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James Douglas Engel

Northwestern University

$17,006,737
Attributed
$22,570,031
Total exposure
16
Grants
13
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.2M · FY200523
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23

Funding mix

By agency

NIH$33,815,882 · 18

By mechanism

P01$14,419,283 · 3
R01$8,916,544 · 5
U01$8,344,941 · 1
S10$1,200,483 · 1
R21$418,295 · 1
U2C$339,336 · 1

Most similar at Northwestern University

Same institution · by research overlap

Others in their field

Top investigators on “Gene Expression

Research focus

Gene ExpressionTranscription FactorHemoglobinopathiesGenetic TranscriptionGlobinCellsAdultRegulationChromatinSickle Cell AnemiaGenesResearch PersonnelHemoglobinMolecularLaboratory MouseRepressionFetalProgramsIn VitroGenetically Modified AnimalsArtificial ChromosomesErythroid Progenitor CellsIn VivoEpigenetic Process

Grant awards (58)

Targeting Enzymatic Regulation of Fetal Hemoglobin Repression$2,157,816
P01 · FY2023 · HL · contact PI
Identification of novel y-globin corepressors and advanced inhibitor development$470,869
P01 · FY2023 · HL · contact PI
Administrative Core$214,962
P01 · FY2023 · HL · contact PI
Targeting Enzymatic Regulation of Fetal Hemoglobin Repression$2,165,218
P01 · FY2022 · HL · contact PI
Identification of novel y-globin corepressors and advanced inhibitor development$471,562
P01 · FY2022 · HL · contact PI
University of Michigan Kidney, Urology and Hematology Research Training Network$339,336
U2C · FY2022 · DK
Administrative Core$215,656
P01 · FY2022 · HL · contact PI
Targeting Enzymatic Regulation of Fetal Hemoglobin Repression$2,174,057
P01 · FY2021 · HL · contact PI
Identification of novel y-globin corepressors and advanced inhibitor development$472,390
P01 · FY2021 · HL · contact PI
Administrative Core$216,483
P01 · FY2021 · HL · contact PI
Targeting Enzymatic Regulation of Fetal Hemoglobin Repression$2,189,662
P01 · FY2020 · HL · contact PI
Identification of novel y-globin corepressors and advanced inhibitor development$500,270
P01 · FY2020 · HL · contact PI
Administrative Core$217,625
P01 · FY2020 · HL · contact PI
Targeting Enzymatic Regulation of Fetal Hemoglobin Repression$2,219,762
P01 · FY2019 · HL · contact PI
Identification of novel y-globin corepressors and advanced inhibitor development$507,798
P01 · FY2019 · HL · contact PI
Administrative Core$225,153
P01 · FY2019 · HL · contact PI
The 21st Hemoglobin Switching Conference$27,000
R13 · FY2018 · TR · contact PI
Improving HbF induction by inhibiting epigenetic target enzymes$1,736,085
U01 · FY2017 · HL · contact PI
Improving HbF induction by inhibiting epigenetic target enzymes$1,736,085
U01 · FY2016 · HL · contact PI
GATA3 regulation in transcriptional networks during hematopoietic cell developmen$387,412
R01 · FY2016 · AI · contact PI
20th Hemoglobin Switching Conference$55,000
R13 · FY2016 · DK · contact PI
Improving HbF induction by inhibiting epigenetic target enzymes$1,713,169
U01 · FY2015 · HL · contact PI
GATA3 regulation in transcriptional networks during hematopoietic cell developmen$387,412
R01 · FY2015 · AI · contact PI
Improving HbF induction by inhibiting epigenetic target enzymes$1,707,550
U01 · FY2014 · HL · contact PI
GATA3 regulation in transcriptional networks during hematopoietic cell developmen$387,412
R01 · FY2014 · AI · contact PI
19th Hemoglobin Switching Conference$14,500
R13 · FY2014 · HL · contact PI
Improving HbF induction by inhibiting epigenetic target enzymes$1,452,052
U01 · FY2013 · HL · contact PI
GATA3 regulation in transcriptional networks during hematopoietic cell developmen$364,168
R01 · FY2013 · AI · contact PI
Inactivation of LSD1 as a possible treatment for sickle cell disease$185,045
R21 · FY2013 · HL · contact PI
GATA3 regulation in transcriptional networks during hematopoietic cell developmen$387,412
R01 · FY2012 · AI · contact PI
Inactivation of LSD1 as a possible treatment for sickle cell disease$233,250
R21 · FY2012 · HL · contact PI
The 18th Hemoglobin Switching Conference$20,000
R13 · FY2012 · DK · contact PI
Leica SPX5 2-photon laser-scanning confocal microscope system$1,200,483
S10 · FY2010 · RR · contact PI
Beta-globin Transcriptional Regulation$486,535
R01 · FY2009 · HL · contact PI
Beta-globin Transcriptional Regulation$408,040
R01 · FY2008 · HL · contact PI
The 16th Hemoglobin Switching Conference$50,500
R13 · FY2008 · DK · contact PI
Beta-globin Transcriptional Regulation$407,307
R01 · FY2007 · HL · contact PI
The 4th International Conference on GATA Factors and Human Disease$10,000
R13 · FY2007 · DK · contact PI
Beta-globin Transcriptional Regulation$411,471
R01 · FY2006 · HL · contact PI
DRED repression of embryonic/fetal globin gene transcription*$288,608
R01 · FY2005 · HL
GATA transcription factor function in development$330,750
R01 · FY2004 · GM
DRED repression of embryonic/fetal globin gene transcription*$288,828
R01 · FY2004 · HL
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$382,500
R01 · FY2003 · HL
GATA transcription factor function in development$330,750
R01 · FY2003 · GM
GENETICS AND DEVELOPMENT OF THE SMALL MAF GENES$304,922
R01 · FY2003 · CA
DRED repression of embryonic/fetal globin gene transcri*$288,200
R01 · FY2003 · HL
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$445,261
R01 · FY2002 · HL
GENETICS AND DEVELOPMENT OF THE SMALL MAF GENES$290,569
R01 · FY2002 · CA
GATA transcription factor function in development$289,000
R01 · FY2002 · GM
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$71,896
R01 · FY2002 · HL
GATA transcription factor function in development$41,750
R01 · FY2002 · GM
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$2
R01 · FY2002 · HL
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$367,500
R01 · FY2001 · HL
GATA transcription factor function in development$330,750
R01 · FY2001 · GM
GENETICS AND DEVELOPMENT OF THE SMALL MAF GENES$283,922
R01 · FY2001 · CA
BETA-GLOBIN TRANSCRIPTIONAL REGULATION$367,500
R01 · FY2000 · HL
GATA TRANSCRIPTION FACTOR FUNCTION IN DEVELOPMENT$313,559
R01 · FY2000 · GM
GENETICS AND DEVELOPMENT OF THE SMALL MAF GENES$273,108
R01 · FY2000 · CA