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Xin Chen

University Of Hawaii At Manoa

$14,864,120
Attributed
$19,470,350
Total exposure
23
Grants
18
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.9M · FY200525
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$19,470,350 · 23

By mechanism

R01$13,806,189 · 6
R21$2,863,176 · 8
R03$779,741 · 5
K01$722,250 · 1
UG3$657,145 · 1
R43$348,747 · 1

Top collaborators

Most similar at University Of Hawaii At Manoa

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsPathway InteractionsTumorIn VivoSamplingLiverMolecularMalignant Neoplasm Of LiverPrimary Carcinoma Of The Liver CellsSignal TransductionPathogenesisIn VitroLiver NeoplasmsOncogenesMediatingGenesSignal PathwayInsightMouse ModelCellsBaseOverexpressionIncidenceGene Expression

Grant awards (70)

Investigating multifactorial beta-catenin activation in hepatocellular cancers$490,219
R01 · FY2025 · CA · contact PI
Targeting CXCR2+ PMN-MDSCs for immunotherapy of hepatoblastoma$402,400
R21 · FY2025 · CA · contact PI
Discovery of novel natural TEAD inhibitors for the chemoprevention of liver tumors$322,891
UG3 · FY2025 · CA
Cancer Biology Research Program$219,100
P30 · FY2025 · CA · contact PI
Investigating multifactorial beta-catenin activation in hepatocellular cancers$465,707
R01 · FY2024 · CA · contact PI
Signaling pathways during hepatocarcinogenesis$340,095
R01 · FY2024 · CA · contact PI
Discovery of novel natural TEAD inhibitors for the chemoprevention of liver tumors$334,254
UG3 · FY2024 · CA
Cancer Biology Research Program$74,002
P30 · FY2024 · CA · contact PI
Investigating multifactorial beta-catenin activation in hepatocellular cancers$480,413
R01 · FY2023 · CA · contact PI
Signaling pathways during hepatocarcinogenesis$350,834
R01 · FY2023 · CA · contact PI
Role of Cancer-Associated Fibroblasts in Cholangiocarcinoma$609,144
R01 · FY2022 · CA
Signaling pathways during hepatocarcinogenesis$350,460
R01 · FY2022 · CA · contact PI
Investigating multifactorial beta-catenin activation in hepatocellular cancers$324,555
R01 · FY2022 · CA · contact PI
Investigating multifactorial beta-catenin activation in hepatocellular cancers$166,859
R01 · FY2022 · CA · contact PI
Role of Cancer-Associated Fibroblasts in Cholangiocarcinoma$621,575
R01 · FY2021 · CA
Investigating multifactorial beta-catenin activation in hepatocellular cancers$511,819
R01 · FY2021 · CA · contact PI
Signaling pathways during hepatocarcinogenesis$369,431
R01 · FY2021 · CA · contact PI
Cabozentinib based combination therapy for the treatment of hepatocellular carcinoma$80,750
R03 · FY2021 · CA · contact PI
Role of Cancer-Associated Fibroblasts in Cholangiocarcinoma$621,461
R01 · FY2020 · CA
Yap and beta-catenin interactions in liver: Implications in Pathophysiology$420,055
R01 · FY2020 · CA
Signaling pathways during hepatocarcinogenesis$368,669
R01 · FY2020 · CA · contact PI
Signaling cascades in cholangiocarcinoma development$362,569
R01 · FY2020 · CA · contact PI
Cabozentinib based combination therapy for the treatment of hepatocellular carcinoma$80,626
R03 · FY2020 · CA · contact PI
Role of Cancer-Associated Fibroblasts in Cholangiocarcinoma$601,544
R01 · FY2019 · CA
Yap and beta-catenin interactions in liver: Implications in Pathophysiology$407,169
R01 · FY2019 · CA
Signaling cascades in cholangiocarcinoma development$351,691
R01 · FY2019 · CA · contact PI
Role of Cancer-Associated Fibroblasts in Cholangiocarcinoma$634,470
R01 · FY2018 · CA
Yap and beta-catenin interactions in liver: Implications in Pathophysiology$416,268
R01 · FY2018 · CA
Signaling cascades in cholangiocarcinoma development$362,569
R01 · FY2018 · CA · contact PI
SWI/SNF complex in mouse HCC development$79,250
R03 · FY2018 · CA · contact PI
Inducible systems for studying liver tumor mainenance in vivo$79,250
R03 · FY2018 · CA · contact PI
Yap and beta-catenin interactions in liver: Implications in Pathophysiology$414,072
R01 · FY2017 · CA
Signaling cascades in cholangiocarcinoma development$362,569
R01 · FY2017 · CA · contact PI
SWI/SNF complex in mouse HCC development$79,250
R03 · FY2017 · CA · contact PI
Inducible systems for studying liver tumor mainenance in vivo$79,250
R03 · FY2017 · CA · contact PI
Yap and beta-catenin interactions in liver: Implications in Pathophysiology$425,315
R01 · FY2016 · CA
Signaling cascades in cholangiocarcinoma development$362,569
R01 · FY2016 · CA · contact PI
Molecular Genetics of Liver Cancers$356,625
R01 · FY2016 · CA · contact PI
Glutamine catabolism in c-Myc driven liver tumor development$206,843
R21 · FY2016 · CA · contact PI
Molecular Genetics of Liver Cancers$356,625
R01 · FY2015 · CA · contact PI
Fatty acid transporters in cholangiocarcinoma pathogenesis$205,864
R21 · FY2015 · CA · contact PI
Glutamine catabolism in c-Myc driven liver tumor development$172,324
R21 · FY2015 · CA · contact PI
Molecular Genetics of Liver Cancers$355,688
R01 · FY2014 · CA · contact PI
Fatty acid transporters in cholangiocarcinoma pathogenesis$171,010
R21 · FY2014 · CA · contact PI
Molecular Genetics of Liver Cancers$13,000
R01 · FY2014 · CA · contact PI
Molecular Genetics of Liver Cancers$287,938
R01 · FY2013 · CA · contact PI
Lipogenic inhibitors in prevention of oncogene induced liver cancer$72,615
R03 · FY2013 · CA · contact PI
Molecular Genetics of Liver Cancers$306,316
R01 · FY2012 · CA · contact PI
Genetic Alterations Promoting Alcohol Induced Hepatic Carcinogenesis$222,094
R21 · FY2012 · AA · contact PI
Virus-gene interactions during hepatic carcinogenesis$201,623
R21 · FY2012 · CA · contact PI
Lipogenic inhibitors in prevention of oncogene induced liver cancer$77,250
R03 · FY2012 · CA · contact PI
Molecular Genetics of Liver Cancers$306,316
R01 · FY2011 · CA · contact PI
Genetic Alterations Promoting Alcohol Induced Hepatic Carcinogenesis$183,469
R21 · FY2011 · AA · contact PI
Virus-gene interactions during hepatic carcinogenesis$168,019
R21 · FY2011 · CA · contact PI
Molecular Genetics of Liver Cancers$315,790
R01 · FY2010 · CA · contact PI
Targeted siRNA Delivery to Liver with EIT guided Sonoporation$348,747
R43 · FY2009 · AA
Molecular Genetics of Liver Cancers$315,790
R01 · FY2009 · CA · contact PI
A flexible somatic and sporadic mouse model for liver cancers$203,667
R21 · FY2009 · CA · contact PI
A flexible somatic and sporadic mouse model for liver cancers$168,905
R21 · FY2008 · CA · contact PI
Gene Expression Profiles in Human Liver Cancers$148,770
K01 · FY2007 · CA · contact PI
Gene Expression Profiles in Human Liver Cancers$148,770
K01 · FY2006 · CA · contact PI
Expression Programs of Intestinal Cell Differentiation$147,940
R21 · FY2006 · DK · contact PI
Hedgehog signaling in human hepatocellular carcinoma$127,228
R21 · FY2006 · CA · contact PI
Expression Programs of Intestinal Cell Differentiation$151,500
R21 · FY2005 · DK
Gene Expression Profiles in Human Liver Cancers$148,770
K01 · FY2005 · CA
Hedgehog signaling in human hepatocellular carcinoma$130,290
R21 · FY2005 · CA
Expression patterns of gastric premalignant lesions$75,750
R03 · FY2005 · CA
Gene Expression Profiles in Human Liver Cancers$148,770
K01 · FY2004 · CA
Expression patterns of gastric premalignant lesions$75,750
R03 · FY2004 · CA
Gene Expression Profiles in Human Liver Cancers$127,170
K01 · FY2003 · CA