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15,440 grants matching organoids

Streamlined development of an IND with the silica nanocapsule loaded with Cas9 genome editors to disrupt the dominant BEST1 mutant allele

$693,945
Krishanu Saha · University Of Wisconsin-Madison · U19 · FY2024 · NS

Novel repeat associated non-AUG (RAN) proteins in sALS sFTD and SBMA: shared pathological features and unifying therapeutic opportunities

$693,663
Laura Pw Ranum · University Of Florida · R01 · FY2025 · NS

Gut bacterial metallophores in the development and severity of inflammatory bowel disease

$693,330
Derrick R Samuelson · University Of Nebraska Medical Center · R01 · FY2022 · DK

Analysis of protein interactions in neurodegenerative disease

$693,264
John Robert Yates · Scripps Research Institute, The · R01 · FY2022 · AG

Engineered probiotic for the treatment of autoimmune diseases

$692,859
Christine Beeton · Baylor College Of Medicine · R01 · FY2025 · AI

Nutrigenomics of Intestinal Vitamin D Action

$692,807
Sylvia S Christakos · Rutgers Biomedical And Health Sciences · R01 · FY2024 · DK

Analysis of protein interactions in neurodegenerative disease

$692,796
John Robert Yates · Scripps Research Institute, The · R01 · FY2025 · AG

Cancer Immune-Interception for Lynch Syndrome

$692,579
Eduardo Vilar Sanchez · University Of Tx Md Anderson Can Ctr · R01 · FY2021 · CA

Investigating human cis-regulatory evolution with hybrid iPS cells

$692,436
Hunter B Fraser · Stanford University · R01 · FY2023 · HG

Improving radiolabeled imaging and targeting of HER2 positive EG cancers using lovastatin

$692,343
Jason S Lewis · Sloan-Kettering Inst Can Research · R01 · FY2022 · CA

Leadership, Planning, and Evaluation

$692,337
Stanton L Gerson · Case Western Reserve University · P30 · FY2021 · CA

Interrogating the Role of Bacterial Methyl-modifying Enzymes in Pathoadaptation and Host Epigenetic Interference in Cancer

$692,241
Christopher D Johnston · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Understanding robust cellular information processing in complex environments and development of enabling single-cell analysis technologies

$692,014
Savas Tay · University Of Chicago · R35 · FY2025 · GM

Understanding robust cellular information processing in complex environments and development of enabling single-cell analysis technologies

$692,014
Savas Tay · University Of Chicago · R35 · FY2024 · GM

Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's Disease

$691,408
Jubao Duan · Endeavor Health Clinical Operations · R01 · FY2024 · AG

Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's Disease

$691,408
Jubao Duan · Endeavor Health Clinical Operations · R01 · FY2023 · AG

Prdm3/16 Regulate Chromatin Accessibility to Determine Alveolar Maturation

$690,923
Jeffrey A Whitsett · Cincinnati Childrens Hosp Med Ctr · R01 · FY2024 · HL

Mechanisms of resistance to Androgen Receptor inhibition in prostate cancer

$690,899
David Vanderweele · Division Of Basic Sciences - Nci · ZIA · FY2016 · CA

In vivo delivery of CRISPR Cas9-guide RNA nucleoprotein complexes using the nanoPOD platform

$690,751
John Christian Tilton · Case Western Reserve University · UG3 · FY2019 · HL

Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy

$690,558
Joseph C Wu · Stanford University · R01 · FY2023 · HL

Intracellular Collagen Sensing in Pulmonary Fibrosis

$690,557
Michael Podolsky · Weill Medical Coll Of Cornell Univ · R01 · FY2025 · HL

POLQ Synthetic Lethality in HR-Deficient Pancreatic Adenocarcinoma

$690,258
Diane M Simeone · New York University School Of Medicine · R01 · FY2021 · CA

Thyroid Physiology Studies of Inherited Disorders

$690,177
Samuel Refetoff · University Of Chicago · R01 · FY2018 · DK

Dietary fiber and soy protein-based microbiome metabolites for IBD prevention

$689,979
Eric C Martens · University Of Michigan At Ann Arbor · R01 · FY2023 · DK

Mitochondria in eosinophilic esophagitis pathogenesis

$689,971
Kelly A Whelan · Temple Univ Of The Commonwealth · R01 · FY2025 · DK