← Leaderboards
Jie Shen
Brigham And Women'S Hospital
$46,115,873
Attributed
$47,923,973
Total exposure
15
Grants
15
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $8.1M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$55,026,103 · 16
By mechanism
R01$28,321,965 · 6
P50$14,205,700 · 5
RF1$6,603,620 · 2
R37$4,530,086 · 1
RC2$1,347,232 · 1
R13$17,500 · 1
Top collaborators
- Norbert Perrimon5 shared
Others in their field
Top investigators on “Pathogenesis”
- Jeffrey P Krischer · University Of South Florida$473,867,135
- Constance Ann Benson · University Of California, San Diego$309,631,408
- Daniel R Kuritzkes · Brigham And Women'S Hospital$212,627,101
- Richard K. Wilson · Washington University$203,917,615
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$198,007,440
- Carol Nesel · Westat$147,274,423
Research focus
PathogenesisNeuronsMolecularMutationGenesGeneticPathway InteractionsProteinsAge RelatedGenerationsImpairmentMediatingAffectKnockout MiceNerve DegenerationExhibitsInsightNeurodegenerative DisordersDefectBrainAlpha SynucleinLinkPhysiologicalParkinson Disease
Grant awards (112)
Presenilin and APP in the Brain$828,365
R01 · FY2025 · NS · contact PI
Presenilin and APP in the Brain$828,365
R01 · FY2024 · NS · contact PI
Presenilin and APP in the Brain$2,675,675
RF1 · FY2021 · NS · contact PI
Identification of Presinilin downstream targets in neuronal survival$735,686
R01 · FY2021 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$670,490
R37 · FY2021 · NS · contact PI
Identification of Presinilin downstream targets in neuronal survival$734,120
R01 · FY2020 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$670,490
R37 · FY2020 · NS · contact PI
Presenilins in the hippocampal network and Alzheimer's disease$651,134
R01 · FY2020 · NS · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,500
P50 · FY2020 · NS · contact PI
Development of novel therapies for FAD$3,927,945
RF1 · FY2019 · AG · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,402,795
P50 · FY2019 · NS · contact PI
Identification of Presinilin downstream targets in neuronal survival$734,120
R01 · FY2019 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$670,490
R37 · FY2019 · NS · contact PI
Presenilins in the hippocampal network and Alzheimer's disease$651,134
R01 · FY2019 · NS · contact PI
Genetic interaction of LRRK2 and alpha-synuclein$344,128
P50 · FY2019 · NS · contact PI
Administrative Core$219,032
P50 · FY2019 · NS · contact PI
Mouse Core$131,538
P50 · FY2019 · NS · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,402,795
P50 · FY2018 · NS · contact PI
Identification of Presinilin downstream targets in neuronal survival$734,120
R01 · FY2018 · NS · contact PI
Presenilins in the hippocampal network and Alzheimer's disease$651,134
R01 · FY2018 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$629,818
R37 · FY2018 · NS · contact PI
Genetic interaction of LRRK2 and alpha-synuclein$344,128
P50 · FY2018 · NS · contact PI
Administrative Core$219,032
P50 · FY2018 · NS · contact PI
Mouse Core$131,538
P50 · FY2018 · NS · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,402,794
P50 · FY2017 · NS · contact PI
Identification of Presinilin downstream targets in neuronal survival$678,155
R01 · FY2017 · NS · contact PI
Presenilins in the hippocampal network and Alzheimer's disease$651,134
R01 · FY2017 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$629,818
R37 · FY2017 · NS · contact PI
APP/APLP1/APLP2 in the brain$446,234
R01 · FY2017 · NS · contact PI
Genetic interaction of LRRK2 and alpha-synuclein$344,126
P50 · FY2017 · NS · contact PI
Administrative Core$219,034
P50 · FY2017 · NS · contact PI
Mouse Core$131,538
P50 · FY2017 · NS · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,417,153
P50 · FY2016 · NS · contact PI
Presenilins in the hippocampal network and Alzheimer's disease$651,134
R01 · FY2016 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$629,818
R37 · FY2016 · NS · contact PI
APP/APLP1/APLP2 in the brain$446,234
R01 · FY2016 · NS · contact PI
Genetic interaction of LRRK2 and alpha-synuclein$344,128
P50 · FY2016 · NS · contact PI
Administrative Core$219,031
P50 · FY2016 · NS · contact PI
Mouse Core$145,897
P50 · FY2016 · NS · contact PI
alpha-Synuclein and LRRK2 in the Pathogenesis of Parkinson's Disease$1,475,093
P50 · FY2015 · NS · contact PI
LRRK in Autophagy Function and Dopaminergic Neuron Survival$629,162
R37 · FY2015 · NS · contact PI
APP/APLP1/APLP2 in the brain$446,234
R01 · FY2015 · NS · contact PI
Role of Presenilins in the Synapse$378,105
R01 · FY2015 · NS · contact PI
Genetic interaction of LRRK2 and alpha-synuclein$344,047
P50 · FY2015 · NS · contact PI
Administrative Core$238,350
P50 · FY2015 · NS · contact PI
Mouse Core$145,869
P50 · FY2015 · NS · contact PI
APP/APLP1/APLP2 in the brain$441,213
R01 · FY2014 · NS · contact PI
Role of Presenilins in the Synapse$373,305
R01 · FY2014 · NS · contact PI
PINK1 and Parkin in dopaminergic and mitochondrial functions$370,836
R01 · FY2014 · NS · contact PI
Function and Dysfunction of LRRK2$369,836
R01 · FY2014 · NS · contact PI
APP/APLP1/APLP2 in the brain$444,543
R01 · FY2013 · NS · contact PI
Role of Presenilins in the Synapse$361,392
R01 · FY2013 · NS · contact PI
Function and Dysfunction of LRRK2$360,497
R01 · FY2013 · NS · contact PI
PINK1 and Parkin in dopaminergic and mitochondrial functions$360,497
R01 · FY2013 · NS · contact PI
Function and Dysfunction of LRRK2$25,550
R01 · FY2013 · NS · contact PI
Role of Presenilins in the Synapse$374,499
R01 · FY2012 · NS · contact PI
PINK1 and Parkin in dopaminergic and mitochondrial functions$372,563
R01 · FY2012 · NS · contact PI
Function and Dysfunction of LRRK2$371,553
R01 · FY2012 · NS · contact PI
Presenilins, Gamma-Secretase and Notch in Neuronal Death$360,963
R01 · FY2012 · NS · contact PI
2012 Neurobiology of Brain Disorders GRC$17,500
R13 · FY2012 · NS · contact PI
Role of Presenilins in the Synapse$373,756
R01 · FY2011 · NS · contact PI
PINK1 and Parkin in dopaminergic and mitochondrial functions$371,134
R01 · FY2011 · NS · contact PI
Function and Dysfunction of LRRK2$370,128
R01 · FY2011 · NS · contact PI
Presenilins, Gamma-Secretase and Notch in Neuronal Death$360,963
R01 · FY2011 · NS · contact PI
Neurodegeneration and Synaptic Transmission in Aging$680,100
RC2 · FY2010 · AG · contact PI
PINK1 and Parkin in dopaminergic and mitochondrial functions$389,375
R01 · FY2010 · NS · contact PI
Function and Dysfunction of LRRK2$389,375
R01 · FY2010 · NS · contact PI
Presenilins, Gamma-Secretase and Notch in Neuronal Death$364,648
R01 · FY2010 · NS · contact PI
Presenilins in Synaptic Plasticity and Neurodegeneration$351,536
R01 · FY2010 · NS · contact PI
PINK1 and Recessive Parkinsonism$89,000
R01 · FY2010 · NS · contact PI
Neurodegeneration and Synaptic Transmission in Aging$667,132
RC2 · FY2009 · AG · contact PI
Development of Mouse Models of PD$543,008
P50 · FY2009 · NS · contact PI
Presenilins, Gamma-Secretase and Notch in Neuronal Death$368,330
R01 · FY2009 · NS · contact PI
DJ-1 in Dopaminergic Neuronal Function and Survival$365,488
R01 · FY2009 · NS · contact PI
Presenilins in Synaptic Plasticity and Neurodegeneration$355,087
R01 · FY2009 · NS · contact PI
PINK1 and Recessive Parkinsonism$354,116
R01 · FY2009 · NS · contact PI
PINK1 and Recessive Parkinsonism$177,917
R01 · FY2009 · NS · contact PI
Development of Mouse Models of PD$526,830
P50 · FY2008 · NS · contact PI
Presenilins, Gamma-Secretase and Notch in Neuronal Death$368,330
R01 · FY2008 · NS · contact PI
DJ-1 in Dopaminergic Neuronal Function and Survival$361,230
R01 · FY2008 · NS · contact PI
Presenilins in Synaptic Plasticity and Neurodegeneration$355,087
R01 · FY2008 · NS · contact PI
PINK1 and Recessive Parkinsonism$354,116
R01 · FY2008 · NS · contact PI
Development of Mouse Models of PD$485,943
P50 · FY2007 · NS · contact PI
DJ-1 in Dopaminergic Neuronal Function and Survival$357,095
R01 · FY2007 · NS · contact PI
Presenilins in Synaptic Plasticity and Neurodegeneration$355,087
R01 · FY2007 · NS · contact PI
PINK1 and Recessive Parkinsonism$354,116
R01 · FY2007 · NS · contact PI
Development of Mouse Models of PD$478,143
P50 · FY2006 · NS · contact PI
Presenilins in Synaptic Plasticity and Neurodegeneration$365,692
R01 · FY2006 · NS · contact PI
PINK1 and Recessive Parkinsonism$364,693
R01 · FY2006 · NS · contact PI
DJ-1 in Dopaminergic Neuronal Function and Survival$363,626
R01 · FY2006 · NS · contact PI
PS1 & PS2 in Cortical Development and Notch Signaling$328,592
R01 · FY2006 · NS · contact PI
Development of Mouse Models of PD$462,948
P50 · FY2005 · NS
PINK1 and Recessive Parkinsonism$373,153
R01 · FY2005 · NS
DJ-1 in Dopaminergic Neuronal Function and Survival$367,962
R01 · FY2005 · NS
PS1 &PS2 in Cortical Development and Notch Signaling$336,500
R01 · FY2005 · NS
Studies of Parkin KO Cells and Mice as PD Models$349,385
R01 · FY2004 · NS
PS-1 in APP Processing and Synaptic Function$349,385
R01 · FY2004 · NS
PS1 &PS2 in Cortical Development and Notch Signaling$336,500
R01 · FY2004 · NS
Studies of Parkin KO Cells and Mice as PD Models$349,385
R01 · FY2003 · NS
PS-1 in APP Processing and Synaptic Function$349,385
R01 · FY2003 · NS
PS1 &PS2 in Cortical Development and Notch Signaling$336,500
R01 · FY2003 · NS
Studies of Parkin KO Cells and Mice as PD Models$349,385
R01 · FY2002 · NS
PS-1 in APP Processing and Synaptic Function$349,385
R01 · FY2002 · NS
PS1 &PS2 in Cortical Development and Notch Signaling$335,098
R01 · FY2002 · NS
Development of mouse models of Parkinson's disease$0
P50 · FY2002 · NS
Studies of Parkin KO Cells and Mice as PD Models$349,385
R01 · FY2001 · NS
PS-1 in APP Processing and Synaptic Function$349,385
R01 · FY2001 · NS
Development of mouse models of Parkinson's disease$248,088
P50 · FY2001 · NS
Development of mouse models of Parkinson's disease$0
P50 · FY2001 · NS
Development of mouse models of Parkinson's disease$294,553
P50 · FY2000 · NS
Development of mouse models of Parkinson's disease$294,553
P50 · FY2000 · NS
Development of mouse models of Parkinson's disease$248,088
P50 · FY2000 · NS