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Jay D Humphrey

Yale University

$27,724,941
Attributed
$43,425,799
Total exposure
28
Grants
20
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $6M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$45,933,894 · 29

By mechanism

R01$31,782,209 · 13
P01$6,827,534 · 6
U01$5,155,306 · 2
R21$1,560,301 · 4
R03$608,544 · 4

Others in their field

Top investigators on “Biomechanics

Research focus

BiomechanicsMechanicsHemodynamicsPropertyBlood VesselsStructureMorbidity - Disease RateBiologicalAortaRuptureMouse ModelResponseCellsGrowthExtracellular MatrixBaseStressInsightMortalityDissectionIn VivoGeometryTissuesDilatation - Action

Grant awards (105)

Dynamic Cell-Matrix Interactions Dictate Thoracic Aortopathy$2,508,095
P01 · FY2025 · HL · contact PI
ELUCIDATING MECHANISMS OF THORACIC AORTOPATHY VIA COMPUTATIONAL MODELING$669,807
R01 · FY2025 · HL · contact PI
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$666,476
R01 · FY2025 · HL
Computational model-driven design to mitigate vein graft failure after coronary artery bypass$604,064
R01 · FY2025 · HL
Modeling Multiscale Immuno-Mechanics in Aortic Disease$491,820
R01 · FY2025 · HL · contact PI
Dynamic Cell-Matrix Interactions Dictate Thoracic Aortopathy$358,300
P01 · FY2025 · HL · contact PI
Dynamic Cell-Matrix Interactions Dictate Thoracic Aortopathy$358,300
P01 · FY2025 · HL · contact PI
Integrative Mechanobiological Understanding of Effects of Hypertension and Exercise on Thoracic Aortopathy$358,298
P01 · FY2025 · HL · contact PI
ELUCIDATING MECHANISMS OF THORACIC AORTOPATHY VIA COMPUTATIONAL MODELING$705,944
R01 · FY2024 · HL · contact PI
Computational model-driven design to mitigate vein graft failure after coronary artery bypass$679,261
R01 · FY2024 · HL
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$666,199
R01 · FY2024 · HL
Modeling Multiscale Immuno-Mechanics in Aortic Disease$488,551
R01 · FY2024 · HL · contact PI
Computational model-driven design to mitigate vein graft failure after coronary artery bypass$700,795
R01 · FY2023 · HL
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$692,237
R01 · FY2023 · HL
Modeling Multiscale Immuno-Mechanics in Aortic Disease$491,820
R01 · FY2023 · HL · contact PI
Computational model-driven design to mitigate vein graft failure after coronary artery bypass$752,426
R01 · FY2022 · HL
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$731,320
R01 · FY2022 · HL
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$652,823
R01 · FY2022 · HL
Multimodality imaging-driven multifidelity modeling of aortic dissection$559,400
U01 · FY2022 · HL · contact PI
Modeling Multiscale Immuno-Mechanics in Aortic Disease$500,195
R01 · FY2022 · HL · contact PI
TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells Govern Aneurysms$417,309
P01 · FY2022 · HL · contact PI
Core C: Computational and Experimental Biomechanical Assessment (CEBA)$222,205
P01 · FY2022 · HL · contact PI
Multiscale Modeling of Aortic Homeostasis$83,750
R03 · FY2022 · EB · contact PI
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$47,570
R01 · FY2022 · HL
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$882,339
R01 · FY2021 · HL
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$773,693
R01 · FY2021 · HL
Multimodality imaging-driven multifidelity modeling of aortic dissection$559,400
U01 · FY2021 · HL · contact PI
TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells Govern Aneurysms$419,653
P01 · FY2021 · HL · contact PI
Core C: Computational and Experimental Biomechanical Assessment (CEBA)$222,409
P01 · FY2021 · HL · contact PI
Multiscale Modeling of Aortic Homeostasis$83,750
R03 · FY2021 · EB · contact PI
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$928,842
R01 · FY2020 · HL
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$652,821
R01 · FY2020 · HL
Multimodality imaging-driven multifidelity modeling of aortic dissection$601,275
U01 · FY2020 · HL · contact PI
TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells Govern Aneurysms$421,894
P01 · FY2020 · HL · contact PI
Core C: Computational and Experimental Biomechanical Assessment (CEBA)$222,606
P01 · FY2020 · HL · contact PI
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$73,300
R01 · FY2020 · HL
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$964,560
R01 · FY2019 · HL
Smooth Muscle Cell Proliferation and Degradative Phenotype in Thoracic Aorta Aneurysm and Dissection$652,821
R01 · FY2019 · HL
Multimodality imaging-driven multifidelity modeling of aortic dissection$506,426
U01 · FY2019 · HL · contact PI
TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells Govern Aneurysms$423,514
P01 · FY2019 · HL · contact PI
Mechanisms Underlying The Progression of Large Artery Stiffness in Hypertension$354,728
R01 · FY2019 · HL
Core C: Computational and Experimental Biomechanical Assessment (CEBA)$222,749
P01 · FY2019 · HL · contact PI
Improving Tissue Engineered Vascular Graft Performance via Computational Modeling$917,170
R01 · FY2018 · HL
Multimodality imaging-driven multifidelity modeling of aortic dissection$528,639
U01 · FY2018 · HL · contact PI
Computational Model Driven Design of Tissue Engineered Vascular Grafts$497,884
R01 · FY2018 · HL · contact PI
TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells Govern Aneurysms$436,952
P01 · FY2018 · HL · contact PI
Mechanisms Underlying The Progression of Large Artery Stiffness in Hypertension$356,278
R01 · FY2018 · HL
Core C: Computational and Experimental Biomechanical Assessment (CEBA)$235,250
P01 · FY2018 · HL · contact PI
Characterization of TGFB-Dependent Mechanoresponses by Aortic Smooth Muscle Cells$599,426
R01 · FY2017 · HL
Computational Model Driven Design of Tissue Engineered Vascular Grafts$575,141
R01 · FY2017 · HL · contact PI
Multiscale, Multiphysics Model of Thrombus Biomechanics in Aortic Dissection$455,081
U01 · FY2017 · HL · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$387,115
R01 · FY2017 · HL · contact PI
Mechanisms Underlying The Progression of Large Artery Stiffness in Hypertension$354,728
R01 · FY2017 · HL
A new paradigm for aortic dissection: Mechanical mechanisms of delamination$251,250
R21 · FY2017 · EB · contact PI
Genetically-altered mechanical homeostasis in central arteries$72,202
R03 · FY2017 · EB · contact PI
Multiscale, Multiphysics Model of Thrombus Biomechanics in Aortic Dissection$503,285
U01 · FY2016 · HL · contact PI
Computational Model Driven Design of Tissue Engineered Vascular Grafts$494,739
R01 · FY2016 · HL · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$388,370
R01 · FY2016 · HL · contact PI
Mechanisms Underlying The Progression of Large Artery Stiffness in Hypertension$375,028
R01 · FY2016 · HL
A new paradigm for aortic dissection: Mechanical mechanisms of delamination$209,375
R21 · FY2016 · EB · contact PI
Computational Model Driven Design of Tissue Engineered Vascular Grafts$84,989
R01 · FY2016 · HL · contact PI
Genetically-altered mechanical homeostasis in central arteries$72,559
R03 · FY2016 · EB · contact PI
Computational Model Driven Design of Tissue Engineered Vascular Grafts$532,529
R01 · FY2015 · HL · contact PI
Multiscale, Multiphysics Model of Thrombus Biomechanics in Aortic Dissection$474,118
U01 · FY2015 · HL · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$383,726
R01 · FY2015 · HL · contact PI
Multiscale, Multiphysics Model of Thrombus Biomechanics in Aortic Dissection$489,719
U01 · FY2014 · HL · contact PI
Mechanisms Underlying the Progression of Arterial Stiffness in Hypertension$386,146
R01 · FY2014 · HL · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$382,905
R01 · FY2014 · HL · contact PI
Computational Modeling and Accelerated Aging of the Ascending Aorta$71,198
R03 · FY2014 · EB · contact PI
Multiscale, Multiphysics Model of Thrombus Biomechanics in Aortic Dissection$477,963
U01 · FY2013 · HL · contact PI
Mechanisms Underlying the Progression of Arterial Stiffness in Hypertension$371,686
R01 · FY2013 · HL · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$347,650
R01 · FY2013 · HL · contact PI
Gender Specific Evolution of Abdominal Aortic Aneurysm Composition and Properties$225,431
R21 · FY2013 · HL · contact PI
Computational Modeling and Accelerated Aging of the Ascending Aorta$74,088
R03 · FY2013 · EB · contact PI
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$486,322
R01 · FY2012 · HL · contact PI
Gender Specific Evolution of Abdominal Aortic Aneurysm Composition and Properties$195,298
R21 · FY2012 · HL · contact PI
Mechanisms Underlying the Progression of Arterial Stiffness in Hypertension$392,805
R01 · FY2011 · HL · contact PI
Enabling Strategies for Growing Collagenous Tissues$507,297
R01 · FY2010 · EB
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$454,190
R01 · FY2010 · HL · contact PI
Mechanisms Underlying the Progression of Arterial Stiffness in Hypertension$406,197
R01 · FY2010 · HL · contact PI
EVOLVING MECHANICS OF INTRALUMINAL THROMBUS: FROM FORMATION TO ORGANIZATION$81,923
R03 · FY2010 · EB · contact PI
Enabling Strategies for Growing Collagenous Tissues$498,486
R01 · FY2009 · EB
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$458,579
R01 · FY2009 · HL · contact PI
Enabling Strategies for Growing Collagenous Tissues$177,242
R01 · FY2009 · EB
Constrictor / Mitogen Induced Remodeling of Cerebral Arterioles$151,805
R21 · FY2009 · NS · contact PI
EVOLVING MECHANICS OF INTRALUMINAL THROMBUS: FROM FORMATION TO ORGANIZATION$69,074
R03 · FY2009 · EB · contact PI
Constrictor / Mitogen Induced Remodeling of Cerebral Arterioles$1,000
R21 · FY2009 · NS · contact PI
Enabling Strategies for Growing Collagenous Tissues$484,958
R01 · FY2008 · EB
Biomechanical Simulation of Evolving Aortic Aneurysms for Designing Intervention$476,605
R01 · FY2008 · HL · contact PI
Ex Vivo Delineation of Mechanisms of Cerebral Vasospasm$286,825
R01 · FY2008 · HL · contact PI
Constrictor / Mitogen Induced Remodeling of Cerebral Arterioles$185,206
R21 · FY2008 · NS · contact PI
Enabling Strategies for Growing Collagenous Tissues$531,128
R01 · FY2007 · EB
Ex Vivo Delineation of Mechanisms of Cerebral Vasospasm$286,825
R01 · FY2007 · HL · contact PI
Ex Vivo Delineation of Mechanisms of Cerebral Vasospasm$295,392
R01 · FY2006 · HL · contact PI
Histo-Mechanics &Biology of Remodeling in Hypertension$653,288
R01 · FY2005 · HL
Ex Vivo Delineation of Mechanisms of Cerebral Vasospasm$327,500
R01 · FY2005 · HL
Novel Organ Culture &Theory for Arteriolar Remodeling$155,693
R21 · FY2005 · HL
Histo-Mechanics &Biology of Remodeling in Hypertension$639,178
R01 · FY2004 · HL
Novel Organ Culture &Theory for Arteriolar Remodeling$185,243
R21 · FY2004 · HL
Histo-Mechanics &Biology of Remodeling in Hypertension$636,520
R01 · FY2003 · HL
Mechanical Stress and the Heat-Treatment of Soft Tissue$136,485
R01 · FY2003 · HL
Histo-Mechanics &Biology of Remodeling in Hypertension$563,572
R01 · FY2002 · HL
Mechanical Stress and the Heat-Treatment of Soft Tissue$135,672
R01 · FY2002 · HL
Histo-Mechanics &Biology of Remodeling in Hypertension$552,337
R01 · FY2001 · HL
Mechanical Stress and the Heat-Treatment of Soft Tissue$134,884
R01 · FY2001 · HL