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H Leighton Grimes

Cincinnati Childrens Hosp Med Ctr

$23,205,568
Attributed
$27,502,646
Total exposure
15
Grants
14
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.5M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$27,502,646 · 15

By mechanism

R01$20,219,663 · 9
RC2$5,265,236 · 1
R21$2,017,747 · 5

Others in their field

Top investigators on “Cells

Research focus

CellsMolecularGenesGeneticTranscription FactorBiologicalMouse ModelGenomicsIn VivoMediatingHematopoietic Stem CellsGenetic TranscriptionHematopoieticProductionProgramsMutationMyelogenousGene ExpressionData SetProgenitorStem CellsMutantAffectTranscriptome

Grant awards (62)

Mechanisms of granulocyte homeostasis$728,731
R01 · FY2025 · HL · contact PI
Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)$652,141
R01 · FY2025 · CA
Modeling myelodysplasia$578,295
R01 · FY2025 · CA · contact PI
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesis$1,019,079
RC2 · FY2024 · DK · contact PI
Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)$622,018
R01 · FY2024 · CA
Modeling myelodysplasia$554,506
R01 · FY2024 · CA · contact PI
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesis$1,061,539
RC2 · FY2023 · DK · contact PI
Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)$687,428
R01 · FY2023 · CA
Modeling myelodysplasia$577,146
R01 · FY2023 · CA · contact PI
Mechanisms of granulocyte homeostasis$575,239
R01 · FY2023 · HL · contact PI
Regulation of functionally discrete hematopietic stem cells$574,491
R01 · FY2023 · DK · contact PI
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesis$1,061,539
RC2 · FY2022 · DK · contact PI
Modeling myelodysplasia$592,469
R01 · FY2022 · CA · contact PI
Regulation of functionally discrete hematopietic stem cells$579,663
R01 · FY2022 · DK · contact PI
Mechanisms of granulocyte homeostasis$576,001
R01 · FY2022 · HL · contact PI
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesis$1,061,539
RC2 · FY2021 · DK · contact PI
Modeling myelodysplasia$614,181
R01 · FY2021 · CA · contact PI
Regulation of functionally discrete hematopietic stem cells$587,152
R01 · FY2021 · DK · contact PI
Mechanisms of granulocyte homeostasis$576,671
R01 · FY2021 · HL · contact PI
Infectious pressures on cell competition and cooperation during leukemia initiation$408,829
R21 · FY2021 · CA · contact PI
Defining human hematopoietic cells via transcriptomes and methods to isolate them$266,476
R21 · FY2021 · HL · contact PI
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesis$1,061,540
RC2 · FY2020 · DK · contact PI
Mechanisms of granulocyte homeostasis$592,095
R01 · FY2020 · HL · contact PI
Regulation of functionally discrete hematopietic stem cells$592,073
R01 · FY2020 · DK · contact PI
Defining human hematopoietic cells via transcriptomes and methods to isolate them$198,750
R21 · FY2020 · HL · contact PI
Transition states in lineage specification$198,750
R21 · FY2019 · AI · contact PI
A rapid spontaneous murine model of CN-AML$567,086
R01 · FY2018 · CA · contact PI
Mechanisms of granulocyte homeostasis$390,000
R01 · FY2018 · HL · contact PI
Transition states in lineage specification$238,500
R21 · FY2018 · AI · contact PI
A rapid spontaneous murine model of CN-AML$219,775
R01 · FY2018 · CA · contact PI
A rapid spontaneous murine model of CN-AML$575,500
R01 · FY2017 · CA · contact PI
Mechanisms of granulocyte homeostasis$390,000
R01 · FY2017 · HL · contact PI
A rapid spontaneous murine model of CN-AML$234,525
R01 · FY2017 · CA · contact PI
A rapid spontaneous murine model of CN-AML$625,379
R01 · FY2016 · CA · contact PI
Mechanisms of granulocyte homeostasis$390,000
R01 · FY2016 · HL · contact PI
Mechanisms of granulocyte homeostasis$390,000
R01 · FY2015 · HL · contact PI
MicroRNA in Acute Myeloid Leukemia$317,475
R01 · FY2015 · CA · contact PI
Developing Novel STAT5 Protein Inhibitors for treatment of leukemias$162,221
R21 · FY2015 · CA · contact PI
MicroRNA in Acute Myeloid Leukemia$307,951
R01 · FY2014 · CA · contact PI
Developing Novel STAT5 Protein Inhibitors for treatment of leukemias$169,650
R21 · FY2014 · CA · contact PI
MicroRNA in Acute Myeloid Leukemia$298,427
R01 · FY2013 · CA · contact PI
MicroRNA in Acute Myeloid Leukemia$317,475
R01 · FY2012 · CA · contact PI
MicroRNA in Acute Myeloid Leukemia$317,475
R01 · FY2011 · CA · contact PI
Epigenetic manipulation of Leukemia$165,000
R21 · FY2010 · CA · contact PI
Molecular Mechanism of Severe Congenital Neutropenia$242,753
R01 · FY2009 · HL · contact PI
A Molecular Basis for Neuroendocrine Carcinogenesis$233,253
R01 · FY2009 · CA · contact PI
Epigenetic manipulation of Leukemia$209,571
R21 · FY2009 · CA · contact PI
Molecular Mechanism of Severe Congenital Neutropenia$355,568
R01 · FY2008 · HL · contact PI
A Molecular Basis for Neuroendocrine Carcinogenesis$233,253
R01 · FY2008 · CA · contact PI
Molecular Mechanism of Severe Congenital Neutropenia$355,568
R01 · FY2007 · HL · contact PI
Transcriptional repression in leukemia$248,898
R01 · FY2007 · CA · contact PI
A Molecular Basis for Neuroendocrine Carcinogenesis$233,253
R01 · FY2007 · CA · contact PI
Molecular Mechanism of Severe Congenital Neutropenia$366,188
R01 · FY2006 · HL · contact PI
Transcriptional repression in leukemia$256,190
R01 · FY2006 · CA · contact PI
A Molecular Basis for Neuroendocrine Carcinogenesis$239,885
R01 · FY2006 · CA · contact PI
Molecular Mechanism of Severe Congenital Neutropenia$367,121
R01 · FY2005 · HL
Molecular Mechanism of Severe Congenital Neutropenia$358,493
R01 · FY2005 · HL
Transcriptional repression in leukemia$252,017
R01 · FY2005 · CA
A Molecular Basis for Neuroendocrine Carcinogenesis$240,769
R01 · FY2005 · CA
Transcriptional repression in leukemia$10,936
R01 · FY2005 · CA
Molecular Mechanism of Severe Congenital Neutropenia$367,121
R01 · FY2004 · HL
Transcriptional repression in leukemia$257,029
R01 · FY2004 · CA