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Brian K Kobilka

Stanford University

$34,154,790
Attributed
$39,594,327
Total exposure
17
Grants
13
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.4M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$45,868,998 · 18

By mechanism

R01$22,068,828 · 5
U19$10,211,021 · 3
R37$8,095,730 · 2
UG3$2,664,000 · 1
R21$1,415,200 · 4
R35$1,255,674 · 1

Top collaborators

Most similar at Stanford University

Same institution · by research overlap

Others in their field

Top investigators on “Structure

Research focus

StructureG-Protein-Coupled ReceptorsReceptorPharmaceutical PreparationsLigandsGtp-Binding ProteinsComplexBaseSignal TransductionFamilyAgonistProteinsResolutionPropertyBehaviorInflammationInsightHormonesCardiovascular DiseasesCellsCouplingHuman GenomeMembrane ProteinsNeurotransmitters

Grant awards (95)

Development of negative allosteric modulators at the mu opioid receptor$2,664,000
UG3 · FY2025 · DA
G protein coupled receptor structure, dynamics, and signaling.$627,837
R35 · FY2025 · NS · contact PI
The structural basis for pathway-selective signaling by the µ opioid receptor$540,607
R01 · FY2025 · DA · contact PI
G protein coupled receptor structure, dynamics, and signaling.$627,837
R35 · FY2024 · NS · contact PI
The structural basis for pathway-selective signaling by the µ opioid receptor$549,378
R01 · FY2024 · DA · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$472,743
R01 · FY2023 · GM
Structure and dynamics of G protein coupled receptor-G protein complexes$69,045
R01 · FY2023 · GM
Structure and dynamics of G protein coupled receptor-G protein complexes$476,217
R01 · FY2022 · GM
G Protein Coupled Receptor Structure, Dynamics and Signaling$544,920
R01 · FY2021 · NS · contact PI
Structural Basis of Opioid Receptor Function$616,324
R37 · FY2020 · DA · contact PI
G Protein Coupled Receptor Structure, Dynamics and Signaling$544,920
R01 · FY2020 · NS · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$502,225
R01 · FY2020 · GM
G Protein Coupled Receptor Structure, Dynamics and Signaling$544,920
R01 · FY2019 · NS · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$474,061
R01 · FY2019 · GM
Structural Basis of Opioid Receptor Function$465,649
R37 · FY2019 · DA · contact PI
Structural Basis of Opioid Receptor Function$152,588
R37 · FY2019 · DA · contact PI
G Protein Coupled Receptor Structure, Dynamics and Signaling$544,920
R01 · FY2018 · NS · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$477,909
R01 · FY2018 · GM
Structural Basis of Opioid Receptor Function$467,467
R37 · FY2018 · DA · contact PI
Structural Basis of Opioid Receptor Function$153,860
R37 · FY2018 · DA · contact PI
Structure-based discovery of allosteric ligands for G Protein Coupled Receptors$1,239,663
U19 · FY2017 · GM · contact PI
Structural Basis of Protease-Activated Receptor Function$706,394
R01 · FY2017 · HL
Structural Insights into Allosteric Regulation G Protein$564,439
U19 · FY2017 · GM · contact PI
G Protein Coupled Receptor Structure, Dynamics and Signaling$544,920
R01 · FY2017 · NS · contact PI
Structural Basis of Opioid Receptor Function$497,320
R37 · FY2017 · DA · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$481,646
R01 · FY2017 · GM
Structure-Based Allosteric Ligand Discovery$219,981
U19 · FY2017 · GM · contact PI
Structure-based discovery of allosteric ligands for G Protein Coupled Receptors$1,239,663
U19 · FY2016 · GM · contact PI
Structural Basis of Protease-Activated Receptor Function$718,031
R01 · FY2016 · HL
Beta2 Adrenoceptor Structure and Mechanism of Activation$600,124
R01 · FY2016 · NS · contact PI
Structural Insights into Allosteric Regulation G Protein$564,439
U19 · FY2016 · GM · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$499,022
R01 · FY2016 · GM
Structural Basis of Opioid Receptor Function$449,447
R37 · FY2016 · DA · contact PI
Structure-Based Allosteric Ligand Discovery$219,981
U19 · FY2016 · GM · contact PI
Structure-based discovery of allosteric ligands for G Protein Coupled Receptors$1,239,747
U19 · FY2015 · GM · contact PI
Structural Basis of Protease-Activated Receptor Function$724,313
R01 · FY2015 · HL
Beta2 Adrenoceptor Structure and Mechanism of Activation$604,797
R01 · FY2015 · NS · contact PI
Structural Insights into Allosteric Regulation G Protein$564,439
U19 · FY2015 · GM · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$555,034
R01 · FY2015 · GM · contact PI
Structural Basis of Opioid Receptor Function$447,176
R37 · FY2015 · DA · contact PI
Structure-Based Allosteric Ligand Discovery$219,981
U19 · FY2015 · GM · contact PI
Structure-based discovery of allosteric ligands for G Protein Coupled Receptors$1,240,674
U19 · FY2014 · GM · contact PI
Structural Basis of Protease-Activated Receptor Function$774,725
R01 · FY2014 · HL
Beta2 Adrenoceptor Structure and Mechanism of Activation$598,263
R01 · FY2014 · NS · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$567,538
R01 · FY2014 · GM · contact PI
Structural Insights into Allosteric Regulation G Protein$564,439
U19 · FY2014 · GM · contact PI
Structural Basis of Opioid Receptor Function$453,987
R37 · FY2014 · DA · contact PI
Structure-Based Allosteric Ligand Discovery$219,981
U19 · FY2014 · GM · contact PI
Structure-based discovery of allosteric ligands for G Protein Coupled Receptors$1,314,924
U19 · FY2013 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$582,691
R01 · FY2013 · NS · contact PI
Structural Insights into Allosteric Regulation G Protein$564,439
U19 · FY2013 · GM · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$559,445
R01 · FY2013 · GM · contact PI
Structural Basis of Opioid Receptor Function$482,487
R37 · FY2013 · DA · contact PI
Structure-Based Allosteric Ligand Discovery$234,231
U19 · FY2013 · GM · contact PI
Structure and dynamics of G protein coupled receptor-G protein complexes$600,190
R01 · FY2012 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$583,346
R01 · FY2012 · NS · contact PI
Beta Adrenoceptor Signaling Complexes in Innervated Cardiac Myocytes$394,533
R01 · FY2012 · HL · contact PI
Crystallization and structure determination of the angiotensin II type 1 receptor$157,450
R21 · FY2012 · HL · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$593,965
R37 · FY2011 · NS · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$476,647
R01 · FY2011 · GM · contact PI
Beta Adrenoceptor Signaling Complexes in Innervated Cardiac Myocytes$398,383
R01 · FY2011 · HL · contact PI
Crystallization and structure determination of the angiotensin II type 1 receptor$286,200
R21 · FY2011 · HL · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$75,000
R01 · FY2011 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$596,223
R37 · FY2010 · NS · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$481,656
R01 · FY2010 · GM · contact PI
Beta Adrenoceptor Signaling Complexes in Innervated Cardiac Myocytes$398,253
R01 · FY2010 · HL · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$66,000
R01 · FY2010 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$586,989
R37 · FY2009 · NS · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$472,551
R01 · FY2009 · GM · contact PI
Beta Adrenoceptor Signaling Complexes in Innervated Cardiac Myocytes$398,127
R01 · FY2009 · HL · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$533,880
R37 · FY2008 · NS · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$473,486
R01 · FY2008 · GM · contact PI
Beta Adrenoceptor Signaling Complexes in Innervated Cardiac Myocytes$398,007
R01 · FY2008 · HL · contact PI
Production of 15N and 13C labeled GPCRs for NMR Spectroscopy$177,750
R21 · FY2008 · MH · contact PI
Structure and Dynamics of Beta 2 Adrenoceptor Coupling to Gs$66,900
R01 · FY2008 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$533,861
R37 · FY2007 · NS · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$533,790
R37 · FY2006 · NS · contact PI
Chimeric Proteins to Enhance Crystal Formation of G Protein Coupled Receptors (RM$209,460
R21 · FY2006 · GM · contact PI
FLUORESCENCE OF RHODAMINE LABELED BETA2 ADRENERGIC RECEPTOR$51,871
P41 · FY2006 · RR · contact PI
Chimeric Proteins to Enhance Crystal Formation of G Protein Coupled Receptors$49,840
R21 · FY2006 · GM · contact PI
Beta2 Adrenoceptor Structure and Mechanism of Activation$530,717
R37 · FY2005 · NS
B ADRENOCEPTOR SIGNALING COMPLEXES IN CARDIAC MYOCYTES$399,238
R01 · FY2005 · HL
Chimeric Proteins-Enhance Crystal Formation-G Prot(RMI)$214,500
R21 · FY2005 · GM
Biophysical Analysis of Opioid Receptor Structure$160,000
R21 · FY2005 · DA
FLUORESCENCE OF RHODAMINE LABELED BETA2 ADRENERGIC RECEPTOR$51,717
P41 · FY2005 · RR
B ADRENOCEPTOR SIGNALING COMPLEXES IN CARDIAC MYOCYTES$399,043
R01 · FY2004 · HL
THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION$223,883
R01 · FY2004 · NS
Biophysical Analysis of Opioid Receptor Structure$160,000
R21 · FY2004 · DA
FLUORESCENCE OF RHODAMINE LABELED BETA2 ADRENERGIC RECEPTOR$54,957
P41 · FY2004 · RR
B ADRENOCEPTOR SIGNALING COMPLEXES IN CARDIAC MYOCYTES$398,852
R01 · FY2003 · HL
THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION$217,361
R01 · FY2003 · NS
B ADRENOCEPTOR SIGNALING COMPLEXES IN CARDIAC MYOCYTES$273,735
R01 · FY2002 · HL
THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION$211,029
R01 · FY2002 · NS
THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION$204,883
R01 · FY2001 · NS
THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATION$198,917
R01 · FY2000 · NS