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Hengming Ke

University Of North Carolina Chapel Hill

$3,075,990
Attributed
$3,075,990
Total exposure
9
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $285.9K · FY200513
$500K$375K$250K$125K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13

Funding mix

By agency

NIH$3,075,990 · 9

By mechanism

R01$3,007,835 · 1
P41$68,155 · 8

Top collaborators

No co-investigators on record.

Most similar at University Of North Carolina Chapel Hill

Same institution · by research overlap

Others in their field

Top investigators on “Cyclic Amp

Research focus

Cyclic AmpPhosphodiesterase InhibitorsCyclic GmpEnzymesSildenafilSubstrate SpecificityProtein IsoformsFundingPhosphoric Diester HydrolasePharmaceutical PreparationsFamilyErectile DysfunctionBinding (Molecular Function)Inhibitor/AntagonistAbbott Brand Of Sildenafil CitrateGenesComplexInsightCatalytic DomainMutantStructureActive SitesHuman DiseaseBase

Grant awards (21)

Regulation, interaction, and inhibitor discovery of phosphodiesterases$266,642
R01 · FY2013 · GM · contact PI
Regulation, interaction, and inhibitor discovery of phosphodiesterases$276,312
R01 · FY2012 · GM · contact PI
Regulation, interaction, and inhibitor discovery of phosphodiesterases$276,312
R01 · FY2011 · GM · contact PI
Regulation, interaction, and inhibitor discovery of phosphodiesterases$279,103
R01 · FY2010 · GM · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES AND THEIR COMPLEXES WITH INHI$6,828
P41 · FY2010 · RR · contact PI
Substrate specificity and inhibitor selectivity of PDE$217,542
R01 · FY2009 · GM · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES AND THEIR COMPLEXES WITH INHI$10,049
P41 · FY2009 · RR · contact PI
Substrate specificity and inhibitor selectivity of PDE$234,661
R01 · FY2008 · GM · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES 10 AND 4 AND THEIR COMPLEXES$13,725
P41 · FY2008 · RR · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES 10 AND 4 AND THEIR COMPLEXES$4,575
P41 · FY2008 · RR · contact PI
Substrate specificity and inhibitor selectivity of PDE$234,661
R01 · FY2007 · GM · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES 10 AND 4 AND THEIR COMPLEXES$10,836
P41 · FY2007 · RR · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES 10 AND 4 AND THEIR COMPLEXES$3,611
P41 · FY2007 · RR · contact PI
Substrate specificity and inhibitor selectivity of PDE$241,669
R01 · FY2006 · GM · contact PI
3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FAMILIES 10 AND 4 AND THEIR COMPLEXES$7,871
P41 · FY2006 · RR · contact PI
Substrate specificity and inhibitor selectivity of PDE$247,485
R01 · FY2005 · GM
DATA COLLECTION ON PHOSPHODIESTERASE 4 IN COMPLEX WITH INHIBITORS$10,660
P41 · FY2005 · RR
CRYSTAL STRUCT. OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE$181,875
R01 · FY2003 · GM
CRYSTAL STRUCT. OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE$181,875
R01 · FY2002 · GM
CRYSTAL STRUCT. OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE$181,719
R01 · FY2001 · GM
CRYSTAL STRUCT. OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE$187,979
R01 · FY2000 · GM