← Leaderboards
Leonard Petrucelli
Mayo Clinic Jacksonville
$43,938,031
Attributed
$55,921,308
Total exposure
31
Grants
25
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $13.9M · FY2006–25$20M$15M$10M$5M$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$94,389,911 · 35
By mechanism
P01$33,490,212 · 9
U54$18,863,158 · 6
R35$11,720,237 · 2
R01$9,562,037 · 6
U01$9,304,126 · 2
RF1$7,853,730 · 2
Top collaborators
- Aaron D. Gitler8 shared
- Jeffrey D Rothstein7 shared
- Matthew D Disney6 shared
- Mercedes Prudencio6 shared
- Towfique Raj6 shared
- William W Seeley6 shared
- Anthony William Paul Fitzpatrick5 shared
- Pietro Fratta5 shared
Most similar at Mayo Clinic Jacksonville
Same institution · by research overlap
- Kevin Boylan$2,850,878
- Tania France Gendron$4,632,093
- Bjorn E Oskarsson$14,441,633
- Casey N Cook$5,433,329
- Jordan David Marks$98,912
Others in their field
Top investigators on “Nerve Degeneration”
- Paul S. Aisen · Cognition Therapeutics, Inc.$113,855,136
- Reisa A. Sperling · Banner Health$83,196,776
- Randall J Bateman · Washington University$83,099,227
- Sterling C Johnson · St. Joseph'S Hospital And Medical Center$76,236,227
- Jose A Luchsinger · Columbia University Health Sciences$75,117,371
- Keith A. Johnson · Banner Health$70,466,464
Research focus
Nerve DegenerationProteinsGeneticBrainNeuronsPathologyMouse ModelMutationCellsToxic EffectBiological MarkersFrontotemporal DementiaNeurodegenerative DisordersPathogenesisC9orf72LinkPathologicTau ProteinsAmyotrophic Lateral SclerosisInsightClinicGenesIn VivoResearch Personnel
Grant awards (138)
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$1,572,782
U54 · FY2025 · NS
Expanding insights into FTD disease mechanisms$1,138,538
R35 · FY2025 · NS · contact PI
Investigating the role of TMEM106b genetics and pathology in Alzheimerâs disease, LATE and FTLD$1,060,236
R01 · FY2025 · NS · contact PI
Human Biomarkers Core$353,968
U54 · FY2025 · NS · contact PI
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$53,900
U54 · FY2025 · NS
Pathobiology of Neurodegeneration in C9ORF72 repeat expansion$2,581,235
P01 · FY2024 · NS · contact PI
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$1,598,861
U54 · FY2024 · NS
Investigating the role of TMEM106b genetics and pathology in Alzheimerâs disease, LATE and FTLD$1,064,348
R01 · FY2024 · NS · contact PI
Expanding insights into FTD disease mechanisms$985,949
R35 · FY2024 · NS · contact PI
Project 2$450,312
P01 · FY2024 · NS · contact PI
Project 3$425,116
P01 · FY2024 · NS · contact PI
Biomarker Core$357,585
P30 · FY2024 · AG · contact PI
Human Biomarkers Core$353,786
U54 · FY2024 · NS · contact PI
Admin Core$350,826
P01 · FY2024 · NS · contact PI
Core D$231,749
P01 · FY2024 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 repeat expansion$2,328,355
P01 · FY2023 · NS · contact PI
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$1,597,452
U54 · FY2023 · NS
Investigating the role of TMEM106b genetics and pathology in Alzheimerâs disease, LATE and FTLD$1,097,060
R01 · FY2023 · NS · contact PI
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2023 · NS · contact PI
Project 2$450,313
P01 · FY2023 · NS · contact PI
Project 3$432,289
P01 · FY2023 · NS · contact PI
Human Biomarkers Core$352,160
U54 · FY2023 · NS · contact PI
Biomarker Core$310,119
P30 · FY2023 · AG · contact PI
Core D$231,750
P01 · FY2023 · NS · contact PI
Admin Core$72,100
P01 · FY2023 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 repeat expansion$2,108,893
P01 · FY2022 · NS · contact PI
Expanding insights into FTD disease mechanisms$2,059,125
R35 · FY2022 · NS · contact PI
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$1,644,973
U54 · FY2022 · NS
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry$1,629,162
U01 · FY2022 · NS
Project 2$416,838
P01 · FY2022 · NS · contact PI
Project 3$416,660
P01 · FY2022 · NS · contact PI
Human Biomarkers Core$355,175
U54 · FY2022 · NS · contact PI
Biomarker Core$286,007
P30 · FY2022 · AG · contact PI
Core D$198,275
P01 · FY2022 · NS · contact PI
Admin Core$31,303
P01 · FY2022 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 repeat expansion$2,357,659
P01 · FY2021 · NS · contact PI
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets$1,722,003
U54 · FY2021 · NS
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry$1,629,162
U01 · FY2021 · NS
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2021 · NS · contact PI
Expanding insights into FTD disease mechanisms$963,625
R35 · FY2021 · NS · contact PI
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$677,625
P01 · FY2021 · NS
Project 3$456,489
P01 · FY2021 · NS · contact PI
Project 2$450,313
P01 · FY2021 · NS · contact PI
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$413,819
P01 · FY2021 · NS
Human Biomarkers Core$370,118
U54 · FY2021 · NS · contact PI
Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development$259,424
P01 · FY2021 · NS · contact PI
Core D$231,750
P01 · FY2021 · NS · contact PI
Admin Core$68,652
P01 · FY2021 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 repeat expansion$2,442,288
P01 · FY2020 · NS · contact PI
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry$1,629,162
U01 · FY2020 · NS
Identifying genes and Pathways that impact Tau Toxicity in FTD$1,216,084
U54 · FY2020 · NS · contact PI
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2020 · NS · contact PI
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$1,091,444
P01 · FY2020 · NS
Project 2: Identifying genes and Pathways that impact Tau Toxicity in FTD$507,824
U54 · FY2020 · NS · contact PI
Project 3$476,717
P01 · FY2020 · NS · contact PI
Project 2$464,438
P01 · FY2020 · NS · contact PI
Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development$259,424
P01 · FY2020 · NS · contact PI
Core D$245,875
P01 · FY2020 · NS · contact PI
Admin Core$72,461
P01 · FY2020 · NS · contact PI
Admin Core: Identifying genes and Pathways that impact Tau Toxicity in FTD$35,213
U54 · FY2020 · NS · contact PI
Novel genetic modifiers of C9orf72 and Tau toxicity$4,037,235
RF1 · FY2019 · AG
Nuclear Pore Complex and as a Contributor to Tau Associated Dementia$3,816,495
RF1 · FY2019 · AG
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$1,435,400
P01 · FY2019 · NS
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry$1,434,762
U01 · FY2019 · NS
Identifying genes and Pathways that impact Tau Toxicity in FTD$1,216,084
U54 · FY2019 · NS · contact PI
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2019 · NS · contact PI
Project 2: Identifying genes and Pathways that impact Tau Toxicity in FTD$507,824
U54 · FY2019 · NS · contact PI
Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development$348,955
P01 · FY2019 · NS · contact PI
Admin Core: Identifying genes and Pathways that impact Tau Toxicity in FTD$35,213
U54 · FY2019 · NS · contact PI
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry$1,465,762
U01 · FY2018 · NS
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$1,435,400
P01 · FY2018 · NS
Identifying genes and Pathways that impact Tau Toxicity in FTD$1,216,084
U54 · FY2018 · NS · contact PI
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2018 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$986,853
P01 · FY2018 · NS · contact PI
Project 2: Identifying genes and Pathways that impact Tau Toxicity in FTD$507,824
U54 · FY2018 · NS · contact PI
Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development$348,955
P01 · FY2018 · NS · contact PI
The role of acetylation in regulating pathophysiology of tau$263,422
R01 · FY2018 · NS · contact PI
Administrative Core$243,227
P01 · FY2018 · NS · contact PI
Project 2$235,243
P50 · FY2018 · AG · contact PI
Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS$48,645
P01 · FY2018 · NS · contact PI
Admin Core: Identifying genes and Pathways that impact Tau Toxicity in FTD$35,213
U54 · FY2018 · NS · contact PI
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways$1,481,400
P01 · FY2017 · NS
Identifying genes and Pathways that impact Tau Toxicity in FTD$1,216,084
U54 · FY2017 · NS · contact PI
Expanding insights into FTD disease mechanisms$1,095,500
R35 · FY2017 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$986,853
P01 · FY2017 · NS · contact PI
Project 2: Identifying genes and Pathways that impact Tau Toxicity in FTD$507,824
U54 · FY2017 · NS · contact PI
Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development$296,280
P01 · FY2017 · NS · contact PI
The role of acetylation in regulating pathophysiology of tau$263,422
R01 · FY2017 · NS · contact PI
Administrative Core$243,227
P01 · FY2017 · NS · contact PI
Project 2$242,519
P50 · FY2017 · AG · contact PI
Identifying genes and Pathways that impact Tau Toxicity in FTD$50,000
U54 · FY2017 · NS · contact PI
Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS$48,645
P01 · FY2017 · NS · contact PI
Admin Core: Identifying genes and Pathways that impact Tau Toxicity in FTD$35,213
U54 · FY2017 · NS · contact PI
Identifying genes and Pathways that impact Tau Toxicity in FTD$1,244,334
U54 · FY2016 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$1,102,845
P01 · FY2016 · NS · contact PI
Project 2: Identifying genes and Pathways that impact Tau Toxicity in FTD$521,949
U54 · FY2016 · NS · contact PI
The role of acetylation in regulating pathophysiology of tau$329,278
R01 · FY2016 · NS · contact PI
Administrative Core$291,398
P01 · FY2016 · NS · contact PI
Project 2$200,320
P50 · FY2016 · AG · contact PI
Defining the mechanisms of dipeptide repeat protein toxicity in C9orf72 ALS/FTD$140,241
R01 · FY2016 · NS
Admin Core: Identifying genes and Pathways that impact Tau Toxicity in FTD$35,213
U54 · FY2016 · NS · contact PI
Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS$33,174
P01 · FY2016 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$1,291,133
P01 · FY2015 · NS · contact PI
The role of acetylation in regulating pathophysiology of tau$526,845
R01 · FY2015 · NS · contact PI
Defining the mechanisms of dipeptide repeat protein toxicity in C9orf72 ALS/FTD$442,988
R01 · FY2015 · NS
Misregulation of the TDP-43 RNA target, Sortilin, in neurodegeneration$339,063
R01 · FY2015 · NS · contact PI
Administrative Core$322,780
P01 · FY2015 · NS · contact PI
Project 2$192,442
P50 · FY2015 · AG · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$107,627
P01 · FY2015 · NS · contact PI
Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS$64,555
P01 · FY2015 · NS · contact PI
Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion$1,291,133
P01 · FY2014 · NS · contact PI
The role of acetylation in regulating pathophysiology of tau$540,970
R01 · FY2014 · NS · contact PI
Misregulation of the TDP-43 RNA target, Sortilin, in neurodegeneration$335,673
R01 · FY2014 · NS · contact PI
Administrative Core$322,780
P01 · FY2014 · NS · contact PI
Progranulin, TDP-43 and Cell Death$301,480
R01 · FY2014 · AG · contact PI
Project 2$200,320
P50 · FY2014 · AG · contact PI
RNA foci in C9FTD/ALS$195,625
R21 · FY2014 · NS · contact PI
Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS$64,555
P01 · FY2014 · NS · contact PI
Misregulation of the TDP-43 RNA target, Sortilin, in neurodegeneration$327,196
R01 · FY2013 · NS · contact PI
Progranulin, TDP-43 and Cell Death$284,898
R01 · FY2013 · AG · contact PI
RNA foci in C9FTD/ALS$234,750
R21 · FY2013 · NS · contact PI
Development and Testing of Hsp90 Inhibitors$769,259
U01 · FY2012 · NS · contact PI
Misregulation of the TDP-43 RNA target, Sortilin, in neurodegeneration$339,063
R01 · FY2012 · NS · contact PI
Progranulin, TDP-43 and Cell Death$301,480
R01 · FY2012 · AG · contact PI
Misregulation of the TDP-43 RNA target, Sortilin, in neurodegeneration$339,063
R01 · FY2011 · NS · contact PI
Progranulin, TDP-43 and Cell Death$301,480
R01 · FY2011 · AG · contact PI
Development and Testing of Hsp90 Inhibitors$746,857
U01 · FY2010 · NS · contact PI
Progranulin, TDP-43 and Cell Death$313,650
R01 · FY2010 · AG · contact PI
Progranulin, TAR DNA binding protein-43 and Cell Death$382,500
R56 · FY2009 · AG · contact PI
Preclinical Evaluation of a Novel Hsp90 inhibitor in Mutant Tau Mice$200,813
R21 · FY2009 · NS · contact PI
Preclinical Evaluation of a Novel Hsp90 inhibitor in Mutant Tau Mice$167,344
R21 · FY2008 · NS · contact PI
CHIP: A Link between Parkin and Cell Death$199,249
R21 · FY2007 · NS · contact PI
The genetics of chromosome 17q21-linked tau-negative FTD$188,181
R01 · FY2007 · AG · contact PI
CHIP: A Link between Parkin and Cell Death$171,000
R21 · FY2006 · NS · contact PI
Parkin, Ubiquitination and Cell Death$154,000
R01 · FY2003 · NS
Parkin, Ubiquitination and Cell Death$154,000
R01 · FY2002 · NS
Parkin, Ubiquitination and Cell Death$154,000
R01 · FY2001 · NS
BETA AMYLOID EFFECTS ON NEUROTROPHIC RECEPTORS$20,575
F31 · FY2000 · MH