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Laurence H Hurley

University Of Arizona

$12,099,261
Attributed
$13,523,875
Total exposure
11
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.2M · FY200519
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19

Funding mix

By agency

NIH$13,523,875 · 11

By mechanism

R01$9,320,725 · 5
P50$1,675,270 · 1
P30$866,229 · 1
R35$734,939 · 1
R41$701,714 · 2
R43$224,998 · 1

Top collaborators

Most similar at University Of Arizona

Same institution · by research overlap

Others in their field

Top investigators on “Gene Expression

Research focus

Gene ExpressionPharmaceutical PreparationsStructureBaseSmall MoleculeG-QuartetsElementsScreening ProcedureDesignPromotor (Genetics)C-Myc GenesMolecular TargetInsightDrug Design /Synthesis /ProductionTranscriptional RegulationMalignant NeoplasmsGenesCellsIntermolecular InteractionCancer CellBinding (Molecular Function)Genetic TranscriptionPlasmidsPrograms

Grant awards (47)

Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations.$401,714
R41 · FY2019 · NS · contact PI
DNA Quadruplex Control of hTERT Transcription: A New Therapy for Taxotere Resistant Prostate Cancer$300,000
R41 · FY2018 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$337,420
R01 · FY2014 · CA · contact PI
The Development of Novel Inhibitors of BCL2 Gene Expression as Anticancer Therape$224,998
R43 · FY2014 · CA
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$328,492
R01 · FY2013 · CA · contact PI
Molecular Modeling$155,902
P30 · FY2013 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$50,848
R01 · FY2013 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$351,112
R01 · FY2012 · CA · contact PI
Molecular Modeling$168,105
P30 · FY2012 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$54,091
R01 · FY2012 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$352,813
R01 · FY2011 · CA · contact PI
DRUG TARGETING OF G-QUADRAPLEX-NM23-H2 COMPLEX IN THE c-MYC PROMOTER$333,027
P50 · FY2011 · CA · contact PI
Establishing a molecular system for drug targeting of transcriptional control$296,970
R01 · FY2011 · GM · contact PI
Molecular Modeling$176,630
P30 · FY2011 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$54,092
R01 · FY2011 · CA · contact PI
G-Quadruplex-Mediated Transcriptional Regulation of PDGFR-??$393,649
R01 · FY2010 · CA · contact PI
DRUG TARGETING OF G-QUADRAPLEX-NM23-H2 COMPLEX IN THE c-MYC PROMOTER$349,627
P50 · FY2010 · CA · contact PI
Establishing a molecular system for drug targeting of transcriptional control$299,970
R01 · FY2010 · GM · contact PI
Molecular Modeling$187,100
P30 · FY2010 · CA · contact PI
DRUG TARGETING OF G-QUADRAPLEX-NM23-H2 COMPLEX IN THE c-MYC PROMOTER$342,587
P50 · FY2009 · CA · contact PI
Establishing a molecular system for drug targeting of transcriptional control$302,084
R01 · FY2009 · GM · contact PI
Establishing a molecular system for drug targeting of transcriptional control$296,123
R01 · FY2009 · GM · contact PI
Molecular Modeling$178,492
P30 · FY2009 · CA · contact PI
DRUG TARGETING OF G-QUADRAPLEX-NM23-H2 COMPLEX IN THE c-MYC PROMOTER$342,489
P50 · FY2008 · CA · contact PI
Establishing a molecular system for drug targeting of transcriptional control$302,000
R01 · FY2008 · GM · contact PI
DRUG TARGETING OF G-QUADRAPLEX-NM23-H2 COMPLEX IN THE c-MYC PROMOTER$307,540
P50 · FY2007 · CA · contact PI
G-Quadruplexes as Targets for Drug Design$49,179
R01 · FY2007 · CA · contact PI
Topoisomerase II Site-Directed Alkylation of DNA$329,166
R01 · FY2006 · CA · contact PI
G-Quadruplexes as Targets for Drug Design$326,480
R01 · FY2006 · CA · contact PI
G-Quadruplexes as Targets for Drug Design$46,499
R01 · FY2006 · CA · contact PI
Topoisomerase II Site-Directed Alkylation of DNA$337,088
R01 · FY2005 · CA
G-Quadruplexes as Targets for Drug Design$334,337
R01 · FY2005 · CA
G-Quadruplexes as Targets for Drug Design$45,008
R01 · FY2005 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$492,109
R01 · FY2004 · CA
Topoisomerase II Site-Directed Alkylation of DNA$337,088
R01 · FY2004 · CA
G-Quadruplexes as Targets for Drug Design$334,337
R01 · FY2004 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$448,799
R01 · FY2003 · CA
Topoisomerase II Site-Directed Alkylation of DNA$337,088
R01 · FY2003 · CA
G-Quadruplexes as Targets for Drug Design$334,337
R01 · FY2003 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$533,800
R01 · FY2002 · CA
Topoisomerase II Site-Directed Alkylation of DNA$337,088
R01 · FY2002 · CA
G-Quadruplexes as Targets for Drug Design$334,337
R01 · FY2002 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$450,645
R01 · FY2001 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$52,504
R01 · FY2001 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$679,290
R35 · FY2000 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$441,172
R01 · FY2000 · CA
NOVEL APPROACHES TO ANTITUMOR DRUG DESIGN$55,649
R35 · FY2000 · CA