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Egil Lien

Univ Of Massachusetts Med Sch Worcester

$14,174,464
Attributed
$15,009,949
Total exposure
10
Grants
10
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.5M · FY200525
$2.5M$1.9M$1.3M$625K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$15,009,949 · 10

By mechanism

R01$9,135,376 · 4
U19$3,608,591 · 1
R21$1,836,219 · 4
R56$429,763 · 1

Top collaborators

Most similar at Univ Of Massachusetts Med Sch Worcester

Same institution · by research overlap

Others in their field

Top investigators on “Pathway Interactions

Research focus

Pathway InteractionsCytokineInfectionIn VivoResponsePathogenMediatingImmune ResponsePlagueBacteriaProteinsToll-Like ReceptorsSignal PathwayBiological ModelsInflammatorySignal TransductionYersinia PestisIn VitroMacrophageNatural ImmunityBacterial InfectionsTlr4 GeneCellsCell Death

Grant awards (32)

RNA splicing factor Raver1 controls cell death, inflammation, and innateimmunity$835,485
R01 · FY2025 · AI · contact PI
Regulation of Ninj1 oligomerization and cell membrane ruptures during cell death$203,094
R21 · FY2025 · AI · contact PI
RNA splicing factor Raver1 controls cell death, inflammation, and innateimmunity$835,485
R01 · FY2024 · AI · contact PI
Regulation of Ninj1 oligomerization and cell membrane ruptures during cell death$251,250
R21 · FY2024 · AI · contact PI
Caspase-8 as a focal hub in effector-triggered immunity$584,061
R01 · FY2023 · AI · contact PI
Caspase-8 as a focal hub in effector-triggered immunity$584,061
R01 · FY2022 · AI · contact PI
Bacterial activation and evasion of a PP2A phosphatase – Pyrin - Gasdermin D axis$209,375
R21 · FY2022 · AI · contact PI
Caspase-8 as a focal hub in effector-triggered immunity$584,061
R01 · FY2021 · AI · contact PI
Bacterial activation and evasion of a PP2A phosphatase – Pyrin - Gasdermin D axis$251,250
R21 · FY2021 · AI · contact PI
Caspase-8 as a focal hub in effector-triggered immunity$584,061
R01 · FY2020 · AI · contact PI
Caspase-8 as a focal hub in effector-triggered immunity$584,061
R01 · FY2019 · AI · contact PI
Bacterial inhibition of Pyrin inflammasome activation$209,375
R21 · FY2018 · AI · contact PI
Bacterial inhibition of Pyrin inflammasome activation$251,250
R21 · FY2017 · AI · contact PI
Adjuvants and Glucan Particle Vaccines$209,375
R21 · FY2017 · AI · contact PI
Adjuvants and Glucan Particle Vaccines$251,250
R21 · FY2016 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$395,387
R01 · FY2013 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$420,625
R01 · FY2012 · AI · contact PI
Improving the safety profile of DNA prime - protein boost HIV vaccinations$22,629
U19 · FY2012 · AI · contact PI
Improving the safety profile of DNA prime - protein boost HIV vaccinations$2,042,130
U19 · FY2011 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$421,505
R01 · FY2011 · AI · contact PI
Improving the safety profile of DNA prime - protein boost HIV vaccinations$875,648
U19 · FY2010 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$425,189
R01 · FY2010 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$415,101
R01 · FY2010 · AI · contact PI
Improving the safety profile of DNA prime - protein boost HIV vaccinations$668,184
U19 · FY2009 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$413,839
R01 · FY2009 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$235,601
R01 · FY2009 · AI · contact PI
The role of LPS-TLR4 signaling in live vaccine-induced protective responses$429,763
R56 · FY2008 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$342,850
R01 · FY2008 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$353,406
R01 · FY2007 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$364,538
R01 · FY2006 · AI · contact PI
The Role of LPS and Toll-like Receptors in Plague$373,900
R01 · FY2005 · AI
The Role of LPS and Toll-like Receptors in Plague$382,160
R01 · FY2004 · AI