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Cheng Zhu

Georgia Institute Of Technology

$26,173,441
Attributed
$35,800,587
Total exposure
24
Grants
16
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.1M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$35,800,587 · 24

By mechanism

R01$25,326,476 · 9
U01$8,992,966 · 3
R56$539,518 · 2
R21$498,708 · 2
R03$439,357 · 3
P41$3,562 · 5

Top collaborators

Most similar at Georgia Institute Of Technology

Same institution · by research overlap

Others in their field

Top investigators on “Signal Transduction

Research focus

Signal TransductionMolecularCellsLigandsRegulationBaseKineticsMechanicsMediatingAffinityResponseReceptorSingle MoleculeBindingMolecular DynamicsMolecular ConformationInsightLigand BindingAdhesionsIn VivoAntigensBlood VesselsStructureT-Cell Receptor

Grant awards (100)

Optimizing TCR-CD3 signaling for immunotherapy of cancer$634,208
R01 · FY2025 · CA
Dysregulated mechanoimmunology of epigenetics-driven lymphomas$518,073
U01 · FY2025 · CA
Optimizing TCR-CD3 signaling for immunotherapy of cancer$652,880
R01 · FY2024 · CA
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$610,178
R01 · FY2024 · CA
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$600,878
U01 · FY2024 · CA · contact PI
Dysregulated mechanoimmunology of epigenetics-driven lymphomas$492,169
U01 · FY2024 · CA
Mechanotransduction of platelet receptors GPIb and GPIIb-IIIa$478,400
R01 · FY2024 · HL · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$80,627
U01 · FY2024 · CA · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$616,381
U01 · FY2023 · CA · contact PI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$557,231
R01 · FY2023 · CA
Dysregulated mechanoimmunology of epigenetics-driven lymphomas$532,624
U01 · FY2023 · CA
Mechanotransduction of platelet receptors GPIb and GPIIb-IIIa$494,755
R01 · FY2023 · HL · contact PI
Bispecific molecules linking T cell receptor and tumor antigen for cancer immunotherapy$79,874
U01 · FY2023 · CA · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$78,992
U01 · FY2023 · CA · contact PI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$629,441
R01 · FY2022 · CA
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$623,860
U01 · FY2022 · CA · contact PI
Mechanotransduction of platelet receptors GPIb and GPIIb-IIIa$501,154
R01 · FY2022 · HL · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$78,990
U01 · FY2022 · CA · contact PI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$72,215
R01 · FY2022 · CA
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$670,428
R01 · FY2021 · CA
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$643,620
U01 · FY2021 · CA · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$640,183
U01 · FY2021 · CA · contact PI
Mechanotransduction of platelet receptors GPIb and GPIIb-IIIa$521,918
R01 · FY2021 · HL · contact PI
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$75,971
U01 · FY2021 · CA · contact PI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$57,464
R01 · FY2021 · CA
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$946,295
U01 · FY2020 · CA · contact PI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$704,403
R01 · FY2020 · CA
Exploiting the Mechanobiology of PD-1 for Cancer Immunotherapy$656,845
U01 · FY2020 · CA · contact PI
T cell compartmentalization and antiviral response$624,373
R01 · FY2020 · AI
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade$169,500
R01 · FY2020 · CA
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$625,074
U01 · FY2019 · CA · contact PI
T cell compartmentalization and antiviral response$624,373
R01 · FY2019 · AI
Single-platelet analysis of mechano-reception by GPIb alpha$416,168
R01 · FY2019 · HL · contact PI
DNA origami based molecular probes for quantitative study on TCR/CD8 binding with pMHCs$187,393
R21 · FY2019 · AI
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$53,699
U01 · FY2019 · CA · contact PI
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$811,389
U01 · FY2018 · CA · contact PI
T cell compartmentalization and antiviral response$624,373
R01 · FY2018 · AI
Single-platelet analysis of mechano-reception by GPIb alpha$429,826
R01 · FY2018 · HL · contact PI
DNA origami based molecular probes for quantitative study on TCR/CD8 binding with pMHCs$240,797
R21 · FY2018 · AI
Divesity Supplement Mechanisms of impaired T-cell mechanosensing of melanoma Antigens$57,138
U01 · FY2018 · CA · contact PI
Mechanisms of impaired T-cell mechanosensing of melanoma antigens$780,284
U01 · FY2017 · CA · contact PI
T cell compartmentalization and antiviral response$692,917
R01 · FY2017 · AI
Single-platelet analysis of mechano-reception by GPIb alpha$449,022
R01 · FY2017 · HL · contact PI
T cell compartmentalization and antiviral response$641,320
R01 · FY2016 · AI
Visualizing Single Integrin Conformational Changes on Living Cells$502,511
R01 · FY2016 · AI · contact PI
Single-platelet analysis of mechano-reception by GPIb alpha$477,812
R01 · FY2016 · HL · contact PI
Visualizing Single Integrin Conformational Changes on Living Cells$454,493
R01 · FY2015 · AI · contact PI
Visualizing Single Integrin Conformational Changes on Living Cells$36,353
R01 · FY2015 · AI · contact PI
Mechanical Regulation of Selectin-Ligand Binding Kinetics$490,211
R01 · FY2014 · AI · contact PI
Visualizing Single Integrin Conformational Changes on Living Cells$454,493
R01 · FY2014 · AI · contact PI
Mechanical Regulation of Selectin-Ligand Binding Kinetics$460,797
R01 · FY2013 · AI · contact PI
Visualizing Single Integrin Conformational Changes on Living Cells$427,224
R01 · FY2013 · AI · contact PI
Structural bases of ADAMTS-13 and VWF A2 interactions$53,384
R03 · FY2013 · TW · contact PI
Mechanical Regulation of Selectin-Ligand Binding Kinetics$564,467
R01 · FY2012 · AI · contact PI
Visualizing Single Integrin Conformational Changes on Living Cells$480,804
R01 · FY2012 · AI · contact PI
Kinetic analysis of ligand binding by TCR and CD8$388,518
R56 · FY2012 · AI · contact PI
Mechanical Regulation of Binding and Cleavage of VWF by ADAMTS-13$367,660
R01 · FY2012 · HL · contact PI
Biophysical Analysis of GPIb-VWF Interaction$364,564
R01 · FY2012 · HL · contact PI
Structural bases of ADAMTS-13 and VWF A2 interactions$55,564
R03 · FY2012 · TW · contact PI
Mechanical Regulation of Selectin-Ligand Binding Kinetics$531,991
R01 · FY2011 · AI · contact PI
Mechanical Regulation of Binding and Cleavage of VWF by ADAMTS-13$371,374
R01 · FY2011 · HL · contact PI
Biophysical Analysis of GPIb-VWF Interaction$368,247
R01 · FY2011 · HL · contact PI
Structural bases of ADAMTS-13 and VWF A2 interactions$67,254
R03 · FY2011 · TW · contact PI
STRUCTURAL MECHANISM OF INTEGRIN ACTIVATIN INDUCED BY TALIN$1,036
P41 · FY2011 · RR · contact PI
Mechanical Regulation of Selectin-Ligand Binding Kinetics$501,872
R01 · FY2010 · AI · contact PI
Mechanical Regulation of Binding and Cleavage of VWF by ADAMTS-13$371,374
R01 · FY2010 · HL · contact PI
Biophysical Analysis of GPIb-VWF Interaction$368,247
R01 · FY2010 · HL · contact PI
Mechanical Regulation of Binding and Cleavage of VWF by ADAMTS-13$384,124
R01 · FY2009 · HL · contact PI
Kinetic Mechanical Properties of aLb2 Integrin$368,852
R01 · FY2009 · AI · contact PI
Biophysical Analysis of GPIb-VWF Interaction$355,497
R01 · FY2009 · HL · contact PI
MOLECULAR SIMULATIONS OF INTEGRIN CONFORMATIONAL CHANGE$790
P41 · FY2009 · RR · contact PI
MD SIMULATIONS OF MECHANICAL REGULATION OF BIOMOLECULAR INTERACTIONS$790
P41 · FY2009 · RR · contact PI
Kinetic Mechanical Properties of aLb2 Integrin$393,557
R01 · FY2008 · AI · contact PI
Biophysical Analysis of GPIb-VWF Interaction$368,247
R01 · FY2008 · HL · contact PI
Mechanical regulation of selectin-ligand binding kinetics$151,000
R56 · FY2008 · AI · contact PI
Biophysical Analysis of Leukocyte Adhesion Under Flow$35,728
R03 · FY2008 · TW · contact PI
MD SIMULATIONS OF MECHANICAL REGULATION OF BIOMOLECULAR INTERACTIONS$473
P41 · FY2008 · RR · contact PI
MOLECULAR SIMULATIONS OF INTEGRIN CONFORMATIONAL CHANGE$473
P41 · FY2008 · RR · contact PI
Kinetic Mechanical Properties of aLb2 Integrin$389,462
R01 · FY2007 · AI · contact PI
Biophysical Analysis of Leukocyte Adhesion Under Flow$37,836
R03 · FY2007 · TW · contact PI
Kinetic Mechanical Properties of aLb2 Integrin$398,213
R01 · FY2006 · AI · contact PI
Biophysical Analysis of Leukocyte Adhesion Under Flow$46,685
R03 · FY2006 · TW · contact PI
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$409,501
R01 · FY2005 · AI
Kinetic Mechanical Properties of aLb2 Integrin$308,137
R01 · FY2005 · AI
Kinetic Mechanical Properties of aLb2 Integrin$22,153
R01 · FY2005 · AI
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$408,259
R01 · FY2004 · AI
KINETIC PROPERTIES OF SELECTINS$293,900
R01 · FY2004 · AI
Kinetic Analysis of the PSGL-1 Molecule$47,968
R03 · FY2004 · TW
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$407,055
R01 · FY2003 · AI
KINETIC PROPERTIES OF SELECTINS$324,655
R01 · FY2003 · AI
Kinetic Analysis of the PSGL-1 Molecule$47,968
R03 · FY2003 · TW
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$340,751
R01 · FY2002 · AI
KINETIC PROPERTIES OF SELECTINS$330,819
R01 · FY2002 · AI
Kinetic Analysis of the PSGL-1 Molecule$46,970
R03 · FY2002 · TW
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$18,946
R01 · FY2002 · AI
KINETIC PROPERTIES OF SELECTINS$6,154
R01 · FY2002 · AI
KINETIC PROPERTIES OF SELECTINS$343,900
R01 · FY2001 · AI
Ligand Binding Kinetics and Cell Adhesion by Fc Receptor$330,107
R01 · FY2001 · AI
KINETIC PROPERTIES OF SELECTINS$273,146
R01 · FY2000 · AI
KINETIC PROPERTIES OF SELECTINS$70,518
R21 · FY2000 · AI