← Leaderboards
John Y-J Shyy
Boston Children'S Hospital
$24,226,917
Attributed
$46,110,142
Total exposure
16
Grants
11
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4.6M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$46,110,142 · 16
By mechanism
R01$41,946,435 · 12
U54$3,311,632 · 2
R21$852,075 · 2
Top collaborators
- Shu Chien28 shared
- Shankar Subramaniam26 shared
- Jane C Burns6 shared
- Harold M Hoffman6 shared
- Adriana H Tremoulet6 shared
- Hong Chen4 shared
- Jinjun Shi4 shared
- Jin Zhang4 shared
Most similar at Boston Children'S Hospital
Same institution · by research overlap
- Hong Chen$23,928,447
- Jinjun Shi$13,516,816
- Sanjay Srivastava$27,960,573
Others in their field
Top investigators on “Endothelial Cells”
- Keri Hammel · The Emmes Company, Llc$41,089,609
- Martin Friedlander · Scripps Research Institute$38,298,285
- Michael Simons · Yale University$37,176,481
- Ajit P Varki · University Of California San Diego$34,208,221
- Joseph C Wu · Stanford University$33,648,524
- Jan E Schnitzer · Sidney Kimmel Cancer Center$31,414,677
Research focus
Endothelial CellsBlood VesselsIn VitroIn VivoShear StressMolecularVascular Endothelial CellGene ExpressionSignal TransductionResponseEndotheliumFunctional DisorderRegulationAtherosclerosisCellsBaseCell PhysiologyProteinsPatternHomeostasisPhenotypeMouse ModelMediatingInflammation
Grant awards (77)
Shear stress Regulation of Endothelial Glycolysis via METTL3-mediated RNA m6A Modification$826,373
R01 · FY2025 · HL · contact PI
The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis$734,885
R01 · FY2025 · HL
AMPK Regulation of ACE2 in Endothelial Health and Disease$656,945
R01 · FY2025 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$971,509
R01 · FY2024 · HL · contact PI
Shear stress Regulation of Endothelial Glycolysis via METTL3-mediated RNA m6A Modification$840,873
R01 · FY2024 · HL · contact PI
The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis$722,635
R01 · FY2024 · HL
AMPK Regulation of ACE2 in Endothelial Health and Disease$652,773
R01 · FY2024 · HL · contact PI
MAE-WEST SCORE Project 3 Animal$634,062
U54 · FY2024 · AG · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,014,578
R01 · FY2023 · HL · contact PI
The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis$769,426
R01 · FY2023 · HL
AMPK Regulation of ACE2 in Endothelial Health and Disease$673,114
R01 · FY2023 · HL · contact PI
MAE-WEST SCORE Project 3 Animal$576,738
U54 · FY2023 · AG · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,037,433
R01 · FY2022 · HL · contact PI
MAE-WEST SCORE Project 3 Animal$818,456
U54 · FY2022 · AG · contact PI
The Role of Adaptor Protein Disabled-2 in Maintaining Endothelial Cell Function in Atherosclerosis$812,576
R01 · FY2022 · HL
Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease$729,091
R01 · FY2022 · HL
AMPK Regulation of ACE2 in Endothelial Health and Disease$683,289
R01 · FY2022 · HL · contact PI
Nucleolin Regulation of miRome by Shear Stress$565,887
R01 · FY2022 · HL
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,062,530
R01 · FY2021 · HL · contact PI
MAE-WEST SCORE Project 3 Animal$818,962
U54 · FY2021 · AG · contact PI
Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease$730,641
R01 · FY2021 · HL
Nucleolin Regulation of miRome by Shear Stress$583,826
R01 · FY2021 · HL
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,057,617
R01 · FY2020 · HL
Endothelial Cell and Cardiomyocyte Dysfunction in Children with Kawasaki disease-like SARS-CoV-2 Induced Immune Activation$727,650
R01 · FY2020 · HL
Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease$716,260
R01 · FY2020 · HL
Nucleolin Regulation of miRome by Shear Stress$602,268
R01 · FY2020 · HL
MAE-WEST SCORE Project 3 Animal$463,414
U54 · FY2020 · AG · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,057,617
R01 · FY2019 · HL
Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease$710,525
R01 · FY2019 · HL
Nucleolin Regulation of miRome by Shear Stress$620,793
R01 · FY2019 · HL
Flow-Induced Endothelial Innate Immunity and Atherosclerosis Susceptibility$398,363
R01 · FY2019 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,057,617
R01 · FY2018 · HL
Innate Immune Activation and Endothelial Cell Dysfunction in Acute Kawasaki Disease$715,175
R01 · FY2018 · HL
Shear Regulation of MicroRNA Transportomes and Targetomes in Vascular Homeostasis$713,016
R01 · FY2018 · HL
Flow-Induced Endothelial Innate Immunity and Atherosclerosis Susceptibility$416,091
R01 · FY2018 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,057,617
R01 · FY2017 · HL
Shear Regulation of MicroRNA Transportomes and Targetomes in Vascular Homeostasis$730,591
R01 · FY2017 · HL
Flow-Induced Endothelial Innate Immunity and Atherosclerosis Susceptibility$424,713
R01 · FY2017 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$966,285
R01 · FY2016 · HL
Shear Regulation of MicroRNA Transportomes and Targetomes in Vascular Homeostasis$746,546
R01 · FY2016 · HL
Flow-Induced Endothelial Innate Immunity and Atherosclerosis Susceptibility$437,888
R01 · FY2016 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$968,450
R01 · FY2015 · HL
Shear Regulation of MicroRNA Transportomes and Targetomes in Vascular Homeostasis$762,456
R01 · FY2015 · HL
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,035,146
R01 · FY2014 · HL
MicroRNA in Functional Regulation of Endothelial Cells in Response to Flow$699,295
R01 · FY2014 · HL
The miRNA-mediated Translational De-suppression in Hypoxic Endothelium$189,875
R21 · FY2014 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,017,753
R01 · FY2013 · HL
MicroRNA in Functional Regulation of Endothelial Cells in Response to Flow$687,317
R01 · FY2013 · HL
Shear Stress, AMPK, and Endothelial Functions$344,777
R01 · FY2013 · HL · contact PI
Shear stress, SIRT1, and Arterial Stiffening$258,856
R01 · FY2013 · HL · contact PI
Shear stress, SIRT1, and Arterial Stiffening$99,285
R01 · FY2013 · HL · contact PI
Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis$1,090,718
R01 · FY2012 · HL
MicroRNA in Functional Regulation of Endothelial Cells in Response to Flow$784,276
R01 · FY2012 · HL
Shear stress, SIRT1, and Arterial Stiffening$376,200
R01 · FY2012 · HL · contact PI
Shear Stress, AMPK, and Endothelial Functions$364,170
R01 · FY2012 · HL · contact PI
The miRNA-mediated Translational De-suppression in Hypoxic Endothelium$228,000
R21 · FY2012 · HL · contact PI
MicroRNA in Functional Regulation of Endothelial Cells in Response to Flow$732,279
R01 · FY2011 · HL
Shear stress, SIRT1, and Arterial Stiffening$380,000
R01 · FY2011 · HL · contact PI
Shear Stress, AMPK, and Endothelial Functions$368,831
R01 · FY2011 · HL · contact PI
MicroRNA in Functional Regulation of Endothelial Cells in Response to Flow$41,360
R01 · FY2011 · HL
Shear stress, SIRT1, and Arterial Stiffening$380,000
R01 · FY2010 · HL · contact PI
Shear Stress, AMPK, and Endothelial Functions$371,348
R01 · FY2010 · HL · contact PI
Adiponetin and AMPK Biosensor$194,200
R21 · FY2010 · HL · contact PI
Shear Stress, AMPK, and Endothelial Functions$372,853
R01 · FY2009 · HL · contact PI
Adiponetin and AMPK Biosensor$240,000
R21 · FY2009 · HL · contact PI
Shear Stress, AMPK, and Endothelial Functions$61,755
R01 · FY2009 · HL · contact PI
Flow Regulation of SREBP in Atherosclerosis$350,493
R01 · FY2007 · HL · contact PI
Flow Regulation of SREBP in Atherosclerosis$360,962
R01 · FY2006 · HL · contact PI
Flow Regulation of SREBP in Atherosclerosis$368,452
R01 · FY2005 · HL
Flow Regulation of SREBP in Atherosclerosis$368,452
R01 · FY2004 · HL
SHEAR STRESS ENHANCEMENT OF SMOOTH MUSCLE CELL MIGRATION$331,875
R01 · FY2003 · HL
SHEAR STRESS ENHANCEMENT OF SMOOTH MUSCLE CELL MIGRATION$331,875
R01 · FY2002 · HL
STRAIN INDUCTION OF VSMC PROLIFERATION AND APOPTOSIS$248,307
R01 · FY2002 · HL
SHEAR STRESS ENHANCEMENT OF SMOOTH MUSCLE CELL MIGRATION$331,875
R01 · FY2001 · HL
STRAIN INDUCTION OF VSMC PROLIFERATION AND APOPTOSIS$241,075
R01 · FY2001 · HL
SHEAR STRESS ENHANCEMENT OF SMOOTH MUSCLE CELL MIGRATION$356,875
R01 · FY2000 · HL
STRAIN INDUCTION OF VSMC PROLIFERATION AND APOPTOSIS$234,053
R01 · FY2000 · HL