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Melanie A Ruffner
Children'S Hosp Of Philadelphia
$4,430,757
Attributed
$4,430,757
Total exposure
3
Grants
3
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).
Funding over time
peak $3.4M · FY2008–25$5M$3.8M$2.5M$1.3M$0
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$4,430,757 · 3
By mechanism
R01$3,375,359 · 1
K08$926,640 · 1
F30$128,758 · 1
Top collaborators
No co-investigators on record.
Most similar at Children'S Hosp Of Philadelphia
Same institution · by research overlap
- Amanda Brooke Muir$4,831,309
- Scott Matthew Lieberman$4,617,052
- Robert B Lindell$179,475
Others in their field
Top investigators on “Mediating”
- Bambra Strokes · Ppd Development Lp$526,656,217
- Lawrence Corey · Fred Hutchinson Cancer Center$493,822,581
- Barton F Haynes · Duke University$295,802,493
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$286,700,869
- Margaret Juliana McElrath · Fred Hutchinson Cancer Center$176,977,598
- Dan H. Barouch · Fred Hutchinson Cancer Center$122,734,499
Research focus
MediatingInterleukin-4CellsSignal TransductionInflammationCell PhysiologyPathogenesisPhenotypePlayModificationInflammatoryAutomobile DrivingHistologicBasal Cell HyperplasiaImpairmentInsightFunctional DisorderEsophagusAffectExposure ToChip-SeqFoundationsGene ExpressionEosinophilic Esophagitis
Grant awards (9)
Defining the impact of type 1 cytokine signaling on STAT-mediated epithelial reprogramming and barrier dysfunction in eosinophilic esophagitis$3,375,359
R01 · FY2025 · AI · contact PI
Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis$185,328
K08 · FY2024 · AI · contact PI
Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis$185,328
K08 · FY2023 · AI · contact PI
Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis$185,328
K08 · FY2022 · AI · contact PI
Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis$185,328
K08 · FY2021 · AI · contact PI
Epigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitis$185,328
K08 · FY2020 · AI · contact PI
IL-4 Overexpressing Dendritic Cells and Exosomes for Treatment of Type 1 Diabetes$41,085
F30 · FY2010 · DK · contact PI
IL-4 Overexpressing Dendritic Cells and Exosomes for Treatment of Type 1 Diabetes$46,176
F30 · FY2009 · DK · contact PI
IL-4 Overexpressing Dendritic Cells and Exosomes for Treatment of Type 1 Diabetes$41,497
F30 · FY2008 · DK · contact PI