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Bruce A Mc Clane

University Of Pittsburgh At Pittsburgh

$13,048,720
Attributed
$15,434,126
Total exposure
8
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.1M · FY200524
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24

Funding mix

By agency

NIH$15,434,126 · 8

By mechanism

R01$9,239,551 · 2
R37$3,021,382 · 1
R21$1,719,388 · 4
U54$1,453,805 · 1

Top collaborators

Most similar at University Of Pittsburgh At Pittsburgh

Same institution · by research overlap

Others in their field

Top investigators on “Clostridium Perfringens

Research focus

Clostridium PerfringensToxinVirulenceIn VivoMediatingProductionEnterotoxinsReceptorIntestinesMutantInfectionCellsMolecularIn VitroComplexFoodborne IllnessBaseReceptor BindingBacteriaFood PoisoningPlasmidsClostridium Perfringens EnterotoxinProteinsMutagenesis

Grant awards (48)

Mechanism of action of C. perfringens enterotoxin$475,799
R01 · FY2024 · AI · contact PI
Evaluating the role of branched chain amino acid transporters in Clostridium perfringens-induced gas gangrene in diabetic and normal mouse models$222,000
R21 · FY2024 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$475,799
R01 · FY2023 · AI · contact PI
Evaluating the role of branched chain amino acid transporters in Clostridium perfringens-induced gas gangrene in diabetic and normal mouse models$205,250
R21 · FY2023 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$474,299
R01 · FY2022 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$469,800
R01 · FY2021 · AI · contact PI
NanI sialidase: Effects on Clostridium perfringens enterotoxin activity and contributions to C. perfringens type F infection$235,125
R21 · FY2021 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$483,925
R01 · FY2020 · AI · contact PI
NanI sialidase: Effects on Clostridium perfringens enterotoxin activity and contributions to C. perfringens type F infection$210,063
R21 · FY2020 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$385,859
R01 · FY2019 · AI · contact PI
Evaluating the Clostridium perfringens Agr-like Quorum Sensing System as a Therapeutic Target$235,113
R21 · FY2019 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$385,859
R01 · FY2018 · AI · contact PI
Evaluating the Clostridium perfringens Agr-like Quorum Sensing System as a Therapeutic Target$209,970
R21 · FY2018 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$385,859
R01 · FY2017 · AI · contact PI
Pathogenic Contributions of Clostridium perfringens NanI Sialidase$212,107
R21 · FY2017 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$385,800
R01 · FY2016 · AI · contact PI
Pathogenic Contributions of Clostridium perfringens NanI Sialidase$189,760
R21 · FY2016 · AI · contact PI
Mechanism of action of C. perfringens enterotoxin$399,009
R01 · FY2015 · AI · contact PI
Mechanisms of Action of C. Perfringens Enterotoxin$332,966
R37 · FY2014 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$397,821
R01 · FY2013 · AI · contact PI
Mechanisms of Action of C. Perfringens Enterotoxin$312,841
R37 · FY2013 · AI · contact PI
Early interaction between clostridium perfringens epsilon toxin and host cells$232,179
U54 · FY2013 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$417,751
R01 · FY2012 · AI · contact PI
Mechanisms of Action of C. Perfringens Enterotoxin$332,808
R37 · FY2012 · AI · contact PI
Early interaction between clostridium perfringens epsilon toxin and host cells$268,306
U54 · FY2012 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$416,537
R01 · FY2011 · AI · contact PI
Mechanisms of Action of C. Perfringens Enterotoxin$332,722
R37 · FY2011 · AI · contact PI
Early interaction between clostridium perfringens epsilon toxin and host cells$318,204
U54 · FY2011 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$415,430
R01 · FY2010 · AI · contact PI
Mechanisms of Action of C. Perfringens Enterotoxin$348,940
R37 · FY2010 · AI · contact PI
Early interaction between clostridium perfringens epsilon toxin and host cells$323,720
U54 · FY2010 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$433,750
R01 · FY2009 · AI · contact PI
Early interaction between clostridium perfringens epsilon toxin and host cells$311,396
U54 · FY2009 · AI · contact PI
Mechanisms of Action of C. perfringens Enterotoxin$271,046
R37 · FY2009 · AI · contact PI
Mechanisms of Action of C. perfringens Enterotoxin$259,985
R37 · FY2008 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$336,973
R01 · FY2007 · AI · contact PI
Mechanisms of Action of C. perfringens Enterotoxin$265,170
R37 · FY2007 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$402,385
R01 · FY2006 · AI · contact PI
Mechanisms of Action of C. perfringens Enterotoxin$273,240
R37 · FY2006 · AI · contact PI
Clostridium perfringens Type B-D Virulence Plasmids$400,692
R01 · FY2005 · AI
Mechanisms of Action of C. perfringens Enterotoxin$291,664
R37 · FY2005 · AI
Clostridium perfringens Type B-D Virulence Plasmids$404,230
R01 · FY2004 · AI
MECAHNISMS OF ACTION OF C PERFRINGENS EXTEROTOXIN$219,929
R01 · FY2004 · AI
MECHANISMS OF ACTION OF C PERFRINGENS EXTEROTOXIN$220,055
R01 · FY2003 · AI
Clostridium perfringens Type B-D Virulence Plasmids$189,506
R01 · FY2003 · AI
MECAHNISMS OF ACTION OF C PERFRINGENS EXTEROTOXIN$220,355
R01 · FY2002 · AI
MECAHNISMS OF ACTION OF C PERFRINGENS EXTEROTOXIN$221,006
R01 · FY2001 · AI
MECAHNISMS OF ACTION OF C PERFRINGENS EXTEROTOXIN$221,123
R01 · FY2000 · AI