← Leaderboards
Bryan L Roth
Univ Of North Carolina Chapel Hill
$59,246,636
Attributed
$80,287,574
Total exposure
27
Grants
18
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $10.2M · FY2005–25$20M$15M$10M$5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$102,557,362 · 29
By mechanism
N01$23,587,819 · 4
R01$21,254,143 · 7
U19$18,902,873 · 6
U24$14,263,452 · 1
P01$14,127,634 · 5
R37$5,158,053 · 1
Top collaborators
- Brian K. Shoichet24 shared
- Vadim Cherezov16 shared
- Marc G. Caron15 shared
- Raymond C Stevens15 shared
- Vsevolod Katritch5 shared
- Jian Jin4 shared
- Thomas L Kash4 shared
- Iris Lindberg4 shared
Most similar at Univ Of North Carolina Chapel Hill
Same institution · by research overlap
- John B Ludlow$375,179
- Gregory Joseph Basura$1,571,035
- Scott Stroup$4,198,462
Others in their field
Top investigators on “Receptor”
- Barton F Haynes · Duke University$182,835,224
- James C. Paulson · Scripps Research Institute$84,068,192
- Asrar B. Malik · University Of Illinois At Chicago$55,280,031
- Anthony O Caggiano · Cognition Therapeutics, Inc.$49,563,751
- Robert J Coffey · Vanderbilt University$48,115,270
- Robert H Vonderheide · University Of Pennsylvania$48,030,034
Research focus
ReceptorPharmaceutical PreparationsLigandsSignal TransductionProgramsAgonistStructureBaseG-Protein-Coupled ReceptorsIn VitroDrug DiscoveryComplexIn VivoSerotonin ReceptorArrestinsMolecularDesignLeadTechnologyNovel TherapeuticsPharmacologyProteinsBiochemicalSchizophrenia
Grant awards (154)
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$650,756
R37 · FY2025 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$599,826
R01 · FY2025 · MH · contact PI
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$563,447
R01 · FY2025 · DA · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$650,756
R37 · FY2024 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$605,561
R01 · FY2024 · MH · contact PI
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$563,447
R01 · FY2024 · DA · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$664,506
R37 · FY2023 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$611,184
R01 · FY2023 · MH · contact PI
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$566,946
R01 · FY2023 · DA · contact PI
Illuminating the Druggable GPCR-ome$2,239,055
U24 · FY2022 · DK · contact PI
Illuminating the Druggable GPCR-ome$749,510
U24 · FY2022 · DK · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$639,458
R37 · FY2022 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$629,016
R01 · FY2022 · MH · contact PI
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$582,640
R01 · FY2022 · DA · contact PI
Illuminating the Druggable GPCR-ome$2,241,036
U24 · FY2021 · DK · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$635,456
R37 · FY2021 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2021 · MH · contact PI
Illuminating the Druggable GPCR-ome$2,242,958
U24 · FY2020 · DK · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$635,456
R37 · FY2020 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2020 · MH · contact PI
Illuminating the Druggable GPCR-ome$2,243,887
U24 · FY2019 · DK · contact PI
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$634,832
R37 · FY2019 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2019 · MH · contact PI
Illuminating the Druggable GPCR-ome$2,245,696
U24 · FY2018 · DK · contact PI
Structure-Function of Opioid Receptors$1,391,835
P01 · FY2018 · DA
Structural Studies of Opioid Receptors, p 55$792,420
P01 · FY2018 · DA
Mechanistic insights into LSD actions at 5-HT2A serotonin receptors$646,833
R37 · FY2018 · DA · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2018 · MH · contact PI
Opioid Receptor Protein Production Core$327,065
P01 · FY2018 · DA
Structure-Based Discovery Opioid Receptor Ligands and Molecules, p. 83$148,996
P01 · FY2018 · DA
Management and Administration Core, p. 192$123,354
P01 · FY2018 · DA
NIMH Psychoactive Drug Screening Program$2,838,329
N01 · FY2017 · MH · contact PI
Illuminating the druggable GPCR-ome$2,301,310
U24 · FY2017 · DK · contact PI
Structure-Function of Opioid Receptors$1,391,835
P01 · FY2017 · DA
Structural Studies of Opioid Receptors, p 55$792,420
P01 · FY2017 · DA
Molecular Details of Psychoactive Drug Actions$646,715
R01 · FY2017 · MH · contact PI
Opioid Receptor Protein Production Core$327,065
P01 · FY2017 · DA
Structure-Based Discovery Opioid Receptor Ligands and Molecules, p. 83$148,996
P01 · FY2017 · DA
Management and Administration Core, p. 192$123,354
P01 · FY2017 · DA
NIMH Psychoactive Drug Screening Program$2,668,047
N01 · FY2016 · MH · contact PI
Functional Selectivity: A Novel Approach for CNS Drug Discovery$1,527,521
U19 · FY2016 · MH · contact PI
Structure-Function of Opioid Receptors$1,377,916
P01 · FY2016 · DA
DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT$943,003
U01 · FY2016 · MH · contact PI
Structural Studies of Opioid Receptors, p 55$784,494
P01 · FY2016 · DA
Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia$659,346
R01 · FY2016 · MH
Scalable technologies for illuminating the druggable GPCR-ome$396,932
U01 · FY2016 · MH · contact PI
Opioid Receptor Protein Production Core$323,795
P01 · FY2016 · DA
Screening Core$284,825
U19 · FY2016 · MH · contact PI
DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT$198,768
U01 · FY2016 · MH · contact PI
Structure-Based Discovery Opioid Receptor Ligands and Molecules, p. 83$147,505
P01 · FY2016 · DA
Management and Administration Core, p. 192$122,122
P01 · FY2016 · DA
Administrative Core$41,829
U19 · FY2016 · MH · contact PI
NIMH Psychoactive Drug Screening Program$2,594,835
N01 · FY2015 · MH · contact PI
Functional Selectivity: A Novel Approach for CNS Drug Discovery$1,527,521
U19 · FY2015 · MH · contact PI
Structure-Function of Opioid Receptors$1,370,342
P01 · FY2015 · DA
DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT$908,902
U01 · FY2015 · MH · contact PI
Structural Studies of Opioid Receptors, p 55$780,359
P01 · FY2015 · DA
Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia$670,441
R01 · FY2015 · MH
Scalable technologies for illuminating the druggable GPCR-ome$396,932
U01 · FY2015 · MH · contact PI
Opioid Receptor Protein Production Core$321,913
P01 · FY2015 · DA
Screening Core$284,825
U19 · FY2015 · MH · contact PI
Scalable technologies for illuminating the druggable GPCR-ome$213,200
U01 · FY2015 · MH · contact PI
Structure-Based Discovery Opioid Receptor Ligands and Molecules, p. 83$146,651
P01 · FY2015 · DA
Management and Administration Core, p. 192$121,419
P01 · FY2015 · DA
Administrative Core$41,829
U19 · FY2015 · MH · contact PI
NIMH Psychoactive Drug Screening Program$2,546,582
N01 · FY2014 · MH · contact PI
Structure-Function of Opioid Receptors$1,531,889
P01 · FY2014 · DA
Functional Selectivity: A Novel Approach for CNS Drug Discovery$1,527,521
U19 · FY2014 · MH · contact PI
DREADD2.0: AN ENHANCED CHEMOGENETIC TOOLKIT$997,398
U01 · FY2014 · MH · contact PI
Structural Studies of Opioid Receptors, p 55$844,634
P01 · FY2014 · DA
Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia$682,841
R01 · FY2014 · MH
Scalable technologies for illuminating the druggable GPCR-ome$409,548
U01 · FY2014 · MH · contact PI
Opioid Receptor Protein Production Core$375,629
P01 · FY2014 · DA
Targeting and Trafficking of 5-HT2A Serotonin Receptors$363,449
R01 · FY2014 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$323,294
R01 · FY2014 · DA · contact PI
Screening Core$284,825
U19 · FY2014 · MH · contact PI
Structure-Based Discovery Opioid Receptor Ligands and Molecules, p. 83$171,119
P01 · FY2014 · DA
Management and Administration Core, p. 192$140,507
P01 · FY2014 · DA
Administrative Core$41,829
U19 · FY2014 · MH · contact PI
Functional Selectivity: A Novel Approach for CNS Drug Discovery$1,466,420
U19 · FY2013 · MH · contact PI
Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia$798,394
R01 · FY2013 · MH
Targeting and Trafficking of 5-HT2A Serotonin Receptors$348,911
R01 · FY2013 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$310,362
R01 · FY2013 · DA · contact PI
Screening Core$273,432
U19 · FY2013 · MH · contact PI
Administrative Core$40,157
U19 · FY2013 · MH · contact PI
NIMH Psychoactive Drug Screening Program$2,297,124
N01 · FY2012 · MH · contact PI
Functional Selectivity: A Novel Approach for CNS Drug Discovery$1,661,716
U19 · FY2012 · MH · contact PI
Targeting and Trafficking of 5-HT2A Serotonin Receptors$363,449
R01 · FY2012 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$323,294
R01 · FY2012 · DA · contact PI
Screening Core$316,473
U19 · FY2012 · MH · contact PI
Deorphanizing the Peptidome$286,650
R01 · FY2012 · DA
Administrative Core$46,477
U19 · FY2012 · MH · contact PI
NIMH Psychoactive Drug Screening Program$2,233,037
N01 · FY2011 · MH · contact PI
Functional Selectivity: A Novel approach for CNS Drug Discovery$1,623,361
U19 · FY2011 · MH · contact PI
Targeting and Trafficking of 5-HT2A Serotonin Receptors$363,449
R01 · FY2011 · MH · contact PI
PROJECT 1: ROTH: Functionally Selective Antagonists and Engineered Receptors$357,587
U19 · FY2011 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$323,294
R01 · FY2011 · DA · contact PI
Deorphanizing the Peptidome$286,650
R01 · FY2011 · DA
ADMINISTRATIVE CORE$57,652
U19 · FY2011 · MH · contact PI
NIMH Psychoactive Drug Screening Program$3,314,560
N01 · FY2010 · MH · contact PI
Functional Selectivity: A Novel approach for CNS Drug Discovery$1,653,900
U19 · FY2010 · MH · contact PI
Targeting and Trafficking of 5-HT2A Serotonin Receptors$367,120
R01 · FY2010 · MH · contact PI
PROJECT 1: ROTH: Functionally Selective Antagonists and Engineered Receptors$361,200
U19 · FY2010 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$358,037
R01 · FY2010 · DA · contact PI
Functional Selectivity: A Novel Approach for CNS Drug Discovery$325,784
U19 · FY2010 · MH · contact PI
Deorphanizing the Peptidome$295,515
R01 · FY2010 · DA
ADMINISTRATIVE CORE$58,235
U19 · FY2010 · MH · contact PI
Opportunities for Innovative Drug Development for Schizophrenia$49,250
R13 · FY2010 · MH
NIMH Psychoactive Drug Screening Program$2,093,318
N01 · FY2009 · MH · contact PI
Functional Selectivity: A Novel approach for CNS Drug Discovery$1,298,931
U19 · FY2009 · MH · contact PI
PROJECT 1: ROTH: Functionally Selective Antagonists and Engineered Receptors$353,739
U19 · FY2009 · MH · contact PI
Targeting and Trafficking of 5-HT2A serotonin Receptors$346,086
R01 · FY2009 · MH · contact PI
Deorphanizing the Peptidome$311,500
R01 · FY2009 · DA
ADMINISTRATIVE CORE$56,536
U19 · FY2009 · MH · contact PI
Opportunities for Innovative Drug Development for Schizophrenia$50,000
R13 · FY2009 · MH
Functional Selectivity: A Novel approach for CNS Drug Discovery$1,264,814
U19 · FY2008 · MH · contact PI
Targeting and Trafficking of 5-HT2A serotonin Receptors$346,086
R01 · FY2008 · MH · contact PI
PROJECT 1: ROTH: Functionally Selective Antagonists and Engineered Receptors$340,464
U19 · FY2008 · MH · contact PI
ADMINISTRATIVE CORE$54,889
U19 · FY2008 · MH · contact PI
CORE 3: RAT ANTIPSYCH. DRUG TESTING CORE$3
U19 · FY2008 · MH · contact PI
NIMH PSYCHOACTIVE DRUG SCREENING PROGRAM$2,109,685
N01 · FY2007 · MH · contact PI
Functional Selectivity: A Novel approach for CNS Drug Discovery$1,328,482
U19 · FY2007 · MH · contact PI
Targeting and Trafficking of 5-HT2A serotonin Receptors$346,086
R01 · FY2007 · MH · contact PI
PROJECT 1: ROTH: Functionally Selective Antagonists and Engineered Receptors$342,660
U19 · FY2007 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$280,661
R01 · FY2007 · DA · contact PI
CORE 1: ADMINISTRATIVE CORE (ROTH)$57,435
U19 · FY2007 · MH · contact PI
PSD-95 MODULATES 5-HT2A AND 5-HT2C RECEPTOR FUNCTION IN VIVO$5,285
P51 · FY2007 · RR · contact PI
CORE 3: RAT ANTIPSYCH. DRUG TESTING CORE$1
U19 · FY2007 · MH · contact PI
Diterpines as Selective Kappa Opioid Receptor Agonists$311,504
R01 · FY2006 · DA · contact PI
Targeting and Trafficking of 5-HT2A serotonin Receptors$267,516
R01 · FY2006 · MH · contact PI
Structural Domains Essential for Serotonin Receptor Pharmacology$151,834
R01 · FY2006 · MH · contact PI
Structural Domains Essential for Serotonin Receptor Pharmacology$115,527
R01 · FY2006 · MH · contact PI
Targeting and Trafficking of 5-HT2A serotonin Receptors$105,995
R01 · FY2006 · MH · contact PI
Structural Domains Essential for Serotonin Receptor Pharmacology$353,122
R01 · FY2005 · MH
Targeting and Trafficking of 5-HT2A serotonin Receptors$344,250
R01 · FY2005 · MH
Diterpines as Selective Kappa Opioid Receptor Agonists$303,000
R01 · FY2005 · DA
Molecular Mechanisms of 5-HT Receptor Actions$118,584
K02 · FY2005 · MH
Structural Domains Essential for Serotonin Receptor Pharmacology$349,839
R01 · FY2004 · MH
Diterpines as Selective Kappa Opioid Receptor Agonists$303,000
R01 · FY2004 · DA
Molecular Mechanisms of 5-HT Receptor Actions$118,584
K02 · FY2004 · MH
Diterpines as Selective Kappa Opioid Receptor Agonists$356,000
R01 · FY2003 · DA
Structural Domains Essential for Serotonin Receptor Pharmacology$267,750
R01 · FY2003 · MH
REGULATION OF 5HT2A RECEPTOR TRAFFICKING$229,500
R01 · FY2003 · MH
Molecular Mechanisms of 5-HT Receptor Actions$118,584
K02 · FY2003 · MH
Structural Domains Essential for Serotonin Receptor Pharmacology$45,977
R01 · FY2003 · MH
Structural Domains for Serotonin Receptor Pharmacology$267,750
R01 · FY2002 · MH
REGULATION OF 5HT2A RECEPTOR TRAFFICKING$229,500
R01 · FY2002 · MH
Molecular Mechanisms of 5-HT Receptor Actions$118,584
K02 · FY2002 · MH
REGULATION OF 5HT2A RECEPTOR TRAFFICKING$229,500
R01 · FY2001 · MH
Molecular Mechanisms of 5HT Receptor Actions$118,584
K02 · FY2001 · MH
NIMH PSYCHOACTIVE DRUG SCREENING PROGRAM$892,302
N01 · FY2000 · MH
STRUCTURAL DOMAINS FOR SEROTONIN RECEPTOR PHARMACOLOGY$261,270
R01 · FY2000 · MH
REGULATION OF 5HT2A RECEPTOR TRAFFICKING$229,500
R01 · FY2000 · MH
MOLECULAR MECHANISMS OF 5-HT RECEPTOR ACTIONS$101,250
K02 · FY2000 · MH