← Leaderboards
Douglas J Sheffler
Case Western Reserve University
$5,597,870
Attributed
$6,910,433
Total exposure
4
Grants
2
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $1.8M · FY2019–25$2M$1.5M$1M$500K$0
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$6,910,433 · 4
By mechanism
R01$4,873,439 · 2
U43$1,968,844 · 1
F31$68,150 · 1
Top collaborators
- Reto Andreas Gadient2 shared
- Robert Warren Gould2 shared
Most similar at Case Western Reserve University
Same institution · by research overlap
- Evan S Deneris$18,140,872
- Kenneth J Gustafson$1,661,127
- Peter F Buckley$1,987,121
- Jaclene A Zauszniewski$7,130,804
- Seong Sung Shim$138,556
Others in their field
Top investigators on “Small Molecule”
- David Heimbrook · Leidos Biomedical Research, Inc.$251,072,489
- Douglas S. Hawkins · Children'S Hosp Of Philadelphia$157,315,120
- Peter C Adamson · National Childhood Cancer Foundation$143,645,434
- Mark S Klempner · Tufts Medical Center$128,021,180
- Stuart L Schreiber · Harvard University (Medical School)$79,067,419
- Edward A Dennis · University Of California, San Diego$73,030,813
Research focus
Small MoleculeRodent ModelNaltrexoneMedicalRattusCause Of DeathDisulfiramEffective TherapyEthanol DependenceIn VivoPharmaceutical PreparationsPlayAffectAlcoholsCessation Of LifeAlcohol Use DisorderDrug KineticsDown-RegulationAmygdaloid StructureAlcohol ConsumptionAdultGlutamatesAcamprosateStress
Grant awards (10)
Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder$786,961
R01 · FY2025 · AA · contact PI
Preclinical validation of mGlu2 PAMs in alcohol use disorder$994,906
U43 · FY2024 · AA
Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder$800,043
R01 · FY2024 · AA · contact PI
Preclinical validation of mGlu2 PAMs in alcohol use disorder$973,938
U43 · FY2023 · AA
Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use Disorder$851,142
R01 · FY2023 · AA · contact PI
Lead optimization of novel CRFBP-CRFR2 complex modulators for alcohol use disorder$733,411
R01 · FY2021 · AA · contact PI
Lead optimization of novel CRFBP-CRFR2 complex modulators for alcohol use disorder$836,039
R01 · FY2020 · AA · contact PI
Lead optimization of novel CRFBP-CRFR2 complex modulators for alcohol use disorder$865,843
R01 · FY2019 · AA · contact PI
Interaction of RSK2 with 5-HT2A receptor$35,383
F31 · FY2004 · MH
Interaction of RSK2 with 5-HT2A receptor$32,767
F31 · FY2002 · MH