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Thomas Lewis Poulos

University Of California Irvine

$19,477,156
Attributed
$19,907,103
Total exposure
12
Grants
10
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.3M · FY200523
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23

Funding mix

By agency

NIH$19,907,103 · 12

By mechanism

R01$15,331,908 · 5
R35$2,924,779 · 1
T32$859,894 · 1
S10$477,304 · 1
R21$218,082 · 1
P30$94,720 · 1

Top collaborators

Others in their field

Top investigators on “Heme

Research focus

HemeElectron TransportEnzymesStructureProteinsStructural BiologyComplexCytochrome P450Nitric Oxide SynthaseProtein Protein InteractionBaseDesignIronOxidation-ReductionReactionBinding (Molecular Function)CoupledBiologicalCrystallographyBinding SitesSiteAntibioticsInhibitor/AntagonistX Ray Crystallography

Grant awards (75)

Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$595,980
R35 · FY2023 · GM · contact PI
Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$595,980
R35 · FY2022 · GM · contact PI
Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$595,980
R35 · FY2021 · GM · contact PI
Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$595,980
R35 · FY2020 · GM · contact PI
Chemical and Structural Biology Program (CSB)$21,216
P30 · FY2020 · CA · contact PI
Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$475,976
R35 · FY2019 · GM · contact PI
Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesis$64,883
R35 · FY2019 · GM · contact PI
Chemical and Structural Biology Program (CSB)$21,216
P30 · FY2019 · CA · contact PI
Structural Studies on Nitric Oxide Synthase$609,260
R01 · FY2018 · GM · contact PI
Training Program in Chemical and Structural Biology$180,850
T32 · FY2018 · GM · contact PI
Chemical and Structural Biology Program (CSB)$21,215
P30 · FY2018 · CA · contact PI
Structural Studies on Nitric Oxide Synthase$609,260
R01 · FY2017 · GM · contact PI
Training Program in Chemical and Structural Biology$191,943
T32 · FY2017 · GM · contact PI
Chemical and Structural Biology Program (CSB)$12,185
P30 · FY2017 · CA · contact PI
Structural Studies on Nitric Oxide Synthase$609,260
R01 · FY2016 · GM · contact PI
Training Program in Chemical and Structural Biology$189,415
T32 · FY2016 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$51,191
R01 · FY2016 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$47,375
R01 · FY2016 · GM · contact PI
Chemical and Structural Biology Program (CSB)$18,888
P30 · FY2016 · CA · contact PI
Structural Studies on Nitric Oxide Synthase$609,260
R01 · FY2015 · GM · contact PI
Training Program in Chemical and Structural Biology$186,953
T32 · FY2015 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$7,905
R01 · FY2015 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$510,766
R01 · FY2014 · GM · contact PI
Diversity in Heme Protein Structure and Function$301,031
R01 · FY2014 · GM · contact PI
Training Program in Chemical and Structural Biology$110,733
T32 · FY2014 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$34,298
R01 · FY2014 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$301,283
R01 · FY2013 · GM · contact PI
Diversity in Heme Protein Structure and Function$300,056
R01 · FY2013 · GM · contact PI
Structural Studies on Cytochromes P450 and Related Proteins$269,574
R01 · FY2013 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$313,305
R01 · FY2012 · GM · contact PI
Diversity in Heme Protein Structure and Function$293,513
R01 · FY2012 · GM · contact PI
Structural Studies on Cytochromes P450 and Related Proteins$279,351
R01 · FY2012 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$314,265
R01 · FY2011 · GM · contact PI
Diversity in Heme Protein Structure and Function$293,986
R01 · FY2011 · GM · contact PI
Structural Studies on Cytochromes P450 and Related Proteins$279,351
R01 · FY2011 · GM · contact PI
Structural Studies on Cytochromes P450 and Related Proteins$313,525
R01 · FY2010 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$309,300
R01 · FY2010 · GM · contact PI
Diversity in Heme Protein Structure and Function$297,399
R01 · FY2010 · GM · contact PI
Acquisition of a Bruker X8 Prospector Protein X-ray Crystallography System$477,304
S10 · FY2009 · RR · contact PI
Diversity in Heme Protein Structure and Function$304,932
R01 · FY2009 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$275,620
R01 · FY2009 · GM · contact PI
Nitroxyl adducts as structural probes of oxygenase/substrate interactions$218,082
R21 · FY2009 · ES · contact PI
Structural Studies on Cytochrome P450 & Related Proteins$303,352
R01 · FY2008 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$276,234
R01 · FY2008 · GM · contact PI
Heme Enzyme Engineering$268,952
R01 · FY2008 · GM · contact PI
Structural Studies on Cytochrome P450 & Related Proteins$303,352
R01 · FY2007 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$274,844
R01 · FY2007 · GM · contact PI
Heme Enzyme Engineering$268,952
R01 · FY2007 · GM · contact PI
ULTRA-HIGH RESOLUTION STRUCTURE OF NATIVE AND ENZYME INTERMEDIATE OF CYTOCHROME$197
P41 · FY2007 · RR · contact PI
Structural Studies on Cytochrome P450 & Related Proteins$312,412
R01 · FY2006 · GM · contact PI
Heme Enzyme Engineering$276,984
R01 · FY2006 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$207,198
R01 · FY2006 · GM · contact PI
Structural Studies on Nitric Oxide Synthase$78,354
R01 · FY2006 · GM · contact PI
ULTRA-HIGH RESOLUTION STRUCTURE OF NATIVE AND ENZYME INTERMEDIATE OF CYTOCHROME$219
P41 · FY2006 · RR · contact PI
Structural Studies on Cytochrome P450 &Related Proteins$319,231
R01 · FY2005 · GM
Heme Enzyme Engineering$283,186
R01 · FY2005 · GM
Structural Studies on Nitric Oxide Synthase$234,810
R01 · FY2005 · GM
Structural Studies on Cytochrome P450 &Related Proteins$278,870
R01 · FY2004 · GM
Structural Studies on Nitric Oxide Synthase$233,785
R01 · FY2004 · GM
HEME ENZYME ENGINEERING$87,084
R01 · FY2004 · GM
Structural Studies on Cytochrome P450 &Related Proteins$278,386
R01 · FY2003 · GM
HEME ENZYME ENGINEERING$259,356
R01 · FY2003 · GM
Structural Studies on Nitric Oxide Synthase$233,996
R01 · FY2003 · GM
Structural Studies on Cytochrome P450 &Related Proteins$279,315
R01 · FY2002 · GM
NITROGENASE MECHANISM AND ASSEMBLY$261,426
R01 · FY2002 · GM
HEME ENZYME ENGINEERING$259,356
R01 · FY2002 · GM
Structural Studies on Nitric Oxide Synthase$252,689
R01 · FY2002 · GM
7 FE FDI AS A MODEL FE-S AND REGULATORY PROTEIN$238,534
R01 · FY2002 · GM
Structural Studies on Cytochrome P450 &Related Proteins$294,373
R01 · FY2001 · GM
HEME ENZYME ENGINEERING$259,356
R01 · FY2001 · GM
NITROGENASE MECHANISM AND ASSEMBLY$254,652
R01 · FY2001 · GM
STRUCTURAL STUDIES ON NITRIC OXIDE SYNTHASE$194,180
R01 · FY2001 · GM
HEME ENZYME ENGINEERING$321,912
R01 · FY2000 · GM
STRUCTURAL STUDIES ON CYTOCHROME P450 &RELATED PROTEINS$213,098
R01 · FY2000 · GM
STRUCTURAL STUDIES ON NITRIC OXIDE SYNTHASE$188,613
R01 · FY2000 · GM