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Stephen Vernon Frye

Univ Of North Carolina Chapel Hill

$8,267,632
Attributed
$9,030,407
Total exposure
10
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $8.6M · FY200925
$10M$7.5M$5M$2.5M$0
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$31,261,316 · 11

By mechanism

U54$22,230,909 · 1
R01$4,366,688 · 2
R35$2,086,611 · 1
RC1$875,802 · 1
R21$813,520 · 2
R41$712,031 · 2

Top collaborators

Most similar at Univ Of North Carolina Chapel Hill

Same institution · by research overlap

Others in their field

Top investigators on “Proteins

Research focus

ProteinsBiologySmall MoleculeValidationCellsBaseInterestDrug DiscoveryComplexDesignCommunitiesIn VivoProgramsRegulationLysineHistonesChromatinReaderStructureHistone ModificationFutureBiologicalAnimal ModelGenome

Grant awards (33)

PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS$383,255
R35 · FY2025 · GM · contact PI
PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS$425,839
R35 · FY2024 · GM · contact PI
Molecular Therapeutics Research Program$40,560
P30 · FY2024 · CA · contact PI
PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS$425,839
R35 · FY2023 · GM · contact PI
Molecular Therapeutics Research Program$45,065
P30 · FY2023 · CA · contact PI
PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS$425,839
R35 · FY2022 · GM · contact PI
Molecular Therapeutics Research Program$45,065
P30 · FY2022 · CA · contact PI
Open Drug Discovery Center for Alzheimer's Disease$7,311,958
U54 · FY2021 · AG
PROBING ALLOSTERY IN METHYL-LYSINE READER DOMAINS$425,839
R35 · FY2021 · GM · contact PI
Molecular Therapeutics Research Program$45,065
P30 · FY2021 · CA · contact PI
Open Drug Discovery Center for Alzheimer's Disease$7,420,073
U54 · FY2020 · AG
DISCOVERY OF IN VIVO CHEMICAL PROBES FOR POLYCOMB CBX DOMAINS$520,558
R01 · FY2020 · CA · contact PI
Open Drug Discovery Center for Alzheimer's Disease$7,498,878
U54 · FY2019 · AG
DISCOVERY OF IN VIVO CHEMICAL PROBES FOR POLYCOMB CBX DOMAINS$504,942
R01 · FY2019 · CA · contact PI
Discovery of Chemical Probes for Chromatin Readers$416,687
R01 · FY2019 · GM · contact PI
Modulating the DNA methylation program through UHRF1 antagonism$172,680
R21 · FY2019 · CA · contact PI
DISCOVERY OF IN VIVO CHEMICAL PROBES FOR POLYCOMB CBX DOMAINS$456,482
R01 · FY2018 · CA · contact PI
Discovery of Chemical Probes for Chromatin Readers$416,687
R01 · FY2018 · GM · contact PI
Modulating the DNA methylation program through UHRF1 antagonism$223,654
R21 · FY2018 · CA · contact PI
Developing therapeutic inhibitors of CIB1 for breast cancer$100,000
R41 · FY2018 · CA · contact PI
Discovery of Chemical Probes for Chromatin Readers$90,000
R01 · FY2018 · GM · contact PI
Discovery of Chemical Probes for Chromatin Readers$416,687
R01 · FY2017 · GM · contact PI
Discovery of Chemical Probes for Chromatin Readers$429,687
R01 · FY2016 · GM · contact PI
Development of Small Molecules that Enhance the Delivery and the Pharmacological Effects of Oligonucleotides$312,031
R41 · FY2015 · TR
Developing therapeutic inhibitors of CIB1 for breast cancer$300,000
R41 · FY2015 · CA · contact PI
DISCOVERY OF CHEMICAL PROBES FOR METHYL-LYSINE READERS$281,200
R01 · FY2015 · GM · contact PI
Targeting SecA1 of Mycobacterium tuberculosis for Novel Drug Development$230,399
R21 · FY2015 · AI
DISCOVERY OF CHEMICAL PROBES FOR METHYL-LYSINE READERS$281,200
R01 · FY2014 · GM · contact PI
Targeting SecA1 of Mycobacterium tuberculosis for Novel Drug Development$186,787
R21 · FY2014 · AI
DISCOVERY OF CHEMICAL PROBES FOR METHYL-LYSINE READERS$271,358
R01 · FY2013 · GM · contact PI
DISCOVERY OF CHEMICAL PROBES FOR METHYL-LYSINE READERS$281,200
R01 · FY2012 · GM · contact PI
Discovery of Small Molecule MBT Domain Antagonists$441,607
RC1 · FY2010 · GM · contact PI
Discovery of Small Molecule MBT Domain Antagonists$434,195
RC1 · FY2009 · GM · contact PI