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Rik M. Derynck

Children'S Hospital Los Angeles

$18,375,653
Attributed
$18,375,653
Total exposure
15
Grants
9
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $1.3M · FY200520
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20

Funding mix

By agency

NIH$18,375,653 · 15

By mechanism

R01$12,956,113 · 4
P01$3,579,542 · 3
R21$1,137,424 · 3
P60$668,037 · 1
R13$22,500 · 2
P41$12,037 · 2

Top collaborators

No co-investigators on record.

Others in their field

Top investigators on “Phosphorylation

Research focus

PhosphorylationTransforming Growth FactorsSignal TransductionTransforming Growth Factor BetaResponseCellsTranscription FactorProteinsPlayReceptorTissuesSignal PathwayGrowth Factor ReceptorsLeadMediatingGene ExpressionBaseProgramsPathway InteractionsPhosphotransferasesCarcinomaRegulationEpithelial CellsAffect

Grant awards (65)

Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior$362,569
R01 · FY2020 · CA · contact PI
Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior$351,691
R01 · FY2019 · CA · contact PI
Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior$362,569
R01 · FY2018 · CA · contact PI
Regulatory non-Smad signaling in TGF-b-induced epithelial-mesenchymal transition$356,625
R01 · FY2018 · CA · contact PI
Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior$362,569
R01 · FY2017 · CA · contact PI
Regulatory non-Smad signaling in TGF-b-induced epithelial-mesenchymal transition$356,625
R01 · FY2017 · CA · contact PI
Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior$362,569
R01 · FY2016 · CA · contact PI
Regulatory non-Smad signaling in TGF-b-induced epithelial-mesenchymal transition$356,625
R01 · FY2016 · CA · contact PI
Regulatory non-Smad signaling in TGF-b-induced epithelial-mesenchymal transition$356,063
R01 · FY2015 · CA · contact PI
Functional crosstalk of TGF-beta/Smad signaling with methyl transferases$464,136
R01 · FY2014 · CA · contact PI
Regulatory non-Smad signaling in TGF-b-induced epithelial-mesenchymal transition$354,375
R01 · FY2014 · CA · contact PI
Functional crosstalk of TGF-beta/Smad signaling with methyl transferases$452,892
R01 · FY2013 · CA · contact PI
TGF-beta-induced non-Smad signaling events and cancer cell behavior$292,312
R01 · FY2013 · CA · contact PI
Functional crosstalk of TGF-beta/Smad signaling with methyl transferases$485,211
R01 · FY2012 · CA · contact PI
TGF-beta-induced non-Smad signaling events and cancer cell behavior$310,970
R01 · FY2012 · CA · contact PI
Functional crosstalk of TGF-beta/Smad signaling with methyl transferases$488,720
R01 · FY2011 · CA · contact PI
TGF-beta-induced non-Smad signaling events and cancer cell behavior$310,970
R01 · FY2011 · CA · contact PI
PRMT1 MEDIATED ARG METHYLATION OF INHIBITORY SMADS IN TGF-BETA SIGNALLING$10,271
P41 · FY2011 · RR · contact PI
Functional crosstalk of TGF-beta/Smad signaling with methyl transferases$505,640
R01 · FY2010 · CA · contact PI
TGF-beta-induced non-Smad signaling events and cancer cell behavior$320,588
R01 · FY2010 · CA · contact PI
TGF-b family signaling in cardiomyocyte differentiation from embryonic stem cells$193,125
R21 · FY2010 · HL · contact PI
PRMT1 MEDIATED ARG METHYLATION OF INHIBITORY SMADS IN TGF-BETA SIGNALLING$1,766
P41 · FY2010 · RR · contact PI
TGF-beta-induced non-Smad signaling events and cancer cell behavior$320,588
R01 · FY2009 · CA · contact PI
Non-Smad Mechanisms of TGFBeta Signaling$316,557
P01 · FY2009 · HL · contact PI
TGF-b family signaling in cardiomyocyte differentiation from embryonic stem cells$231,750
R21 · FY2009 · HL · contact PI
Conversion of pre-adipose cells into muscle cells$169,950
R21 · FY2009 · AR · contact PI
TGF-Beta and Smad-mediated regulation of gene expression$89,939
R01 · FY2009 · CA · contact PI
TGF-Beta and Smad-mediated regulation of gene expression$470,607
R01 · FY2008 · CA · contact PI
Non-Smad Mechanisms of TGFBeta Signaling$398,035
P01 · FY2008 · HL · contact PI
Conversion of pre-adipose cells into muscle cells$203,940
R21 · FY2008 · AR · contact PI
TGF-beta receptor sumoylation and cell behavior$154,209
R21 · FY2008 · CA · contact PI
TGF-Beta and Smad-mediated regulation of gene expression$468,740
R01 · FY2007 · CA · contact PI
Non-Smad Mechanisms of TGFBeta Signaling$389,696
P01 · FY2007 · HL · contact PI
TGF-beta receptor sumoylation and cell behavior$184,450
R21 · FY2007 · CA · contact PI
TGF-Beta and Smad-mediated regulation of gene expression$471,377
R01 · FY2006 · CA · contact PI
Non-Smad Mechanisms of TGFBeta Signaling$365,289
P01 · FY2006 · HL · contact PI
TGF-Beta and Smad-mediated regulation of gene expression$455,814
R01 · FY2005 · CA
Non-Smad Mechanisms of TGFBeta Signaling$375,675
P01 · FY2005 · HL
FUNCTION OF TRANSMEMBRANE TGF A ASSOCIATED PROTEINS$300,891
R01 · FY2005 · CA
TGF-ALPHA PROCESSING IN ORAL CANCER$163,531
P01 · FY2005 · DE
TGF-Beta and Smad-mediated regulation of gene expression$442,801
R01 · FY2004 · CA
FUNCTION OF TRANSMEMBRANE TGF A ASSOCIATED PROTEINS$300,891
R01 · FY2004 · CA
TGF-ALPHA PROCESSING IN ORAL CANCER$158,768
P01 · FY2004 · DE
MECHANISMS OF TGF B RECEPTOR AND SMAD SIGNALING$413,770
R01 · FY2003 · CA
FUNCTION OF TRANSMEMBRANE TGF A ASSOCIATED PROTEINS$300,891
R01 · FY2003 · CA
TGF-ALPHA PROCESSING IN ORAL CANCER$145,295
P01 · FY2003 · DE
SKELETAL AUGMENTATION BY MESENCHYMAL/OSTEOBLAST TRANSDIFFERENTIATION$118,977
P60 · FY2003 · DE
TGF-Beta Superfamily: Signaling and Development$9,000
R13 · FY2003 · HD
MECHANISMS OF TGF B RECEPTOR AND SMAD SIGNALING$401,850
R01 · FY2002 · CA
FUNCTION OF TRANSMEMBRANE TGF A ASSOCIATED PROTEINS$267,459
R01 · FY2002 · CA
TGF BETA SIGNALING AND APOPTOSIS$187,536
P01 · FY2002 · HL
TGF BETA SIGNALING AND APOPTOSIS$187,536
P01 · FY2002 · HL
TGF-ALPHA PROCESSING IN ORAL CANCER$145,295
P01 · FY2002 · DE
SKELETAL AUGMENTATION BY MESENCHYMAL/OSTEOBLAST TRANSDIFFERENTIATION$118,977
P60 · FY2002 · DE
MECHANISMS OF TGF B RECEPTOR AND SMAD SIGNALING$390,276
R01 · FY2001 · CA
FUNCTION OF TRANSMEMBRANE TGF A ASSOCIATED PROTEINS$267,459
R01 · FY2001 · CA
TGF BETA SIGNALING AND APOPTOSIS$187,536
P01 · FY2001 · HL
TGF-ALPHA PROCESSING IN ORAL CANCER$145,295
P01 · FY2001 · DE
SKELETAL AUGMENTATION BY MESENCHYMAL/OSTEOBLAST TRANSDIFFERENTIATION$118,977
P60 · FY2001 · DE
FASEB CONFERENCE ON TGF-BETA SUPERFAMILY$13,500
R13 · FY2001 · HD
MECHANISMS OF TGF B RECEPTOR AND SMAD SIGNALING$379,041
R01 · FY2000 · CA
TGF BETA SIGNALING AND APOPTOSIS$225,962
P01 · FY2000 · HL
TGF BETA SIGNALING AND APOPTOSIS$187,536
P01 · FY2000 · HL
SKELETAL AUGMENTATION BY MESENCHYMAL/OSTEOBLAST TRANSDIFFERENTIATION$175,491
P60 · FY2000 · DE
SKELETAL AUGMENTATION BY MESENCHYMAL/OSTEOBLAST TRANSDIFFERENTIATION$135,615
P60 · FY2000 · DE