← Leaderboards
Thomas J Begley
Massachusetts Institute Of Technology
$14,062,480
Attributed
$16,644,698
Total exposure
14
Grants
11
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $1.5M · FY2005–25$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$16,644,698 · 14
By mechanism
R01$13,137,381 · 6
T32$1,482,039 · 1
R21$1,287,424 · 3
R41$350,000 · 1
K22$315,122 · 1
F32$64,732 · 1
Top collaborators
- Marlene Belfort5 shared
- Peter C Dedon4 shared
- Jia Sheng4 shared
- Julio A Aguirre-Ghiso2 shared
- Shane Byrne1 shared
Most similar at Massachusetts Institute Of Technology
Same institution · by research overlap
- Peter C Dedon$29,387,499
- Richard J Temkin$17,385,032
Others in their field
Top investigators on “Response”
- Lawrence Corey · Fred Hutchinson Cancer Center$677,505,141
- David Divins · Consortium For Ocean Leadership, Inc$609,772,544
- Margaret Juliana McElrath · Fred Hutchinson Cancer Center$532,027,174
- Barton F Haynes · Duke University$497,761,007
- Jeffrey P Krischer · University Of South Florida$397,532,270
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$342,310,423
Research focus
ResponseCellsProteinsModificationTransfer RnaCodon NucleotidesGenesStressTranslationsDna DamageEnzymesTranscriptProgramsYeastsLinkIn VivoSignal TransductionInsightBiological Adaptation To StressBasePatternGene ExpressionExposure ToPlay
Grant awards (57)
Translational regulation in exposure biology - Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$443,065
R01 · FY2025 · ES · contact PI
RNA Science and Technology in Health and Disease$360,802
T32 · FY2025 · GM · contact PI
Chemical Modifications to Wobble Uridines in tRNA Regulate Responses to Stress$358,805
R01 · FY2025 · GM
Translational regulation in exposure biology - Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$446,906
R01 · FY2024 · ES · contact PI
Translational regulation during cigarette smoking-induced reprogramming of the tRNA epitranscriptome, in vitro and in a mouse smoking model$377,990
R01 · FY2024 · ES · contact PI
Chemical Modifications to Wobble Uridines in tRNA Regulate Responses to Stress$358,805
R01 · FY2024 · GM
Optimizing Antibody Production in CHO Cells Using Epi-MAX Technology to Increase Heavy and Light Chain Expression$350,000
R41 · FY2024 · TR
Translational regulation in exposure biology - Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$449,561
R01 · FY2023 · ES · contact PI
Translational regulation during cigarette smoking-induced reprogramming of the tRNA epitranscriptome, in vitro and in a mouse smoking model$377,990
R01 · FY2023 · ES · contact PI
Chemical Modifications to Wobble Uridines in tRNA Regulate Responses to Stress$358,622
R01 · FY2023 · GM
RNA Science and Technology in Health and Disease$215,175
T32 · FY2023 · GM · contact PI
Translational regulation in exposure biology - Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$465,482
R01 · FY2022 · ES · contact PI
Translational regulation during cigarette smoking-induced reprogramming of the tRNA epitranscriptome, in vitro and in a mouse smoking model$377,990
R01 · FY2022 · ES · contact PI
Chemical Modifications to Wobble Uridines in tRNA Regulate Responses to Stress$357,706
R01 · FY2022 · GM
RNA Science and Technology in Health and Disease$273,817
T32 · FY2022 · GM · contact PI
Translational regulation during cigarette smoking-induced reprogramming of the tRNA epitranscriptome, in vitro and in a mouse smoking model$377,990
R01 · FY2021 · ES · contact PI
RNA Science and Technology in Health and Disease$257,627
T32 · FY2021 · GM · contact PI
Translational regulation during cigarette smoking-induced reprogramming of the tRNA epitranscriptome, in vitro and in a mouse smoking model$405,240
R01 · FY2020 · ES · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodels$333,101
R01 · FY2020 · ES · contact PI
RNA Science and Technology in Health and Disease$250,834
T32 · FY2020 · GM · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodels$333,024
R01 · FY2019 · ES · contact PI
RNA Science and Technology in Health and Disease$123,784
T32 · FY2019 · GM · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodels$334,048
R01 · FY2018 · ES · contact PI
Translational Control of ROS Management$327,935
R01 · FY2018 · ES · contact PI
Translational control of ROS Management$327,415
R01 · FY2017 · ES · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodels$307,414
R01 · FY2017 · ES · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$46,948
R01 · FY2017 · ES · contact PI
Translational control of ROS Management$387,345
R01 · FY2016 · ES · contact PI
Translational regulation in exposure biology: Xenobiotic-induced reprograming of tRNA modifications and selective translation of codon-biased response genes in rat and human models$337,360
R01 · FY2016 · ES · contact PI
Translational control of ROS Management$326,035
R01 · FY2015 · ES · contact PI
Translational control of ROS Management$63,654
R01 · FY2015 · ES · contact PI
Translational control of ROS Management$336,865
R01 · FY2014 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$346,673
R01 · FY2013 · ES · contact PI
Targeted Degradation of DNA Damage Response Proteins by Autophagy$186,200
R21 · FY2013 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$74,988
R01 · FY2013 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$447,195
R01 · FY2012 · ES · contact PI
Targeted Degradation of DNA Damage Response Proteins by Autophagy$228,000
R21 · FY2012 · ES · contact PI
Multiplexed Quantification of DNA Damage Response$146,388
R21 · FY2012 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$444,111
R01 · FY2011 · ES · contact PI
Multiplexed Quantification of DNA Damage Response$272,588
R21 · FY2011 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$355,637
R01 · FY2010 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$348,071
R01 · FY2010 · ES · contact PI
Translational Machinery in Stress Signaling and Tumor Suppression$200,626
R21 · FY2010 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$89,935
R01 · FY2010 · ES · contact PI
RNA Modifications as Biomarkers of Environmental Stress and Inflammation$370,283
R01 · FY2009 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$351,588
R01 · FY2009 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$345,244
R01 · FY2009 · ES · contact PI
Translational Machinery in Stress Signaling and Tumor Suppression$253,622
R21 · FY2009 · ES · contact PI
Systems Level Understanding of DNA Damage Responses$8,000
R13 · FY2009 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$351,588
R01 · FY2008 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$506,735
R01 · FY2007 · ES · contact PI
The Roles of Trm9 and tRNA Methylation in the DNA Damage Response$488,037
R01 · FY2006 · ES · contact PI
PROTEIN INTERACTION NETWORKS IN DNA REPAIR$105,462
K22 · FY2006 · ES · contact PI
PROTEIN INTERACTION NETWORKS IN DNA REPAIR$104,684
K22 · FY2005 · ES
PROTEIN INTERACTION NETWORKS IN DNA REPAIR$104,976
K22 · FY2004 · ES
Toxicogenomic Approaches to Study Alkylation Resistance$20,520
F32 · FY2003 · ES
Toxicogenomic Approaches to Study Alkylation Resistance$44,212
F32 · FY2002 · ES