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Focco Van Den Akker
Case Western Reserve University
$5,732,564
Attributed
$5,732,564
Total exposure
14
Grants
12
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).
Funding over time
peak $573.8K · FY2005–24$1M$750K$500K$250K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
Funding mix
By agency
NIH$5,732,564 · 14
By mechanism
R01$3,797,890 · 2
R21$1,642,355 · 4
R56$270,375 · 1
P41$21,944 · 7
Top collaborators
No co-investigators on record.
Most similar at Case Western Reserve University
Same institution · by research overlap
- Paul R Carey$6,813,776
- Hulya Bukulmez$622,740
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructureDesignAntibioticsCrystallographyComplexLeadBinding (Molecular Function)Inhibitor/AntagonistMolecularBeta-LactamaseInsightCarbapenemsResistanceSignal TransductionProteinsLinkAntibiotic ResistanceResortStructural BiologyBacterial InfectionsResearch PersonnelShapesNovel TherapeuticsMembrane
Grant awards (28)
Developing novel pyrazolidinone antibiotics targeting PBP3 to overcome resistance mechanisms$201,250
R21 · FY2024 · AI · contact PI
Developing novel pyrazolidinone antibiotics targeting PBP3 to overcome resistance mechanisms$241,500
R21 · FY2023 · AI · contact PI
Targeting Escherichia coli PBP1b using fragment-based approaches$241,500
R21 · FY2022 · AI · contact PI
Small molecule inhibitors of lytic transglycosylase to potentiate beta-lactam antibiotics$210,105
R21 · FY2021 · AI · contact PI
Targeting Escherichia coli PBP1b using fragment-based approaches$201,250
R21 · FY2021 · AI · contact PI
Small molecule inhibitors of lytic transglycosylase to potentiate beta-lactam antibiotics$240,750
R21 · FY2020 · AI · contact PI
Soluble guanylyl cyclase: mechanisms of activation and modulation$384,650
R01 · FY2014 · HL · contact PI
Soluble guanylyl cyclase: mechanisms of activation and modulation$373,660
R01 · FY2013 · HL · contact PI
Soluble guanylyl cyclase: mechanisms of activation and modulation$392,500
R01 · FY2012 · HL · contact PI
Soluble guanylyl cyclase: mechanisms of activation and modulation$392,500
R01 · FY2011 · HL · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE PROTEINS AND SIGNAL TRANSDUCTI$1,368
P41 · FY2011 · RR · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE PROTEINS AND SIGNAL TRANSDUCTI$559
P41 · FY2011 · RR · contact PI
Mechanistic studies and inhibition strategies for antibiotic resistance$262,585
R01 · FY2010 · AI · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE PROTEINS AND SIGNAL TRANSDUCTI$3,735
P41 · FY2010 · RR · contact PI
Mechanistic studies and inhibition strategies for antibiotic resistance$265,238
R01 · FY2009 · AI · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE PROTEINS AND SIGNAL TRANSDUCTI$2,067
P41 · FY2009 · RR · contact PI
Mechanism of activation of natriuretic peptide receptors$292,988
R01 · FY2008 · HL · contact PI
Mechanistic studies and inhibition strategies for antibiotic resistance$265,238
R01 · FY2008 · AI · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE AND SIGNAL TRANSDUCTION$4,882
P41 · FY2008 · RR · contact PI
Mechanism of activation of natriuretic peptide receptors$292,988
R01 · FY2007 · HL · contact PI
Mechanistic studies and inhibition strategies for antibiotic resistance$270,375
R01 · FY2007 · AI · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE AND SIGNAL TRANSDUCTION$3,852
P41 · FY2007 · RR · contact PI
Mechanism of activation of natriuretic peptide receptors$301,739
R01 · FY2006 · HL · contact PI
CRYSTALLOGRAPHIC STUDIES OF ANTIBIOTIC RESISTANCE AND SIGNAL TRANSDUCTION$5,481
P41 · FY2006 · RR · contact PI
Mechanism of activation of natriuretic peptide receptors$303,429
R01 · FY2005 · HL
Molecular mechanisms of antibiotic resistance$270,375
R56 · FY2005 · AI
Atrial natriuretic peptide receptor crystallization$153,000
R21 · FY2004 · DK
Atrial natriuretic peptide receptor crystallization$153,000
R21 · FY2003 · DK