GGrantIndex
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David Andrew Largaespada

University Of Minnesota Twin Cities

$17,551,730
Attributed
$22,045,864
Total exposure
21
Grants
15
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.3M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$41,225,834 · 23

By mechanism

R01$13,186,979 · 8
U54$10,150,248 · 3
P01$9,378,487 · 1
P50$2,474,096 · 2
UH3$2,148,196 · 1
UG3$1,523,236 · 1

Top collaborators

Most similar at University Of Minnesota Twin Cities

Same institution · by research overlap

Others in their field

Top investigators on “Tumor

Research focus

TumorMalignant NeoplasmsGeneticMutationGenesBaseGenetic ScreeningMouse ModelIn VivoPathway InteractionsCellsOncogenesNeoplasm MetastasisTumor ProgressionSleeping BeautyAnimalsLeadGrantMolecularAnimal ModelComplexProgramsCancer GeneticsIn Vitro

Grant awards (103)

Integrated Immune Engineering for Poor Prognosis Cancers$1,907,279
P01 · FY2025 · CA
Integrated Immune Engineering for Poor Prognosis Cancers$1,811,915
P01 · FY2024 · CA
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1$548,991
R01 · FY2024 · NS · contact PI
Integrated Immune Engineering for Poor Prognosis Cancers$1,869,132
P01 · FY2023 · CA
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention$770,000
UH3 · FY2023 · CA · contact PI
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1$571,785
R01 · FY2023 · NS · contact PI
Integrated Immune Engineering for Poor Prognosis Cancers$1,869,132
P01 · FY2022 · CA
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention$608,196
UH3 · FY2022 · CA · contact PI
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1$577,428
R01 · FY2022 · NS · contact PI
Integrated Immune Engineering for Poor Prognosis Cancers$1,921,029
P01 · FY2021 · CA
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention$770,000
UH3 · FY2021 · CA · contact PI
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1$582,915
R01 · FY2021 · NS · contact PI
Center for Modeling Tumor Cell Migration Mechanics$1,768,788
U54 · FY2020 · CA
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention$761,618
UG3 · FY2020 · CA · contact PI
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1$587,214
R01 · FY2020 · NS · contact PI
Core 2: Cell and Whole Animal Genome Engineering$40,293
U54 · FY2020 · CA · contact PI
Center for Modeling Tumor Cell Migration Mechanics$2,127,145
U54 · FY2019 · CA
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention$761,618
UG3 · FY2019 · CA · contact PI
Center for Modeling Tumor Cell Migration Mechanics$96,792
U54 · FY2019 · CA
Admin-Core-001$83,166
U54 · FY2019 · CA
Center for Modeling Tumor Cell Migration Mechanics$83,166
U54 · FY2019 · CA
Center for Modeling Tumor Cell Migration Mechanics$70,486
U54 · FY2019 · CA
Core 2: Cell and Whole Animal Genome Engineering$47,009
U54 · FY2019 · CA · contact PI
Core 2: Cell and Whole Animal Genome Engineering$13,828
U54 · FY2019 · CA · contact PI
Core 2: Cell and Whole Animal Genome Engineering$10,070
U54 · FY2019 · CA · contact PI
Center for Modeling Tumor Cell Migration Mechanics$1,868,789
U54 · FY2018 · CA
Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance$496,936
R01 · FY2018 · NS · contact PI
Center for Modeling Tumor Cell Migration Mechanics$99,786
U54 · FY2018 · CA
Center for Modeling Tumor Cell Migration Mechanics$72,666
U54 · FY2018 · CA
Core 2: Cell and Whole Animal Genome Engineering$49,263
U54 · FY2018 · CA · contact PI
Center for Modeling Tumor Cell Migration Mechanics$1,756,806
U54 · FY2017 · CA
Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance$491,889
R01 · FY2017 · NS · contact PI
Searching for Genetic Basis for Metastasis of Differentiated Thyroid Cancer$188,281
R21 · FY2017 · CA · contact PI
Core 2: Cell and Whole Animal Genome Engineering$62,538
U54 · FY2017 · CA · contact PI
Center for Modeling Tumor Cell Migration Mechanics$1,666,953
U54 · FY2016 · CA
Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance$486,944
R01 · FY2016 · NS · contact PI
Sleeping Beauty for uncovering cancer genes in mice$251,592
R01 · FY2016 · CA · contact PI
Immunotherapeutic targeting of the Glioblastoma Mutanome$200,100
R21 · FY2016 · CA
Center for Modeling Tumor Cell Migration Mechanics$190,106
U54 · FY2016 · CA
Searching for Genetic Basis for Metastasis of Differentiated Thyroid Cancer$166,243
R21 · FY2016 · CA · contact PI
Core 2: Cell and Whole Animal Genome Engineering$42,598
U54 · FY2016 · CA · contact PI
Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance$482,094
R01 · FY2015 · NS · contact PI
Sleeping Beauty for uncovering cancer genes in mice$251,795
R01 · FY2015 · CA · contact PI
Immunotherapeutic targeting of the Glioblastoma Mutanome$180,105
R21 · FY2015 · CA
Disordered Regulation of Wnt/beta-catenin Signaling in MPNST Development and Maintenance$490,339
R01 · FY2014 · NS · contact PI
A Genetic Screen for HCC Genes$293,831
R01 · FY2014 · CA · contact PI
Identifying and Targeting Pathways of Pancreatic Cancer Progression$261,150
P50 · FY2014 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$244,435
R01 · FY2014 · CA · contact PI
Discovery and Validation of Tumor Immunoevasion Mechanisms$176,610
R01 · FY2014 · CA · contact PI
Transposon-based screens for colorectal cancer genes$285,690
R01 · FY2013 · CA · contact PI
A Genetic Screen for HCC Genes$284,744
R01 · FY2013 · CA · contact PI
Identifying and Targeting Pathways of Pancreatic Cancer Progression$260,109
P50 · FY2013 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$237,060
R01 · FY2013 · CA · contact PI
Discovery and Validation of Tumor Immunoevasion Mechanisms$171,148
R01 · FY2013 · CA · contact PI
Mouse Genetics$115,165
P30 · FY2013 · CA · contact PI
Genetic Mechanisms of Cancer$69,349
P30 · FY2013 · CA · contact PI
Discovery and Validation of Tumor Immunoevasion Mechanisms$307,402
R01 · FY2012 · CA · contact PI
Transposon-based screens for colorectal cancer genes$303,925
R01 · FY2012 · CA · contact PI
A Genetic Screen for HCC Genes$302,919
R01 · FY2012 · CA · contact PI
Identifying and Targeting Pathways of Pancreatic Cancer Progression$282,664
P50 · FY2012 · CA · contact PI
Transposon-based Somatic Insertional Mutagenensis to Model NF-1$278,333
P50 · FY2012 · NS · contact PI
Sleeping Beauty for uncovering cancer genes in mice$252,382
R01 · FY2012 · CA · contact PI
Mouse Genetics$115,471
P30 · FY2012 · CA · contact PI
Genetic Mechanisms of Cancer$20,567
P30 · FY2012 · CA · contact PI
Mouse Genetics$2,678
P30 · FY2012 · CA · contact PI
Genetic Mechanisms of Cancer$2,678
P30 · FY2012 · CA · contact PI
Genetic Mechanisms of Cancer$1,776
P30 · FY2012 · CA · contact PI
Mouse Genetics$1,775
P30 · FY2012 · CA · contact PI
Transposon-based screens for colorectal cancer genes$303,925
R01 · FY2011 · CA · contact PI
A Genetic Screen for HCC Genes$302,919
R01 · FY2011 · CA · contact PI
Transposon-based Somatic Insertional Mutagenensis to Model NF-1$300,874
P50 · FY2011 · NS · contact PI
Identifying and Targeting Pathways of Pancreatic Cancer Progression$264,587
P50 · FY2011 · CA · contact PI
Mouse Genetics$128,496
P30 · FY2011 · CA · contact PI
Genetic Mechanisms of Cancer$22,885
P30 · FY2011 · CA · contact PI
A Genetic Screen for HCC Genes$325,038
R01 · FY2010 · CA · contact PI
Transposon-based screens for colorectal cancer genes$313,325
R01 · FY2010 · CA · contact PI
Identifying and Targeting Pathways of Pancreatic Cancer Progression$303,746
P50 · FY2010 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$257,668
R01 · FY2010 · CA · contact PI
Transposon-based Somatic Insertional Mutagenensis to Model NF-1$181,805
P50 · FY2010 · NS · contact PI
Mouse Genetics$137,867
P30 · FY2010 · CA · contact PI
Maternal dietary folic acid and risk of medulloblastoma in a mouse model$75,500
R03 · FY2010 · CA
Genetic Mechanisms of Cancer$24,554
P30 · FY2010 · CA · contact PI
Transposon-based screens for colorectal cancer genes$313,325
R01 · FY2009 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$257,668
R01 · FY2009 · CA · contact PI
Transposon-based Somatic Insertional Mutagenensis to Model NF-1$168,394
P50 · FY2009 · NS · contact PI
Mouse Genetics$133,949
P30 · FY2009 · CA · contact PI
Maternal dietary folic acid and risk of medulloblastoma in a mouse model$75,500
R03 · FY2009 · CA
Genetic Mechanisms of Cancer$23,857
P30 · FY2009 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$257,668
R01 · FY2008 · CA · contact PI
Transposon-based Somatic Insertional Mutagenensis to Model NF-1$172,434
P50 · FY2008 · NS · contact PI
Sleeping Beauty for uncovering cancer genes in mice$257,668
R01 · FY2007 · CA · contact PI
Transposon-based somatic mutagenesis/prostate cancer genetics$181,456
R21 · FY2007 · CA · contact PI
Sleeping Beauty for uncovering cancer genes in mice$262,727
R01 · FY2006 · CA · contact PI
Transposon-based somatic mutagenesis/prostate cancer genetics$203,830
R21 · FY2006 · CA · contact PI
Transposon Mutagenesis Development and Drug Abuse$314,796
R01 · FY2005 · DA
Transposon Mutagenesis Development and Drug Abuse$316,251
R01 · FY2004 · DA
Transposon Mediated Insertional Mutagenesis in Mice$327,891
R01 · FY2003 · DA
COOPERATING GENETIC EVENTS IN MYELOID LEUKEMIA DEVELOPME$238,965
R01 · FY2002 · CA
NF1 GENE IN MYELOID LEUKEMIA AND CYTOKINE SIGNALING$100,566
R29 · FY2002 · CA
COOPERATING GENETIC EVENTS IN MYELOID LEUKEMIA DEVELOPME$232,008
R01 · FY2001 · CA
NF1 GENE IN MYELOID LEUKEMIA AND CYTOKINE SIGNALING$97,310
R29 · FY2001 · CA
COOPERATING GENETIC EVENTS IN MYELOID LEUKEMIA DEVELOPME$225,069
R01 · FY2000 · CA
NF1 GENE IN MYELOID LEUKEMIA AND CYTOKINE SIGNALING$94,634
R29 · FY2000 · CA