← Leaderboards
William P Clarke
University Of Texas Hlth Sci Ctr San Ant
$10,604,907
Attributed
$13,652,532
Total exposure
14
Grants
12
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $1.5M · FY2007–25$2M$1.5M$1M$500K$0
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$13,652,532 · 14
By mechanism
R01$10,985,844 · 8
R21$1,670,821 · 4
R61$852,338 · 1
P01$143,529 · 1
Top collaborators
- Kelly Ann Berg11 shared
- Stanton Furst Mchardy3 shared
- James H Woods3 shared
Most similar at University Of Texas Hlth Sci Ctr San Ant
Same institution · by research overlap
- Kenneth M Hargreaves$34,502,152
- Asma A Khan$999,829
Others in their field
Top investigators on “Pain”
- Emer Leahy · Psychogenics, Inc.$49,781,254
- Lynn Larson Debar · Kaiser Foundation Research Institute$37,527,482
- J Richard Landis · University Of Pennsylvania$34,799,488
- Clifford J Woolf · Boston Children'S Hospital$30,992,766
- Emeran A Mayer · University Of California Los Angeles$29,229,798
- Pamela Susan Douglas · Duke University$28,862,172
Research focus
PainIn VivoRattusNeuronsPharmaceutical PreparationsMediatingAnalgesicsAfferent NeuronsRegulationPeripheralReceptorLeadAgonistResponseAdverse EffectsLigandsSignal TransductionNociceptorsPain ManagementBehavioralAdenylate CyclaseOpioid ReceptorOpioidAbsence Of Pain Sensation
Grant awards (47)
Identification of allosteric molecules for DOR-KOR heteromer-mediated peripheral analgesia$508,826
R01 · FY2025 · DA · contact PI
Identification of allosteric molecules for DOR-KOR heteromer-mediated peripheral analgesia$508,286
R01 · FY2024 · DA · contact PI
Development of a phenotypic screening assay for novel compounds that inhibit peripheral pain-sensing neurons$414,347
R61 · FY2024 · AT · contact PI
Negative allosteric modulators for bradykinin B1 receptors$193,750
R21 · FY2024 · AI · contact PI
Identification of allosteric molecules for DOR-KOR heteromer-mediated peripheral analgesia$557,766
R01 · FY2023 · DA · contact PI
Development of a phenotypic screening assay for novel compounds that inhibit peripheral pain-sensing neurons$437,991
R61 · FY2023 · AT · contact PI
Negative allosteric modulators for bradykinin B1 receptors$232,500
R21 · FY2023 · AI · contact PI
Pharmacological and behavioral effects of MCAM: a long-acting, μ opioid receptor antagonist for treatment of opioid overdose and opioid abuse disorder$461,788
R01 · FY2021 · DA · contact PI
Pharmacological and behavioral effects of MCAM: a long-acting, μ opioid receptor antagonist for treatment of opioid overdose and opioid abuse disorder$461,788
R01 · FY2020 · DA · contact PI
Pharmacological and behavioral effects of MCAM: a long-acting, μ opioid receptor antagonist for treatment of opioid overdose and opioid abuse disorder$461,788
R01 · FY2019 · DA · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$436,307
R01 · FY2019 · DA · contact PI
KOR Agonist Functional Selectivity in Peripheral Sensory Neurons$368,194
R01 · FY2019 · DA · contact PI
Sumatriptan and MOH: Differential 5-HT1R signaling in trigeminal nociceptors$190,625
R21 · FY2019 · NS · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$436,307
R01 · FY2018 · DA · contact PI
Sumatriptan and MOH: Differential 5-HT1R signaling in trigeminal nociceptors$228,750
R21 · FY2018 · NS · contact PI
KOR agonist functional Selectivity in peripheral sensory neurons$99,125
R01 · FY2018 · DA · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$40,600
R01 · FY2018 · DA · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$476,907
R01 · FY2017 · DA · contact PI
Regulation of Kappa opioid receptor-mediated signaling and peripheral analgesia$279,536
R01 · FY2017 · GM · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$431,943
R01 · FY2016 · DA · contact PI
Regulation of Kappa opioid receptor-mediated signaling and peripheral analgesia$279,536
R01 · FY2016 · GM · contact PI
Aging, peripheral pain and analgesia$190,625
R21 · FY2016 · AG · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$40,600
R01 · FY2016 · DA · contact PI
KOR agonist functional selectivity in peripheral sensory neurons$436,935
R01 · FY2015 · DA · contact PI
Regulation of Kappa opioid receptor-mediated signaling and peripheral analgesia$279,536
R01 · FY2015 · GM · contact PI
Aging, peripheral pain and analgesia$226,126
R21 · FY2015 · AG · contact PI
Regulation of DOR-KOR heteromer formation in pain-sensing neurons$184,195
R21 · FY2015 · DA · contact PI
Regulation of Kappa opioid receptor-mediated signaling and peripheral analgesia$279,536
R01 · FY2014 · GM · contact PI
Regulation of DOR-KOR heteromer formation in pain-sensing neurons$224,250
R21 · FY2014 · DA · contact PI
Regulation of Kappa opioid receptor-mediated signaling and peripheral analgesia$99,640
R01 · FY2014 · GM · contact PI
Regulation of opioid receptor function in trigeminal ganglion$320,861
R01 · FY2012 · DA · contact PI
Regulation of opioid receptor function in trigeminal ganglion$320,861
R01 · FY2011 · DA · contact PI
Estrogen regulation of inflammatory mediator signaling$318,347
R01 · FY2011 · NS · contact PI
Regulation of opioid receptor function in trigeminal ganglion$330,784
R01 · FY2010 · DA · contact PI
Estrogen regulation of inflammatory mediator signaling$321,596
R01 · FY2010 · NS · contact PI
Regulation of opioid receptor function in trigeminal ganglion$334,125
R01 · FY2009 · DA · contact PI
Estrogen regulation of inflammatory mediator signaling$324,024
R01 · FY2009 · NS · contact PI
Estrogen regulation of inflammatory mediator signaling$30,038
R01 · FY2009 · NS · contact PI
Estrogen regulation of inflammatory mediator signaling$323,750
R01 · FY2008 · NS · contact PI
Opioid Receptors and Cellular Signaling Mechanisms$143,529
P01 · FY2007 · DA · contact PI
REGULATION OF 5HT1A RECEPTOR FUNCTION$206,766
R01 · FY2003 · MH
NOVEL ACTIONS OF INVERSE AGONISTS$214,396
R01 · FY2002 · GM
REGULATION OF 5HT1A RECEPTOR FUNCTION$200,745
R01 · FY2002 · MH
NOVEL ACTIONS OF INVERSE AGONISTS$208,236
R01 · FY2001 · GM
REGULATION OF 5HT1A RECEPTOR FUNCTION$194,897
R01 · FY2001 · MH
NOVEL ACTIONS OF INVERSE AGONISTS$202,255
R01 · FY2000 · GM
REGULATION OF 5HT1A RECEPTOR FUNCTION$189,219
R01 · FY2000 · MH