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Jiandong Chen

H. Lee Moffitt Cancer Ctr & Res Inst

$17,685,452
Attributed
$20,831,536
Total exposure
14
Grants
9
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.4M · FY200525
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$20,831,536 · 14

By mechanism

R01$18,829,755 · 11
P01$1,580,271 · 1
R21$411,510 · 1
R13$10,000 · 1

Top collaborators

Most similar at H. Lee Moffitt Cancer Ctr & Res Inst

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsResponseTp53 GeneTumorRegulationPhosphorylationDna DamageTumor Suppressor ProteinsMdm2 GeneSignal TransductionIn VivoStressCancer TherapyDna BindingMediatingLeadCellsApoptosisNovel StrategiesPathway InteractionsResearch StudyResistanceMutantBiological Adaptation To Stress

Grant awards (71)

Selective targeting of TAF1 function in acute myeloid leukemia$635,624
R01 · FY2025 · CA
Anti-tumor potential of temperature-sensitive p53 mutants$444,591
R01 · FY2025 · CA · contact PI
Allosteric Regulation of MDMX by Protein Disorder$338,330
R01 · FY2025 · CA · contact PI
Selective targeting of TAF1 function in acute myeloid leukemia$635,624
R01 · FY2024 · CA
Anti-tumor potential of temperature-sensitive p53 mutants$422,360
R01 · FY2024 · CA · contact PI
Allosteric Regulation of MDMX by Protein Disorder$321,415
R01 · FY2024 · CA · contact PI
Allosteric Regulation of MDMX by Protein Disorder$338,330
R01 · FY2023 · CA · contact PI
Regulation of transcriptional activation by protein disorder$320,214
R01 · FY2023 · GM
Regulation of transcriptional activation by protein disorder$51,191
R01 · FY2023 · GM
Anti-tumor potential of temperature-sensitive p53 mutants$1
R01 · FY2023 · CA · contact PI
Anti-tumor potential of temperature-sensitive p53 mutants$435,695
R01 · FY2022 · CA · contact PI
Allosteric Regulation of MDMX by Protein Disorder$382,811
R01 · FY2022 · CA · contact PI
Regulation of transcriptional activation by protein disorder$319,459
R01 · FY2022 · GM
Anti-tumor potential of temperature-sensitive p53 mutants$444,590
R01 · FY2021 · CA · contact PI
Regulation of transcriptional activation by protein disorder$318,706
R01 · FY2021 · GM
Regulation of transcriptional activation by protein disorder$330,442
R01 · FY2020 · GM
Function and regulation of MDMX intra-molecular interactions$381,646
R01 · FY2019 · CA · contact PI
Mechanisms of p53 activation during stress response (MPI)$365,293
R01 · FY2019 · CA · contact PI
Function and regulation of MDMX intra-molecular interactions$393,450
R01 · FY2018 · CA · contact PI
Mechanisms of p53 activation during stress response (MPI)$376,591
R01 · FY2018 · CA · contact PI
The 9th International MDM2 Workshop$10,000
R13 · FY2018 · CA · contact PI
Function and regulation of MDMX intra-molecular interactions$393,450
R01 · FY2017 · CA · contact PI
Mechanisms of p53 activation during stress response (MPI)$376,591
R01 · FY2017 · CA · contact PI
New approaches to target protein intramolecular interactions$187,050
R21 · FY2017 · CA · contact PI
Function and regulation of MDMX intra-molecular interactions$393,450
R01 · FY2016 · CA · contact PI
Mechanisms of p53 activation during stress response (MPI)$370,336
R01 · FY2016 · CA · contact PI
New approaches to target protein intramolecular interactions$224,460
R21 · FY2016 · CA · contact PI
Mechanisms of p53 activation during stress response (MPI)$387,461
R01 · FY2015 · CA · contact PI
Function and regulation of MDMX intra-molecular interactions$385,444
R01 · FY2015 · CA · contact PI
Function and regulation of MDMX$256,558
R01 · FY2014 · CA · contact PI
Mechanisms of p53 activation during stress response$315,962
R01 · FY2013 · CA · contact PI
Function and regulation of MDMX$287,378
R01 · FY2013 · CA · contact PI
Mechanisms of p53 activation during stress response$336,129
R01 · FY2012 · CA · contact PI
Function and regulation of MDMX$264,493
R01 · FY2012 · CA · contact PI
Mechanisms of p53 activation during stress response$336,129
R01 · FY2011 · CA · contact PI
Targeting of MDM2 Family Proteins in Cancer$312,894
P01 · FY2011 · CA · contact PI
Function and regulation of SirT1 in cancer$277,003
R01 · FY2011 · CA · contact PI
Function and regulation of MDMX$264,493
R01 · FY2011 · CA · contact PI
Mechanisms of p53 activation during stress response$346,525
R01 · FY2010 · CA · contact PI
Targeting of MDM2 Family Proteins in Cancer$336,925
P01 · FY2010 · CA · contact PI
Function and regulation of SirT1 in cancer$285,570
R01 · FY2010 · CA · contact PI
Function and regulation of MDMX$272,673
R01 · FY2010 · CA · contact PI
Mechanisms of p53 activation during stress response$346,525
R01 · FY2009 · CA · contact PI
Targeting of MDM2 Family Proteins in Cancer$329,392
P01 · FY2009 · CA · contact PI
Function and regulation of SirT1 in cancer$285,428
R01 · FY2009 · CA · contact PI
Targeting of MDM2 Family Proteins in Cancer$305,067
P01 · FY2008 · CA · contact PI
Function and regulation of SirT1 in cancer$283,860
R01 · FY2008 · CA · contact PI
Function and Regulation of MDMX$258,133
R01 · FY2008 · CA · contact PI
Targeting of MDM2 Family Proteins in Cancer$295,993
P01 · FY2007 · CA · contact PI
Function and regulation of SirT1 in cancer$283,860
R01 · FY2007 · CA · contact PI
Pharmacological rescue of mutant p53 function$275,105
R01 · FY2007 · CA · contact PI
Function and Regulation of MDMX$241,499
R01 · FY2007 · CA · contact PI
Pharmacological rescue of mutant p53 function$283,322
R01 · FY2006 · CA · contact PI
Function and Regulation of MDMX$261,038
R01 · FY2006 · CA · contact PI
Function and Regulation of MDMX$47,246
R01 · FY2006 · CA · contact PI
Pharmacological rescue of mutant p53 function$290,140
R01 · FY2005 · CA
Function and Regulation of MDMX$267,320
R01 · FY2005 · CA
Stabilization of MDM2 by mutant p53$241,063
R01 · FY2005 · CA
Function and Regulation of MDMX$47,246
R01 · FY2005 · CA
Function and Regulation of MDMX$25,296
R01 · FY2005 · CA
Pharmacological rescue of mutant p53 function$290,140
R01 · FY2004 · CA
Function and Regulation of MDMX$267,320
R01 · FY2004 · CA
Stabilization of MDM2 by mutant p53$241,063
R01 · FY2004 · CA
Pharmacological rescue of mutant p53 function$286,432
R01 · FY2003 · CA
Stabilization of MDM2 by mutant p53$241,063
R01 · FY2003 · CA
REGULATION OF P53 SUBCELLULAR DISTRIBUTION BY MDM2/ARF$209,806
R01 · FY2003 · CA
Stabilization of MDM2 by mutant p53$241,063
R01 · FY2002 · CA
REGULATION OF P53 SUBCELLULAR DISTRIBUTION BY MDM2/ARF$203,696
R01 · FY2002 · CA
REGULATION OF P53 SUBCELLULAR DISTRIBUTION BY MDM2/ARF$197,763
R01 · FY2001 · CA
PROTEOLYTIC CLEAVAGE OF MDM2 DURING APOPTOSIS$216,318
R01 · FY2000 · CA
REGULATION OF P53 SUBCELLULAR DISTRIBUTION BY MDM2/ARF$192,002
R01 · FY2000 · CA