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Jeffrey E Settleman

Massachusetts General Hospital

$9,528,639
Attributed
$10,851,496
Total exposure
8
Grants
5
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2M · FY200510
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10

Funding mix

By agency

NIH$10,851,496 · 8

By mechanism

R01$8,125,492 · 4
RC2$1,984,285 · 1
P50$618,707 · 1
R03$120,012 · 1
R13$3,000 · 1

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Guanosinetriphosphatases

Research focus

GuanosinetriphosphatasesProtein Structure FunctionTissue /Cell CultureBiological Signal TransductionEnzyme ActivityPharmaceutical PreparationsPhosphorylationPhosphotransferasesDrosophilidaeLaboratory MouseInsightBiochemicalOncogenicPathway InteractionsBaseCellsSignal TransductionProteinsMutationResponseTumorCancer Cell LineOncogenesGuanosinetriphosphatase Activating Protein

Grant awards (29)

Mechanistic Signatures of Drug Responses in Cancer$984,353
RC2 · FY2010 · HG
Mechanistic Signatures of Drug Responses in Cancer$999,932
RC2 · FY2009 · HG
Gefitinib-sensitive EGF receptor mutants in lung cancer$643,108
R01 · FY2009 · CA · contact PI
Targeting erlotinib-resistant lung cancer with rational combination treatments$340,249
P50 · FY2009 · CA · contact PI
Gefitinib-sensitive EGF receptor mutants in lung cancer$624,020
R01 · FY2008 · CA · contact PI
Specific Biochemical Inactivation of Oncogenic Ras$303,229
R01 · FY2008 · CA · contact PI
Targeting erlotinib-resistant lung cancer with rational combination treatments$278,458
P50 · FY2008 · CA · contact PI
Gefitinib-sensitive EGF receptor mutants in lung cancer$622,316
R01 · FY2007 · CA · contact PI
Specific Biochemical Inactivation of Oncogenic Ras$303,229
R01 · FY2007 · CA · contact PI
Gefitinib-sensitive EGF receptor mutants in lung cancer$536,728
R01 · FY2006 · CA · contact PI
Regulation and Functin of the p190 RhoGAPs$354,904
R01 · FY2006 · CA · contact PI
Specific Biochemical Inactivation of Oncogenic Ras$312,285
R01 · FY2006 · CA · contact PI
Regulation of p190 RhoGAP activity by phospholipids$39,372
R03 · FY2006 · TW · contact PI
Gefitinib-sensitive EGF receptor mutants in lung cancer$552,711
R01 · FY2005 · CA
Regulation and Functin of the p190 RhoGAPs$363,445
R01 · FY2005 · CA
Specific Biochemical Inactivation of Oncogenic Ras$319,800
R01 · FY2005 · CA
Regulation of p190 RhoGAP activity by phospholipids$40,320
R03 · FY2005 · TW
Regulation and Functin of the p190 RhoGAPs$363,445
R01 · FY2004 · CA
Specific Biochemical Inactivation of Oncogenic Ras$318,898
R01 · FY2004 · CA
Regulation of p190 RhoGAP activity by phospholipids$40,320
R03 · FY2004 · TW
FASEB Summer Research Conference on Small G-Proteins$3,000
R13 · FY2004 · CA
Regulation and Functin of the p190 RhoGAPs$363,445
R01 · FY2003 · CA
RHO GTPASE SIGNALING IN EMBRYO MORPHOGENESIS$304,143
R01 · FY2003 · GM
Regulation and Functin of the p190 RhoGAPs$363,445
R01 · FY2002 · CA
RHO GTPASE SIGNALING IN EMBRYO MORPHOGENESIS$295,285
R01 · FY2002 · GM
INTERACTION OF RAS AND RHO SIGNAL TRANSDUCTION PATHWAYS$368,262
R01 · FY2001 · CA
RHO GTPASE SIGNALING IN EMBRYO MORPHOGENESIS$286,683
R01 · FY2001 · GM
INTERACTION OF RAS AND RHO SIGNAL TRANSDUCTION PATHWAYS$357,536
R01 · FY2000 · CA
RHO GTPASE SIGNALING IN EMBRYO MORPHOGENESIS$168,575
R01 · FY2000 · GM