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David M Sabatini

Whitehead Institute For Biomedical Res

$25,995,600
Attributed
$25,995,600
Total exposure
12
Grants
12
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $2.1M · FY200520
$2.5M$1.9M$1.3M$625K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20

Funding mix

By agency

NIH$25,995,600 · 12

By mechanism

R01$19,264,429 · 5
R37$4,826,543 · 1
P50$690,247 · 2
R21$522,844 · 1
UH3$445,501 · 1
UH2$149,998 · 1

Top collaborators

No co-investigators on record.

Most similar at Whitehead Institute For Biomedical Res

Same institution · by research overlap

Others in their field

Top investigators on “Malignant Neoplasms

Research focus

Malignant NeoplasmsCellsResponsePathway InteractionsGrowthComplexProtein KinaseProteinsSirolimusSignal TransductionNutrientDiabetes MellitusIn VivoOrganismGrowth FactorMolecularStressMouse ModelHuman DiseaseInsightMammalsMediatingGenesMolecular Biology

Grant awards (71)

Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R01 · FY2020 · AI · contact PI
Cell Growth Signaling in Cancer Development$463,125
R01 · FY2020 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$416,813
R01 · FY2020 · CA · contact PI
Exploiting mitochondrial heteroplasmy for cancer chemotherapy$390,000
R01 · FY2020 · CA · contact PI
Impact of aging on intestinal tumorigenesis$150,000
UH3 · FY2020 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2019 · AI · contact PI
Cell Growth Signaling in Cancer Development$449,231
R01 · FY2019 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$416,813
R01 · FY2019 · CA · contact PI
Exploiting mitochondrial heteroplasmy for cancer chemotherapy$378,300
R01 · FY2019 · CA · contact PI
HDM2 as a Therapeutic Target in RCC$265,751
P50 · FY2019 · CA · contact PI
Impact of aging on intestinal tumorigenesis$145,501
UH3 · FY2019 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2018 · AI · contact PI
Cell Growth Signaling in Cancer Development$463,125
R01 · FY2018 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$394,875
R01 · FY2018 · CA · contact PI
Exploiting mitochondrial heteroplasmy for cancer chemotherapy$390,000
R01 · FY2018 · CA · contact PI
Trageting mTOR Dependent Mechanism in Clear Cell Renal Carcinoma$212,463
P50 · FY2018 · CA · contact PI
Impact of aging on intestinal tumorigenesis$150,000
UH3 · FY2018 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2017 · AI · contact PI
Cell Growth Signaling in Cancer Development$402,576
R01 · FY2017 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$394,875
R01 · FY2017 · CA · contact PI
Exploiting mitochondrial heteroplasmy for cancer chemotherapy$390,000
R01 · FY2017 · CA · contact PI
Trageting mTOR Dependent Mechanism in Clear Cell Renal Carcinoma$212,033
P50 · FY2017 · CA · contact PI
Impact of aging on intestinal tumorigenesis$74,999
UH2 · FY2017 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2016 · AI · contact PI
Cell Growth Signaling in Cancer Development$402,576
R01 · FY2016 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$394,875
R01 · FY2016 · CA · contact PI
Impact of aging on intestinal tumorigenesis$74,999
UH2 · FY2016 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2015 · AI · contact PI
Cell Growth Signaling in Cancer Development$402,576
R01 · FY2015 · CA · contact PI
Regulation of the mTOR Pathway by Nutrients$394,875
R01 · FY2015 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$482,625
R37 · FY2014 · AI · contact PI
Regulation of the mTOR Pathway by Nutrients$394,875
R01 · FY2014 · CA · contact PI
Cell Growth Signaling in Cancer Development$390,499
R01 · FY2014 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$453,668
R37 · FY2013 · AI · contact PI
Cell Growth Signaling in Cancer Development$402,576
R01 · FY2013 · CA · contact PI
Regulation of the mTOR Pathway By Nutrients$355,974
R01 · FY2013 · CA · contact PI
Elucidating a mechanism of mTORC1 activation independent of amino acids signaling$230,344
R21 · FY2013 · AG · contact PI
Inhibitors of serine biosynthesis$47,288
R03 · FY2013 · DA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$482,625
R37 · FY2012 · AI · contact PI
Cell Growth Signaling in Cancer Development$402,576
R01 · FY2012 · CA · contact PI
Regulation of the mTOR Pathway By Nutrients$378,696
R01 · FY2012 · CA · contact PI
Elucidating a mechanism of mTORC1 activation independent of amino acids signaling$292,500
R21 · FY2012 · AG · contact PI
Inhibitors of serine biosynthesis$48,750
R03 · FY2012 · DA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$482,625
R37 · FY2011 · AI · contact PI
Cell Growth Signaling in Cancer Development$410,787
R01 · FY2011 · CA · contact PI
Regulation of the mTOR Pathway By Nutrients$378,696
R01 · FY2011 · CA · contact PI
Novel Components of the mTORC1 and mTORC2 Pathways$487,500
R37 · FY2010 · AI · contact PI
Cell Growth Signaling in Cancer Development$423,772
R01 · FY2010 · CA · contact PI
Regulation of the mTOR Pathway By Nutrients$390,408
R01 · FY2010 · CA · contact PI
Rapamycin-Insensitive Signaling by Rictor-mTOR$453,455
R01 · FY2009 · AI · contact PI
Cell Growth Signaling in Cancer Development$406,715
R01 · FY2009 · CA · contact PI
Regulation of the mTOR Pathway By Nutrients$390,408
R01 · FY2009 · CA · contact PI
Rapamycin-Insensitive Signaling by Rictor-mTOR$453,455
R01 · FY2008 · AI · contact PI
Cell Growth Signaling in Cancer Development$399,870
R01 · FY2008 · CA · contact PI
Regulation of the mTOR growth pathway by nutrients$369,317
R01 · FY2008 · CA · contact PI
Metabolism and Phosphatase Regulation of the TOR Pathway$323,567
R01 · FY2008 · GM · contact PI
Rapamycin-Insensitive Signaling by Rictor-mTOR$462,238
R01 · FY2007 · AI · contact PI
Regulation of the mTOR growth pathway by nutrients$369,317
R01 · FY2007 · CA · contact PI
Metabolism and Phosphatase Regulation of the TOR Pathway$323,567
R01 · FY2007 · GM · contact PI
Rapamycin-Insensitive Signaling by Rictor-mTOR$476,044
R01 · FY2006 · AI · contact PI
Regulation of the mTOR growth pathway by nutrients$380,347
R01 · FY2006 · CA · contact PI
Metabolism and Phosphatase Regulation of the TOR Pathway$316,997
R01 · FY2006 · GM · contact PI
Rapamycin-Insensitive Signaling by Rictor-mTOR$449,500
R01 · FY2005 · AI
Regulation of the mTOR growth pathway by nutrients$389,500
R01 · FY2005 · CA
Metabolism and Phosphatase Regulation of the TOR Pathway$314,650
R01 · FY2005 · GM
TRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALING$427,500
R01 · FY2004 · AI
Regulation of the mTOR growth pathway by nutrients$371,050
R01 · FY2004 · CA
TRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALING$412,188
R01 · FY2003 · AI
TRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALING$271,250
R01 · FY2002 · AI
TRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALING$271,250
R01 · FY2001 · AI
TRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALING$271,250
R01 · FY2000 · AI