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Lawrence Shapiro

Columbia University Health Sciences

$30,150,508
Attributed
$35,212,203
Total exposure
22
Grants
19
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $7.1M · FY200523
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23

Funding mix

By agency

NIH$35,212,203 · 22

By mechanism

R01$19,677,059 · 9
U54$6,773,313 · 3
U19$5,326,632 · 1
P01$2,116,846 · 1
P30$1,247,650 · 3
P41$70,703 · 5

Top collaborators

Most similar at Columbia University Health Sciences

Same institution · by research overlap

Others in their field

Top investigators on “Base

Research focus

BaseStructureMolecularProteinsMediatingComplexCellsCadherinsReconstructionMapsMutantMutationResolutionDesignAffinityBindingCrystallographySurfaceFundingCell AdhesionMutagenesisPropertyAdhesivesMembrane

Grant awards (84)

Structure and mechanism of the protein-capture receptors of the kidney proximal tubule$631,431
R01 · FY2023 · DK · contact PI
Structural Biology and Computational Modeling Core$5,326,632
U19 · FY2022 · AI · contact PI
Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness$647,665
R01 · FY2022 · DC · contact PI
Structure and mechanism of the protein-capture receptors of the kidney proximal tubule$631,410
R01 · FY2022 · DK · contact PI
Structure and mechanism of pemphigus autoantibodies$487,197
R01 · FY2022 · AR · contact PI
Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness$647,665
R01 · FY2021 · DC · contact PI
Structure and mechanism of the protein-capture receptors of the kidney proximal tubule$631,377
R01 · FY2021 · DK · contact PI
The structural basis of cis and trans protocadherin interactions$480,094
R01 · FY2021 · MH
Structure and mechanism of pemphigus autoantibodies$477,355
R01 · FY2021 · AR · contact PI
Structure and mechanism of the protein-capture receptors of the kidney proximal tubule$674,223
R01 · FY2020 · DK · contact PI
Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness$648,310
R01 · FY2020 · DC · contact PI
Structure and mechanism of pemphigus autoantibodies$492,118
R01 · FY2020 · AR · contact PI
The structural basis of cis and trans protocadherin interactions$480,094
R01 · FY2020 · MH
Structure and Function of Desmosomal Cadherins$447,858
R01 · FY2020 · GM · contact PI
Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness$649,303
R01 · FY2019 · DC · contact PI
Structure and mechanism of pemphigus autoantibodies$492,118
R01 · FY2019 · AR · contact PI
The structural basis of cis and trans protocadherin interactions$480,094
R01 · FY2019 · MH
Structure and Function of Desmosomal Cadherins$447,858
R01 · FY2019 · GM · contact PI
Integrative Structural and Functional Characterization of Tip-Link Cadherins Deafness$716,205
R01 · FY2018 · DC · contact PI
The structural basis of cis and trans protocadherin interactions$480,094
R01 · FY2018 · MH
Structure and Function of Desmosomal Cadherins$447,858
R01 · FY2018 · GM · contact PI
Structure and mechanism of pemphigus autoantibodies$440,658
R01 · FY2018 · AR · contact PI
The structural basis of cis and trans protocadherin interactions$480,094
R01 · FY2017 · MH
Structure and Function of Desmosomal Cadherins$462,858
R01 · FY2017 · GM · contact PI
Bioinformatics and Structure$207,590
P01 · FY2017 · AI · contact PI
Bioinformatics and Structure$616,755
P01 · FY2016 · AI · contact PI
The structural basis of cis and trans protocadherin interactions$460,304
R01 · FY2016 · GM
Bioinformatics and Structure$616,732
P01 · FY2015 · AI · contact PI
The structural basis of cis and trans protocadherin interactions$461,003
R01 · FY2015 · GM
Molecular basis of Cadherin Mediated Cell Adhesion$321,405
R01 · FY2015 · GM · contact PI
Bioinformatics and Structure$675,769
P01 · FY2014 · AI · contact PI
The structural basis of cis and trans protocadherin interactions$461,682
R01 · FY2014 · GM
Fluorescence methods for HT validation and production of protein complexes$322,000
R01 · FY2014 · GM · contact PI
Molecular basis of Cadherin Mediated Cell Adhesion$321,405
R01 · FY2014 · GM · contact PI
Structural Genomics and Membrane Proteins$125,817
U54 · FY2014 · GM · contact PI
The structural basis of cis and trans protocadherin interactions$462,343
R01 · FY2013 · GM
Fluorescence methods for HT validation and production of protein complexes$310,730
R01 · FY2013 · GM · contact PI
Molecular basis of Cadherin Mediated Cell Adhesion$310,156
R01 · FY2013 · GM · contact PI
Structural Genomics and Membrane Proteins$138,466
U54 · FY2013 · GM · contact PI
PROTEOMICS RESOURCE$136,392
P30 · FY2013 · CA · contact PI
Fluorescence methods for HT validation and production of protein complexes$322,000
R01 · FY2012 · GM · contact PI
Molecular basis of Cadherin Mediated Cell Adhesion$321,405
R01 · FY2012 · GM · contact PI
Structural Genomics and Membrane Proteins$154,908
U54 · FY2012 · GM · contact PI
PROTEOMICS RESOURCE$76,315
P30 · FY2012 · CA · contact PI
Fluorescence methods for HT validation and production of protein complexes$322,000
R01 · FY2011 · GM · contact PI
Molecular Basis of Cadherin Mediated Cell Adhesion$294,326
R01 · FY2011 · GM · contact PI
Structural Genomics and Membrane Proteins$143,087
U54 · FY2011 · GM · contact PI
PROTEOMICS RESOURCE$85,216
P30 · FY2011 · CA · contact PI
INTERCELLULAR ADHESION PROTEINS$11,187
P41 · FY2011 · RR · contact PI
Structure and mechanism of the AMP-activated protein kinase$316,605
R01 · FY2010 · DK · contact PI
Molecular Basis of Cadherin Mediated Cell Adhesion$297,299
R01 · FY2010 · GM · contact PI
Structural Genomics and Membrane Proteins$148,736
U54 · FY2010 · GM · contact PI
PROTEOMICS RESOURCE$87,031
P30 · FY2010 · CA · contact PI
Structure and mechanism of the AMP-activated protein kinase$315,378
R01 · FY2009 · DK · contact PI
Molecular Basis of Cadherin Mediated Cell Adhesion$300,302
R01 · FY2009 · GM · contact PI
Sub 6 at Columbia$242,652
U54 · FY2009 · GM · contact PI
PROTEOMICS RESOURCE$86,660
P30 · FY2009 · CA · contact PI
STRUCTURAL STUDIES OF CELL ADHESION PROTEINS$8,556
P41 · FY2009 · RR · contact PI
PROTEOMICS RESOURCE$1,057
P30 · FY2009 · CA · contact PI
SUBPROJECT 3$1,445,779
U54 · FY2008 · GM · contact PI
SUBPROJECT 3$1,429,305
U54 · FY2008 · GM · contact PI
Molecular Basis of Cadherin Mediated Cell Adhesion$300,302
R01 · FY2008 · GM · contact PI
Sub 6 at Columbia$235,002
U54 · FY2008 · GM · contact PI
PROTEOMICS RESOURCE$52,743
P30 · FY2008 · CA · contact PI
CADHERIN CELL ADHESION PROTEINS$14,112
P41 · FY2008 · RR · contact PI
SUBPROJECT 3$1,418,726
U54 · FY2007 · GM · contact PI
Sub 6 at Columbia$234,549
U54 · FY2007 · GM · contact PI
SUBPROJECT 3$360,719
U54 · FY2006 · GM · contact PI
Sub 6 at Columbia$175,100
U54 · FY2006 · GM · contact PI
CORE--PROTEIN EXPRESSION$153,759
P30 · FY2006 · DK · contact PI
Crystal Structure for Desmoqlein 4$32,200
P30 · FY2006 · AR · contact PI
CADHERIN CELL ADHESION PROTEINS$2,661
P41 · FY2006 · RR · contact PI
SUBPROJECT 3$350,467
U54 · FY2005 · GM
Sub 6 at Columbia$170,000
U54 · FY2005 · GM
CORE--PROTEIN EXPRESSION$153,759
P30 · FY2005 · DK
BIOLOGY OF HYPOTHALMIC CONTROL OF ADIPOSITY AND STRUCTURAL GENOMICS$10,218
P41 · FY2005 · RR
MOLECULAR BASIS OF CADHERIN MEDIATED CELL ADHESION$245,250
R01 · FY2004 · GM
CORE--PROTEIN EXPRESSION$153,759
P30 · FY2004 · DK
HYPOTHALMIC CONTROL OF ADIPOSITY AND STRUCTURAL GENOMICS$23,969
P41 · FY2004 · RR
MOLECULAR BASIS OF CADHERIN MEDIATED CELL ADHESION$245,250
R01 · FY2003 · GM
CORE--PROTEIN EXPRESSION$228,759
P30 · FY2003 · DK
MOLECULAR BASIS OF CADHERIN MEDIATED CELL ADHESION$245,250
R01 · FY2002 · GM
MOLECULAR BASIS OF CADHERIN MEDIATED CELL ADHESION$204,990
R01 · FY2001 · GM
MOLECULAR BASIS OF CADHERIN MEDIATED CELL ADHESION$41,737
R01 · FY2001 · GM