← Leaderboards
Vern L. Schramm
Yeshiva University
$38,820,552
Attributed
$42,369,555
Total exposure
21
Grants
17
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $2.4M · FY2005–25$2.5M$1.9M$1.3M$625K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$42,369,555 · 21
By mechanism
R01$33,384,838 · 8
P01$4,885,362 · 3
R37$3,531,416 · 1
R41$225,000 · 1
P41$185,095 · 5
P30$150,344 · 2
Top collaborators
- Thomas Meek5 shared
- Peter Tyler5 shared
- Steven Isaacman1 shared
Others in their field
Top investigators on “Analog”
- David Heimbrook · Leidos Biomedical Research, Inc.$196,589,777
- Constance Ann Benson · University Of California, San Diego$84,289,569
- Norman Wolmark · Nsabp Foundation, Inc.$51,982,954
- Robert Turner Schooley · University Of Colorado Denver$48,513,949
- Kenneth A Bloom · University Of Nebraska-Lincoln$46,979,168
- John Hobbs · Suny At Stony Brook$41,239,084
Research focus
AnalogDesignEnzymesIsotopesStructureKineticsInhibitor/AntagonistProteinsBaseComplexPharmaceutical PreparationsReactionGenerationsElectrostaticsCatalytic DomainChemistryCatalysisLabelProgramsCellsPathway InteractionsMalignant NeoplasmsPurine-Nucleoside PhosphorylaseClinical Trials
Grant awards (106)
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins$668,741
R01 · FY2025 · AI · contact PI
Targeting the PNP - SAMHD1 synthetic-lethal combination in cancer$603,347
R01 · FY2025 · CA · contact PI
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins$668,741
R01 · FY2024 · AI · contact PI
Targeting the PNP - SAMHD1 synthetic-lethal combination in cancer$603,347
R01 · FY2024 · CA · contact PI
Chemical Synthesis Shared Resource$47,042
P30 · FY2024 · CA · contact PI
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins$668,741
R01 · FY2023 · AI · contact PI
Transition State Analysis of Enzymatic Reactions$588,000
R01 · FY2023 · GM · contact PI
Chemical Synthesis Shared Resource$49,310
P30 · FY2023 · CA · contact PI
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins$668,741
R01 · FY2022 · AI · contact PI
Transition State Analysis of Enzymatic Reactions$588,000
R01 · FY2022 · GM · contact PI
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE$1,003,662
R01 · FY2021 · AI
Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins$668,741
R01 · FY2021 · AI · contact PI
Transition State Analysis of Enzymatic Reactions$588,000
R01 · FY2021 · GM · contact PI
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE$1,020,767
R01 · FY2020 · AI
Transition State Analysis of Enzymatic Reactions$587,271
R01 · FY2020 · GM · contact PI
Experimental Therapeutics$26,996
P30 · FY2020 · CA · contact PI
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE$1,014,009
R01 · FY2019 · AI
Transition State Analysis of Enzymatic Reactions$576,150
R01 · FY2019 · GM · contact PI
Experimental Therapeutics$26,996
P30 · FY2019 · CA · contact PI
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE$1,032,586
R01 · FY2018 · AI
Transition State Analysis of Enzymatic Reactions$344,730
R01 · FY2018 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$332,772
P01 · FY2018 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$261,454
R01 · FY2018 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$231,420
R01 · FY2018 · GM · contact PI
Transition State Analysis of Enzymatic Reactions$116,253
R01 · FY2018 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$29,138
R01 · FY2018 · CA · contact PI
PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE$1,083,730
R01 · FY2017 · AI
Transition State Analysis of Enzymatic Reactions$576,150
R01 · FY2017 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$498,511
P01 · FY2017 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$290,592
R01 · FY2017 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$576,150
R01 · FY2016 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$507,962
P01 · FY2016 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$290,592
R01 · FY2016 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$547,454
R01 · FY2015 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$517,141
P01 · FY2015 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$340,783
P01 · FY2015 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$162,379
R01 · FY2015 · CA · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$128,213
R01 · FY2015 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$49,768
R01 · FY2015 · GM · contact PI
2015 Nucleosides, Nucleotides & Oligonucleotides Gordon Research Conference and Seminar$7,500
R13 · FY2015 · AI · contact PI
Transition State Analysis of Enzymatic Reactions$615,685
R01 · FY2014 · GM · contact PI
Dynamics in enzymatic catalysis and transition state analogue binding.$526,050
P01 · FY2014 · GM · contact PI
Methylthioadenosine Phosphorylase and AdoMet Synthetase in Cancer$268,912
R01 · FY2014 · CA · contact PI
Orally available transition state inhibitors for triple negative breast cancer$225,000
R41 · FY2014 · CA
Transition State Analysis of Enzymatic Reactions$686,855
R01 · FY2013 · GM · contact PI
Transition State Analysis of Enzymatic Reactions$628,305
R01 · FY2012 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$484,071
R01 · FY2012 · AI · contact PI
Transition State Analogues as Modulators of DNA Methylation$261,900
R01 · FY2012 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$85,726
R01 · FY2012 · GM · contact PI
Transition State Analysis of Enzymatic Reactions$653,028
R01 · FY2011 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$485,892
R01 · FY2011 · AI · contact PI
Ricin-Mechanism, Transition State and Inhibitor Design$366,196
R01 · FY2011 · CA · contact PI
Transition State Analogues as Modulators of DNA Methylation$261,900
R01 · FY2011 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$665,271
R01 · FY2010 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$490,845
R01 · FY2010 · AI · contact PI
Ricin-Mechanism, Transition State and Inhibitor Design$379,534
R01 · FY2010 · CA · contact PI
Transition State Analogues as Modulators of DNA Methylation$270,000
R01 · FY2010 · CA · contact PI
Transition State Analysis of Enzymatic Reactions$658,125
R01 · FY2009 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$482,185
R01 · FY2009 · AI · contact PI
Ricin-Mechanism, Transition State and Inhibitor Design$374,122
R01 · FY2009 · CA · contact PI
Transition State Analogues as Modulators of DNA Methylation$270,000
R01 · FY2009 · CA · contact PI
PURINES & PURINE ANTIMETABOLITES IN MALARIA$26,659
P41 · FY2009 · RR · contact PI
Transition State Analysis of Enzymatic Reactions$623,731
R01 · FY2008 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$510,862
R01 · FY2008 · AI · contact PI
Ricin-Mechanism, Transition State and Inhibitor Design$365,254
R01 · FY2008 · CA · contact PI
Chemistry Core$358,123
P01 · FY2008 · GM · contact PI
Transition State Analogues as Modulators of DNA Methylation$270,000
R01 · FY2008 · CA · contact PI
Coordination of Protein Dynamics and Chemistry in PNP$210,855
P01 · FY2008 · GM · contact PI
PURINES & PURINE ANTIMETABOLITES IN MALARIA$24,845
P41 · FY2008 · RR · contact PI
Transition State Analysis of Enzymatic Reactions$499,254
R37 · FY2007 · GM · contact PI
Ricin-Mechanism, Transition State and Inhibitor Design$400,341
R01 · FY2007 · CA · contact PI
Chemistry Core$359,146
P01 · FY2007 · GM · contact PI
Coordination of Protein Dynamics and Chemistry in PNP$211,972
P01 · FY2007 · GM · contact PI
PURINES & PURINE ANTIMETABOLITES IN MALARIA$24,036
P41 · FY2007 · RR · contact PI
Transition State Analysis of Enzymatic Reactions$501,372
R37 · FY2006 · GM · contact PI
Purine Pathways and Inhibitor Design in Plasmodium$489,912
R01 · FY2006 · AI · contact PI
Ricin Mechanism, Transition State and Inhibitor Design$368,435
R01 · FY2006 · CA · contact PI
Chemistry Core$219,353
P01 · FY2006 · GM · contact PI
Coordination of Protein Dynamics and Chemistry in PNP$130,022
P01 · FY2006 · GM · contact PI
PURINES & PURINE ANTIMETABOLITES IN MALARIA$26,444
P41 · FY2006 · RR · contact PI
Transition State Analysis of Enzymatic Reactions$500,719
R37 · FY2005 · GM
Purine Pathways and Inhibitor Design in Plasmodium$487,380
R01 · FY2005 · AI
Ricin Mechanism, Transition State and Inhibitor Design$366,309
R01 · FY2005 · CA
Chemistry Core$212,964
P01 · FY2005 · GM
Coordination of Protein Dynamics and Chemistry in PNP$126,958
P01 · FY2005 · GM
PURINES &PURINE ANTIMETABOLITES IN MALARIA$32,470
P41 · FY2005 · RR
Transition State Analysis of Enzymatic Reactions$488,369
R37 · FY2004 · GM
Purine Pathways and Inhibitor Design in Plasmodium$473,477
R01 · FY2004 · AI
Ricin Mechanism, Transition State and Inhibitor Design$355,642
R01 · FY2004 · CA
Chemistry Core$209,261
P01 · FY2004 · GM
Coordination of Protein Dynamics and Chemistry in PNP$123,489
P01 · FY2004 · GM
PURINES &PURINE ANTIMETABOLITES IN MALARIA$50,641
P41 · FY2004 · RR
Transition State Analysis of Enzymatic Reactions$484,379
R37 · FY2003 · GM
Purine Pathways and Inhibitor Design in Plasmodium$474,978
R01 · FY2003 · AI
PERTUSSIS, DIPHTHERIA, CHOLERA TOXINS-INHIBITOR DESIGN$440,568
R01 · FY2003 · AI
Ricin Mechanism, Transition State and Inhibitor Design$345,283
R01 · FY2003 · CA
Purine Pathways and Inhibitor Design in Plasmodium$448,511
R01 · FY2002 · AI
PERTUSSIS, DIPHTHERIA, CHOLERA TOXINS-INHIBITOR DESIGN$427,735
R01 · FY2002 · AI
Ricin Mechanism, Transition State and Inhibitor Design$377,582
R01 · FY2002 · CA
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONS$361,299
R37 · FY2002 · GM
PERTUSSIS, DIPHTHERIA, CHOLERA TOXINS-INHIBITOR DESIGN$415,278
R01 · FY2001 · AI
RICIN--MECHANISM, TRANSITION STATE AND INHIBITOR DESIGN$362,050
R01 · FY2001 · CA
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONS$352,355
R37 · FY2001 · GM
PERTUSSIS, DIPHTHERIA, CHOLERA TOXINS-INHIBITOR DESIGN$403,182
R01 · FY2000 · AI
RICIN--MECHANISM, TRANSITION STATE AND INHIBITOR DESIGN$352,909
R01 · FY2000 · CA
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONS$343,669
R37 · FY2000 · GM