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Toshihiro Shioda

Massachusetts General Hospital

$10,202,413
Attributed
$15,198,486
Total exposure
9
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2M · FY200525
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
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'21
'22
'23
'24
'25

Funding mix

By agency

NIH$15,198,486 · 9

By mechanism

R01$13,103,973 · 4
R21$2,094,513 · 5

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Affect

Research focus

AffectGenerationsMaleExposure ToPreventAdultPregnantSperm CellAnimalsEndocrine DisruptorsGenesTributyltinInsightPrenatalEpigenetic ProcessLinkObesogenObesityOffspringEpigenomicsDna MethylationFatty Acid Glycerol EstersGene ExpressionAdipose Tissue

Grant awards (35)

Environmental chemicals impair epigenetic suppression of the endogenous retrovirus HML-2 in human primordial germ cells, predisposing the next generation to malignancies through HML-2 reactivation$604,191
R01 · FY2025 · ES · contact PI
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$460,781
R01 · FY2025 · ES
Reconstituting human testicular germ cell neoplasia in situ (GCNIS) in vitro using iPSC-derived primordial germ cell-like cells (PGCLCs) and genetically engineered human testicular cancer cells$231,413
R21 · FY2025 · CA · contact PI
Cannabinoids as an environmental risk factor of testicular cancer: Assessment using cell culture models of human and mouse primordial germ cells and by exposure of pregnant mice$208,750
R21 · FY2025 · DA · contact PI
Chromatin contacts are germline-transmissable vehicles underlying epigenetic transgenerational inheritance$640,087
R01 · FY2024 · ES
Environmental chemicals impair epigenetic suppression of the endogenous retrovirus HML-2 in human primordial germ cells, predisposing the next generation to malignancies through HML-2 reactivation$620,940
R01 · FY2024 · ES · contact PI
Cannabinoids as an environmental risk factor of testicular cancer: Assessment using cell culture models of human and mouse primordial germ cells and by exposure of pregnant mice$264,750
R21 · FY2024 · DA · contact PI
Roles of the LTR5_Hs human-specific endogenous retroviruses in primordial germ cells$208,750
R21 · FY2024 · HD · contact PI
Applications of the long-term culture human primordial germ cell-like cells to toxicological assessments and mechanistic studies on chemically caused heritable human health threats$208,750
R21 · FY2024 · ES · contact PI
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$12,953
R01 · FY2024 · ES
Chromatin contacts are germline-transmissable vehicles underlying epigenetic transgenerational inheritance$660,457
R01 · FY2023 · ES
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$463,639
R01 · FY2023 · ES
Applications of the long-term culture human primordial germ cell-like cells to toxicological assessments and mechanistic studies on chemically caused heritable human health threats$250,500
R21 · FY2023 · ES · contact PI
Roles of the LTR5_Hs human-specific endogenous retroviruses in primordial germ cells$250,500
R21 · FY2023 · HD · contact PI
Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism$584,633
R01 · FY2022 · ES
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$466,372
R01 · FY2022 · ES
Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism$587,196
R01 · FY2021 · ES
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$469,032
R01 · FY2021 · ES
Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism$589,708
R01 · FY2020 · ES
Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liver$485,592
R01 · FY2020 · ES
Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism$596,380
R01 · FY2019 · ES
Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism$617,630
R01 · FY2018 · ES
Transgenerational inheritance of prenatal obesogen exposure$670,342
R01 · FY2017 · ES
Transgenerational inheritance of prenatal obesogen exposure$670,342
R01 · FY2016 · ES
Roles of Nuclear Receptors in Generation of Heritable Epimutations in Germ Cells$213,800
R21 · FY2016 · ES · contact PI
Transgenerational inheritance of prenatal obesogen exposure$670,342
R01 · FY2015 · ES
Roles of Nuclear Receptors in Generation of Heritable Epimutations in Germ Cells$257,300
R21 · FY2015 · ES · contact PI
Transgenerational inheritance of prenatal obesogen exposure$663,637
R01 · FY2014 · ES
Transgenerational inheritance of prenatal obesogen exposure$683,024
R01 · FY2013 · ES
Functions of MSG1 Family Transcription Activators$325,240
R01 · FY2005 · CA
Functions of MSG1 Family Transcription Activators$325,240
R01 · FY2004 · CA
Functions of MSG1 Family Transcription Activators$325,240
R01 · FY2003 · CA
Functions of MSG1 Family Transcription Activators$325,240
R01 · FY2002 · CA
FUNCTIONS OF MSG1 FAMILY TRANSCRIPTION ACTIVATORS$297,195
R01 · FY2001 · CA
FUNCTIONS OF MSG1 FAMILY TRANSCRIPTION ACTIVATORS$288,540
R01 · FY2000 · CA