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Mark Thomas Gladwin

Clinical Center

$38,765,597
Attributed
$51,971,784
Total exposure
14
Grants
14
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $6.9M · FY200925
$10M$7.5M$5M$2.5M$0
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$75,323,142 · 15

By mechanism

P01$29,966,552 · 5
R01$21,168,928 · 4
UH3$16,082,959 · 1
T32$4,192,321 · 2
UG3$1,459,550 · 1
P30$1,453,652 · 1

Top collaborators

Most similar at Clinical Center

Same institution · by research overlap

Others in their field

Top investigators on “Nitric Oxide

Research focus

Nitric OxideBlood VesselsLungHemoglobinErythrocytesSickle Cell AnemiaIn VivoSignal TransductionNitritesCellsBaseClinical TrialsBloodSafetyPathway InteractionsPhysiologicalIn VitroFunctional DisorderHemolysisProgramsReactionAcuteMouse ModelProtocols Documentation

Grant awards (145)

Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRE$1,171,075
UH3 · FY2025 · HL · contact PI
Omics, mice and men: Development of precision transfusion medicine$765,351
R01 · FY2025 · HL · contact PI
Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversus$697,617
R01 · FY2025 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$676,342
R01 · FY2025 · HL · contact PI
Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRE$2,550,443
UH3 · FY2024 · HL · contact PI
Omics, mice and men: Development of precision transfusion medicine$750,647
R01 · FY2024 · HL · contact PI
Airway epithelial cytoglobin regulates nitric oxide synthase and development of primary ciliary dyskinesia and situs inversus$724,867
R01 · FY2024 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$660,807
R01 · FY2024 · HL · contact PI
Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRE$3,349,999
UH3 · FY2023 · HL · contact PI
Omics, mice and men: Development of precision transfusion medicine$825,222
R01 · FY2023 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$703,592
R01 · FY2023 · HL · contact PI
Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRE$2,667,908
UH3 · FY2022 · HL · contact PI
1/2 Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE Trial)$680,622
UH3 · FY2022 · HL · contact PI
1/2 Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE Trial)$2,887,088
UH3 · FY2021 · HL · contact PI
Omics, mice, and men: Development of precision transfusion medicine$758,633
R01 · FY2021 · HL
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$708,733
R01 · FY2021 · HL · contact PI
Training in Translational Research and Entrepreneurship in Pulmonary Vascular Biology$207,136
T32 · FY2021 · HL · contact PI
1/2 Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE Trial)$2,775,824
UH3 · FY2020 · HL · contact PI
Omics, mice, and men: Development of precision transfusion medicine$759,318
R01 · FY2020 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$708,733
R01 · FY2020 · HL · contact PI
Nitrite-signaling to modulate the metabolic syndrome and PH in patients with PH-HFpEF$630,438
P01 · FY2020 · HL · contact PI
Training in Translational Research and Entrepreneurship in Pulmonary Vascular Biology$550,298
T32 · FY2020 · HL · contact PI
Administrative Core$156,501
P01 · FY2020 · HL · contact PI
Therapeutic Targeting of Vascular Subphenotypes of Lung Disease$2,713,014
P01 · FY2019 · HL · contact PI
1/2 Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE Trial)$1,459,550
UG3 · FY2019 · HL · contact PI
Omics, mice, and men: Development of precision transfusion medicine$759,990
R01 · FY2019 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$722,858
R01 · FY2019 · HL · contact PI
Nitrite-signaling to modulate the metabolic syndrome and PH in patients with PH-HFpEF$630,438
P01 · FY2019 · HL · contact PI
Training in Translational Research and Entrepreneurship in Pulmonary Vascular Biology$420,322
T32 · FY2019 · HL · contact PI
Administrative Core$156,500
P01 · FY2019 · HL · contact PI
Therapeutic Targeting of Vascular Subphenotypes of Lung Disease$2,714,385
P01 · FY2018 · HL · contact PI
Omics, mice, and men: Development of precision transfusion medicine$788,194
R01 · FY2018 · HL · contact PI
Nitrite-signaling to modulate the metabolic syndrome and PH in patients with PH-HFpEF$630,438
P01 · FY2018 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$574,328
R01 · FY2018 · HL · contact PI
Training in Translational Research and Entrepreneurship in Pulmonary Vascular Biology$334,656
T32 · FY2018 · HL · contact PI
Administrative Core$156,501
P01 · FY2018 · HL · contact PI
Therapeutic Targeting of Vascular Subphenotypes of Lung Disease$2,700,395
P01 · FY2017 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$651,399
R01 · FY2017 · HL · contact PI
Nitrite-signaling to modulate the metabolic syndrome and PH in patients with PH-HFpEF$626,746
P01 · FY2017 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$582,028
R01 · FY2017 · HL · contact PI
Training in Translational Research and Entrepreneurship in Pulmonary Vascular Biology$335,915
T32 · FY2017 · HL · contact PI
Administrative Core$155,584
P01 · FY2017 · HL · contact PI
Translational Pulmonary Vascular Biology$1,944
T32 · FY2017 · HL · contact PI
Therapeutic Targeting of Vascular Subphenotypes of Lung Disease$2,704,375
P01 · FY2016 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$645,717
R01 · FY2016 · HL · contact PI
Nitrite-signaling to modulate the metabolic syndrome and PH in patients with PH-HFpEF$620,871
P01 · FY2016 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$595,927
R01 · FY2016 · HL · contact PI
Administrative Core$154,125
P01 · FY2016 · HL · contact PI
Translational Pulmonary Vascular Biology$125,670
T32 · FY2016 · HL · contact PI
Vascular Subphenotypes of Lung Disease$2,459,371
P01 · FY2015 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$746,695
R01 · FY2015 · HL · contact PI
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin$613,799
R01 · FY2015 · HL · contact PI
Pulmonary vascular-targeted NO therapeutic strategies$447,710
P01 · FY2015 · HL · contact PI
Translational Pulmonary Vascular Biology$188,684
T32 · FY2015 · HL · contact PI
Administrative Core$97,905
P01 · FY2015 · HL · contact PI
Vascular Subphenotypes of Lung Disease$2,477,787
P01 · FY2014 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$684,147
R01 · FY2014 · HL · contact PI
Translational Training Program in Pulmonary Biology and Medicine$654,104
T32 · FY2014 · HL · contact PI
Pulmonary vascular-targeted NO therapeutic strategies$446,099
P01 · FY2014 · HL · contact PI
Translational Pulmonary Vascular Biology$309,083
T32 · FY2014 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$100,000
R01 · FY2014 · HL · contact PI
Administrative Core$90,968
P01 · FY2014 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$49,621
R01 · FY2014 · HL · contact PI
Vascular Subphenotypes of Lung Disease$2,437,938
P01 · FY2013 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$670,537
R01 · FY2013 · HL · contact PI
Translational Training Program in Pulmonary Biology and Medicine$612,011
T32 · FY2013 · HL · contact PI
Pulmonary vascular-targeted NO therapeutic strategies$432,711
P01 · FY2013 · HL · contact PI
Myoglobin as a Nitrite Reductase that Regulates Hypoxic Cardiac NO Signaling$345,471
R01 · FY2013 · HL · contact PI
Translational Pulmonary Vascular Biology$303,212
T32 · FY2013 · HL · contact PI
Administrative Core$94,624
P01 · FY2013 · HL · contact PI
Vascular Subphenotypes of Lung Disease$2,556,023
P01 · FY2012 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$672,697
R01 · FY2012 · HL · contact PI
Pulmonary vascular-targeted NO therapeutic strategies$438,774
P01 · FY2012 · HL · contact PI
Myoglobin as a Nitrite Reductase that Regulates Hypoxic Cardiac NO Signaling$363,051
R01 · FY2012 · HL · contact PI
Translational Pulmonary Vascular Biology$149,286
T32 · FY2012 · HL · contact PI
Administrative Core$99,396
P01 · FY2012 · HL · contact PI
Vascular Subphenotypes of Lung Disease$2,588,070
P01 · FY2011 · HL · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$688,267
R01 · FY2011 · HL · contact PI
Pulmonary vascular-targeted NO therapeutic strategies$440,379
P01 · FY2011 · HL · contact PI
Myoglobin as a Nitrite Reductase that Regulates Hypoxic Cardiac NO Signaling$367,978
R01 · FY2011 · HL · contact PI
Administrative Core$108,486
P01 · FY2011 · HL · contact PI
Translational Vascular Biology in Autoimmune Diseases$744,615
P30 · FY2010 · AR · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$695,694
R01 · FY2010 · HL · contact PI
Dietary nitrate activation of PPARgamma improves insulin sensitivity$499,591
RC1 · FY2010 · DK · contact PI
Myoglobin as a Nitrite Reductase that Regulates Hypoxic Cardiac NO Signaling$404,561
R01 · FY2010 · HL · contact PI
Translational Vascular Biology in Autoimmune Diseases$709,037
P30 · FY2009 · AR · contact PI
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide Homeostasis$706,107
R01 · FY2009 · HL · contact PI
Dietary nitrate activation of PPARgamma improves insulin sensitivity$499,589
RC1 · FY2009 · DK · contact PI
Multicenter Trial of NO for Acute Treatment of Sickle Cell Pain Episodes$1,228,440
Z01 · FY2008 · HL · contact PI
Prevalence of PAH in SCD Patients in Nigeria$954,218
Z01 · FY2008 · HL · contact PI
Hemolysis, NO and PAH in Malaria$954,218
Z01 · FY2008 · HL · contact PI
Synergy of Hydroxyurea and Erythropoietin on Fetal Hemoglobin in SCD$635,991
Z01 · FY2008 · HL · contact PI
Prevalence And Prognosis Of Pulmonary Hypertension In Adults With Sickle Cell$87,018
Z01 · FY2008 · CL · contact PI
Blood Studies of Endothelial Function and Systemic Inflammation$32,321
Z01 · FY2008 · CL · contact PI
Systemic Nitrite Infusion and its Effect on Exercise Physiology and Metabolism$31,962
Z01 · FY2008 · HL · contact PI
Nitrite Infusion Studies on Healthy Volunteers$31,962
Z01 · FY2008 · HL · contact PI
Use of Hydroxyurea & L-arginine or Sildenafil in Patients w/Sickle Cell Disease$31,962
Z01 · FY2008 · HL · contact PI
Nitric Oxide For Patients With Sickle Cell Anemia And Pulmonary Hypertension$4,972
Z01 · FY2008 · CL · contact PI
Multicenter Trial of NO for Acute Treatment of Sickle Cell Pain Episodes$821,996
Z01 · FY2007 · HL · contact PI
Synergy of Hydroxyurea and Erythropoietin on Fetal Hemoglobin in SCD$748,968
Z01 · FY2007 · HL · contact PI
Prevalence of PAH in SCD Patients in Nigeria$641,972
Z01 · FY2007 · HL · contact PI
Hemolysis, NO and PAH in Malaria$641,972
Z01 · FY2007 · HL · contact PI
Nitrite Infusion Studies on Healthy Volunteers$213,991
Z01 · FY2007 · HL · contact PI
Systemic Nitrite Infusion and its Effect on Exercise Physiology and Metabolism$213,991
Z01 · FY2007 · HL · contact PI
Use of Hydroxyurea & L-arginine or Sildenafil in Patients w/Sickle Cell Disease$213,991
Z01 · FY2007 · HL · contact PI
Use of Bosentan in Patients with Symptomatic PH Associated with SCD$213,991
Z01 · FY2007 · HL · contact PI
Prevalence And Prognosis Of Pulmonary Hypertension In Adults With Sickle Cell$43,600
Z01 · FY2007 · CL · contact PI
Blood Studies of Endothelial Function and Systemic Inflammation$16,764
Z01 · FY2007 · CL · contact PI
Cardiopulmonary Function Assessment and NO Based Therapies for SCD Pts with PAH$16,612
Z01 · FY2007 · CL · contact PI
Evaluation of Endothelial Function in HIV Associated PAH$10,900
Z01 · FY2007 · CL · contact PI
Nitric Oxide For Patients With Sickle Cell Anemia And Pu$0
Z01 · FY2006 · CL · contact PI
Use of Hydroxyurea & L-arginine or Sildenafil in Patient$0
Z01 · FY2006 · HL · contact PI
Synergy of Hydroxyurea and Erythropoietin on Fetal Hemog$0
Z01 · FY2006 · HL · contact PI
Prevalence of PAH in SCD Patients in Nigeria$0
Z01 · FY2006 · HL · contact PI
Nitrite Infusion Studies on Healthy Volunteers$0
Z01 · FY2006 · HL · contact PI
Multicenter Trial of NO for Acute Treatment of Sickle Ce$0
Z01 · FY2006 · HL · contact PI
Systemic Nitrite Infusion and its Effect on Exercise Phy$0
Z01 · FY2006 · HL · contact PI
Blood Studies of Endothelial Function and Systemic Infla$0
Z01 · FY2006 · CL · contact PI
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2006 · CL · contact PI
Nitric Oxide For Patients With Sickle Cell Anemia And Pu$0
Z01 · FY2005 · CL
Nitrite Infusion Studies on Healthy Volunteers$0
Z01 · FY2005 · HL
Systemic Nitrite Infusion and its Effect on Exercise Phy$0
Z01 · FY2005 · HL
Multicenter Trial of NO for Acute Treatment of Sickle Ce$0
Z01 · FY2005 · HL
Use of Hydroxyurea &L-arginine or Sildenafil in SCD$0
Z01 · FY2005 · CL
Blood Studies of Endothelial Function and Systemic Infla$0
Z01 · FY2005 · CL
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2005 · CL
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2005 · CL
Nitric Oxide: Sickle Cell Anemia/Pulmonary Hypertension$0
Z01 · FY2004 · CL
Hydroxyurea/L-arginine or Sildenafil Sickle Cell Disease$0
Z01 · FY2004 · CL
Blood Studies Endothelial Function/Systemic Inflammation$0
Z01 · FY2004 · CL
Sickle Cell: Risk/Prognosis Of Pulmonary Hypertension$0
Z01 · FY2004 · CL
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2003 · CL
Hydroxyurea &L-arginine or Sildenafil in Patients w/SCD$0
Z01 · FY2003 · CL
Blood Studies of Endothelial Function /Systemic Inflamma$0
Z01 · FY2003 · CL
Nitric Oxide For Patients With Sickle Cell Anemia And Pu$0
Z01 · FY2003 · CL
Nitric Oxide For Patients With Sickle Cell Anemia And Pu$0
Z01 · FY2002 · CL
Delivery Of NO By Hemoglobin To Improve Blood Flow In Si$0
Z01 · FY2002 · CL
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2002 · CL
Physiologic Effects Of Inhaled Nitric Oxide, Nitroglycer$0
Z01 · FY2002 · CL
Physiologic Effects Of Inhaled Nitric Oxide, Nitroglycer$0
Z01 · FY2001 · CL
Effects Of Endothelium-derived Versus Hemoglobin-transpo$0
Z01 · FY2001 · CL
Delivery Of NO By Hemoglobin To Improve Blood Flow In Si$0
Z01 · FY2001 · CL
Prevalence And Prognosis Of Pulmonary Hypertension In Ad$0
Z01 · FY2001 · CL
Nitric Oxide For Patients With Sickle Cell Anemia And Pu$0
Z01 · FY2001 · CL
Physiologic Effects of Inhaled Nitric Oxide, Nitroglycerin, and Placebo in Study$0
Z01 · FY2000 · CL