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Damian J Krysan

University Of Iowa

$18,418,332
Attributed
$24,451,552
Total exposure
16
Grants
15
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.2M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$24,451,552 · 16

By mechanism

R01$21,495,258 · 9
R21$2,589,226 · 6
K08$367,068 · 1

Top collaborators

Most similar at University Of Iowa

Same institution · by research overlap

Others in their field

Top investigators on “Affect

Research focus

AffectBaseInfectionCandida AlbicansIn VitroMutantPathogenLibrariesPathogenesisIn VivoYeastsLeadMouse ModelLifeGenesPharmaceutical PreparationsGeneticDesignPathway InteractionsPathogenic FungusCellsCryptococcus NeoformansVirulencePersons

Grant awards (54)

Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$2,811,266
R01 · FY2025 · AI · contact PI
Regulation of Candida albicans Pathogenesis by Protein Kinase and Transcription Factor Networks$739,862
R01 · FY2025 · AI · contact PI
Discovery and optimization of antifungal acetyl CoA synthetase inhibitors$627,320
R01 · FY2025 · AI · contact PI
Regulation of Candida albicans Pathogenesis by Protein Kinase and Transcription Factor Networks$751,293
R01 · FY2024 · AI · contact PI
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$630,827
R01 · FY2024 · AI · contact PI
Discovery and optimization of antifungal acetyl CoA synthetase inhibitors$627,320
R01 · FY2024 · AI · contact PI
Systematic Genetic Analysis of C. albicans CNS Infection$234,319
R21 · FY2024 · AI · contact PI
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$630,827
R01 · FY2023 · AI · contact PI
Discovery and optimization of antifungal acetyl CoA synthetase inhibitors$591,506
R01 · FY2023 · AI · contact PI
Systematic Genetic Analysis of C. albicans CNS Infection$209,319
R21 · FY2023 · AI · contact PI
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$663,532
R01 · FY2022 · AI · contact PI
Discovery and optimization of antifungal acetyl CoA synthetase inhibitors$593,558
R01 · FY2022 · AI · contact PI
Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis$415,075
R01 · FY2022 · AI · contact PI
Systematic in vitro and in vivo genetic analysis of C.albicans protein kinases$191,874
R21 · FY2022 · AI · contact PI
Hit-to-lead optimization of broad spectrum antifungal phenothiazines$190,875
R21 · FY2022 · AI · contact PI
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$678,567
R01 · FY2021 · AI · contact PI
Discovery and optimization of antifungal acetyl CoA synthetase inhibitors$599,458
R01 · FY2021 · AI · contact PI
Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis$414,829
R01 · FY2021 · AI · contact PI
Systematic in vitro and in vivo genetic analysis of C.albicans protein kinases$244,071
R21 · FY2021 · AI · contact PI
Hit-to-lead optimization of broad spectrum antifungal phenothiazines$243,125
R21 · FY2021 · AI · contact PI
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis$683,782
R01 · FY2020 · AI · contact PI
Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis$540,362
R01 · FY2020 · AI · contact PI
Targeting Hsp90 in cryptococcal fungal pathogenesis$777,729
R01 · FY2019 · AI
Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis$571,858
R01 · FY2019 · AI · contact PI
Targeting Hsp90 in cryptococcal fungal pathogenesis$796,231
R01 · FY2018 · AI
Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis$517,953
R01 · FY2018 · AI · contact PI
Targeting Hsp90 in cryptococcal fungal pathogenesis$817,242
R01 · FY2017 · AI
Characterization of Activity and Mechanism of Novel Fungicidal Anti-Cryptococcal Molecules$113,233
R21 · FY2017 · AI · contact PI
Characterization of activity and mechanism of novel fungicidal anti-cryptococcal molecules$77,946
R21 · FY2017 · AI · contact PI
Large scale synthetic genetic analysis in Candida albicans$387,319
R01 · FY2016 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$309,244
R01 · FY2016 · AI · contact PI
Characterization of activity and mechanism of novel fungicidal anti-cryptococcal molecules$230,250
R21 · FY2016 · AI · contact PI
Genetic screen for fungal triggers of the NLRP-3-inflammasone in macrophages$189,381
R21 · FY2016 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$74,481
R01 · FY2016 · AI · contact PI
Large scale synthetic genetic analysis in Candida albicans$387,293
R01 · FY2015 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$386,250
R01 · FY2015 · AI · contact PI
Genetic screen for fungal triggers of the NLRP-3-inflammasone in macrophages$241,437
R21 · FY2015 · AI · contact PI
Large scale synthetic genetic analysis in Candida albicans$387,270
R01 · FY2014 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$386,250
R01 · FY2014 · AI · contact PI
Large scale synthetic genetic analysis in Candida albicans$364,010
R01 · FY2013 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$363,075
R01 · FY2013 · AI · contact PI
Large scale synthetic genetic analysis in Candida albicans$400,848
R01 · FY2012 · AI · contact PI
Phosphoinositide-dependent kinase-1 as an antifungal drug target$386,250
R01 · FY2012 · AI · contact PI
Discovery and evaluation of fungicidal anti-cryptococcal molecules$382,731
R01 · FY2012 · AI · contact PI
Discovery and evaluation of fungicidal anti-cryptococcal molecules$377,336
R01 · FY2011 · AI · contact PI
Chemical Genetic HTS Assay for Inhibitors of Fungal Cell Wall Integrity$339,605
R01 · FY2011 · AI · contact PI
Discovery and evaluation of fungicidal anti-cryptococcal molecules$393,364
R01 · FY2010 · AI · contact PI
Chemical Genetic HTS Assay for Inhibitors of Fungal Cell Wall Integrity$343,035
R01 · FY2010 · AI · contact PI
Synthetic Genetic Analysis of the RAM network in C. albicans$230,567
R21 · FY2010 · AI · contact PI
Chemical Genetic HTS Assay for Inhibitors of Fungal Cell Wall Integrity$346,500
R01 · FY2009 · AI · contact PI
Synthetic Genetic Analysis of the RAM network in C. albicans$192,829
R21 · FY2009 · AI · contact PI
Yeast Aspartyl Proteases in Cell Wall Integrity$122,356
K08 · FY2007 · AI · contact PI
Yeast Aspartyl Proteases in Cell Wall Integrity$122,356
K08 · FY2006 · AI · contact PI
Yeast Aspartyl Proteases in Cell Wall Integrity$122,356
K08 · FY2005 · AI