization

$799,204
Abolfazl Hashemi · Purdue University · · FY2023 · CSE

Cardiovascular risk from comprehensive evaluation of the CT calcium score exam

$799,168
David L Wilson · Case Western Reserve University · R01 · FY2023 · HL

CCRI: ENS: Collaborative Research: Developing the Dialog Ecosystem to Support and Enhance Research in Spoken Dialog Systems

$798,909
David R Traum · University Of Southern California · · FY2019 · CSE

Risk Stratification for and Early Detection of Liver Cancer

$798,777
Fasiha Kanwal · Baylor College Of Medicine · U01 · FY2025 · CA

CAREER: Toward energy-efficient bio-inspired magnonic processing with nanomagnetic arrays

$798,759
Matthias B Jungfleisch · University Of Delaware · · FY2024 · MPS

Quantitative Biophotonics for Tissue Characterization and Function

$798,641
Amir H Gandjbakhche · Eunice Kennedy Shriver National Institute Of Child Health & Human Development · ZIA · FY2020 · HD

Artificial intelligence analysis of atrial remodeling evolution in patients with atrial fibrillation: Towards optimal ablation strategies

$798,602
Natalia A. Trayanova · Johns Hopkins University · R01 · FY2023 · HL

MRI: Development of Monitors for Alaskan and Canadian Auroral Weather in Space (MACAWS)

$798,259
Anthea J Coster · Northeast Radio Observatory Corp · · FY2017 · GEO

Human/AI Co-Orchestration of Dynamically-Differentiated Collaborative Classrooms

$797,995
Vincent Aleven · Carnegie Mellon University · · FY2018 · CSE

Quantitative model-based ESUS reclassification using cardiac and cerebral vessel wall MRI

$797,438
Mahmud Mossa-Basha · University Of Washington · R01 · FY2022 · NS

Exploring Social Learning in Collaborative Augmented Reality with Virtual Agents as Learning Companions

$797,242
Marjorie A Zielke · University Of Texas At Dallas · · FY2019 · CSE

Collaborative Research: Middle School Teacher and Student's Experiences with Artificial Intelligence via Computational Cameras

$797,174
Suren Jayasuriya · Arizona State University · · FY2020 · EDU

A Family Genetic Study of Autism and Fragile X Syndrome

$797,161
Molly C Losh · Northwestern University · R01 · FY2025 · MH

Explainable Machine Learning to Guide Prefrontal Brain Stimulation

$796,927
Zaid Harchaoui · University Of Washington · R01 · FY2024 · MH

UKRI/BBSRC-NSF/BIO: Interpretable and Noise-Robust Machine Learning for Neurophysiology

$796,800
Mohsen Imani · University Of California-Irvine · · FY2023 · BIO

Clinical evaluation of a commercially viable machine learning algorithm to automatically detect shoulder muscle pathology

$796,748
Lara Isabella Riem · Springbok, Inc. · R44 · FY2024 · AR

SBIR Phase II: Commercial Development of An Intelligent Modular Robot Platform for Research and Education

$796,678
Graham G Ryland · Barobo, Inc. · · FY2012 · TIP

Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics Discovery

$796,538
Feixiong Cheng · Cleveland Clinic Lerner Com-Cwru · U01 · FY2024 · AG