John M Denu

Oregon Health And Science University

$18,836,664

Attributed

$21,732,773

Total exposure

Grants

Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3M · FY2005–25

$5M$3.8M$2.5M$1.3M$0

'05

'06

'07

'08

'09

'10

'11

'12

'13

'14

'15

'16

'17

'18

'19

'20

'21

'22

'23

'24

'25

Funding mix

By agency

NIH$23,004,279 · 13

By mechanism

R01$15,385,079 · 5

R37$3,703,945 · 1

R35$2,065,762 · 1

P30$1,668,516 · 2

R03$153,000 · 1

R13$26,500 · 2

Top collaborators

Others in their field

Top investigators on “Molecular”

David Heimbrook · Leidos Biomedical Research, Inc.$871,088,761
Leonard Freedman · Leidos Biomedical Research, Inc.$468,573,385
Richard Webby · St. Jude Children'S Research Hospital$254,843,170
Larry Arthur$238,531,074
Gregory H Reaman · National Childhood Cancer Foundation$230,630,913
Ralph Parchment · Leidos Biomedical Research, Inc.$193,231,914

Research focus

MolecularEnzymesProteinsLinkHistonesPathway InteractionsChromatinAcetylationBiochemicalMetabolismCellsMetabolicBaseResponseAcetyltransferaseBiologicalIn VitroRegulationLysineGeneticIn VivoPhosphorylationAgingPost-Translational Protein Processing

Grant awards (70)

Wisconsin Nathan Shock Center$1,271,506

P30 · FY2025 · AG

Dynamics and molecular mechanisms linking metabolism and the epigenome$698,211

R35 · FY2025 · GM · contact PI

The regulation of cancer and aging by methionine$606,677

R01 · FY2025 · AG

Wisconsin Nathan Shock Center$397,010

P30 · FY2025 · AG · contact PI

Dynamics and molecular mechanisms linking metabolism and the epigenome$698,211

R35 · FY2024 · GM · contact PI

The regulation of cancer and aging by methionine$625,589

R01 · FY2024 · AG

Dynamics and molecular mechanisms linking metabolism and the epigenome$669,340

R35 · FY2023 · GM · contact PI

The regulation of cancer and aging by methionine$619,736

R01 · FY2023 · AG

Dietary regulation of the hepatic epigenome$582,703

R01 · FY2023 · DK · contact PI

Dietary regulation of the hepatic epigenome$582,703

R01 · FY2022 · DK · contact PI

Reversible protein acetylation and sirtuin function$449,740

R01 · FY2022 · GM · contact PI

Molecular mechanisms of histone modification$341,677

R37 · FY2022 · GM · contact PI

Dietary regulation of the hepatic epigenome$588,860

R01 · FY2021 · DK · contact PI

Reversible protein acetylation and sirtuin function$449,740

R01 · FY2021 · GM · contact PI

Molecular mechanisms of histone modification$341,677

R37 · FY2021 · GM · contact PI

Reversible protein acetylation and sirtuin function$448,373

R01 · FY2020 · GM · contact PI

Molecular mechanisms of histone modification$341,677

R37 · FY2020 · GM · contact PI

Reversible protein acetylation and sirtuin function$67,359

R01 · FY2020 · GM · contact PI

Reversible protein acetylation and sirtuin function$448,373

R01 · FY2019 · GM · contact PI

Molecular mechanisms of histone modification$341,677

R37 · FY2019 · GM · contact PI

Reversible protein acetylation and sirtuin function$389,057

R01 · FY2018 · GM · contact PI

Molecular mechanisms of histone modification$341,677

R37 · FY2018 · GM · contact PI

Molecular mechanisms of histone modification - Alzheimerâs supplement NOT-AG-18-008$303,239

R37 · FY2018 · GM · contact PI

Reversible protein acetylation and sirtuin function$389,057

R01 · FY2017 · GM · contact PI

Molecular mechanisms of histone modification$309,263

R37 · FY2017 · GM · contact PI

Linking mitochondrial variation and lifespan amongst five species of Rodentia$76,500

R03 · FY2017 · AG · contact PI

Reversible protein acetylation and sirtuin function$389,057

R01 · FY2016 · GM · contact PI

Molecular mechanisms of histone modification$309,263

R37 · FY2016 · GM · contact PI

Linking mitochondrial variation and lifespan amongst five species of Rodentia$76,500

R03 · FY2016 · AG · contact PI

Administrative Supplement for Study the Role of Sirt3 in aging R01AG038679$68,500

R01 · FY2016 · AG

Reversible protein acetylation and sirtuin function$389,057

R01 · FY2015 · GM · contact PI

Molecular mechanisms of histone modification$309,263

R37 · FY2015 · GM · contact PI

Role of Sirt3 in Aging and Caloric Restriction$296,055

R01 · FY2015 · AG

Molecular mechanisms of histone modification$149,400

R37 · FY2015 · GM · contact PI

Reversible protein acetylation and sirtuin function$385,589

R01 · FY2014 · GM · contact PI

Molecular mechanisms of histone modification$307,566

R37 · FY2014 · GM · contact PI

Role of Sirt3 in Aging and Caloric Restriction$305,212

R01 · FY2014 · AG

Reversible protein acetylation and sirtuin function$372,034

R01 · FY2013 · GM · contact PI

Molecular mechanisms of histone modification$307,566

R37 · FY2013 · GM · contact PI

Role of Sirt3 in Aging and Caloric Restriction$288,426

R01 · FY2013 · AG

Reversible protein acetylation and sirtuin function$385,466

R01 · FY2012 · GM · contact PI

Role of Sirt3 in Aging and Caloric Restriction$305,212

R01 · FY2012 · AG

Molecular Mechanisms of Histone Acetyltransferases$296,060

R01 · FY2012 · GM · contact PI

Reversible protein acetylation and sirtuin function$386,016

R01 · FY2011 · GM · contact PI

Role of Sirt3 in Aging and Caloric Restriction$305,212

R01 · FY2011 · AG

Molecular Mechanisms of Histone Acetyltransferases$296,060

R01 · FY2011 · GM · contact PI

Molecular Mechanisms of Histone Acetyltransferases$302,279

R01 · FY2010 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$280,893

R01 · FY2010 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$123,239

R01 · FY2010 · GM · contact PI

Molecular Mechanisms of Histone Acetyltransferases$298,813

R01 · FY2009 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$283,730

R01 · FY2009 · GM · contact PI

Histone Deacetylases and reversible acetylation in signaling and disease$15,000

R13 · FY2009 · AG · contact PI

NAD Metabolism and Signaling Conference$11,500

R13 · FY2009 · DK · contact PI

SIRTUIN PROTEIN-HISTON DEACETYLASE STUDY$1,477

P41 · FY2009 · RR · contact PI

Reversible Protein Acetylation and Chromatin Function$283,730

R01 · FY2008 · GM · contact PI

Molecular Mechanisms of Histone Acetyltransferases$230,883

R01 · FY2008 · GM · contact PI

Molecular Mechanisms of Histone Acetyltransferases$230,988

R01 · FY2007 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$188,990

R01 · FY2007 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$94,740

R01 · FY2007 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$279,514

R01 · FY2006 · GM · contact PI

Molecular Mechanisms of Histone Acetyltransferases$237,994

R01 · FY2006 · GM · contact PI

Reversible Protein Acetylation and Chromatin Function$286,295

R01 · FY2005 · GM

Molecular Mechanisms of Histone Acetyltransferases$229,228

R01 · FY2005 · GM

Reversible Protein Acetylation and Chromatin Function$286,347

R01 · FY2004 · GM

Reversible Protein Acetylation and Chromatin Function$224,719

R01 · FY2003 · GM

MECHANISMS OF ERK INACTIVATION BY PROTEIN PHOSPHATASES$193,354

R01 · FY2003 · GM

Reversible Protein Acetylation and Chromatin Function$38,294

R01 · FY2003 · GM

MECHANISMS OF ERK INACTIVATION BY PROTEIN PHOSPHATASES$197,313

R01 · FY2002 · GM

MECHANISMS OF ERK INACTIVATION BY PROTEIN PHOSPHATASES$191,654

R01 · FY2001 · GM

MECHANISMS OF ERK INACTIVATION BY PROTEIN PHOSPHATASES$186,159

R01 · FY2000 · GM