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Irwin M Chaiken

University Of Pennsylvania

$15,499,914
Attributed
$17,078,741
Total exposure
21
Grants
17
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.2M · FY200522
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22

Funding mix

By agency

NIH$56,013,056 · 23

By mechanism

P01$45,596,735 · 10
R01$7,616,550 · 6
R21$1,258,297 · 3
P30$1,175,937 · 2
S10$364,883 · 1
P41$654 · 1

Top collaborators

Most similar at University Of Pennsylvania

Same institution · by research overlap

Others in their field

Top investigators on “Hiv Envelope Protein Gp120

Research focus

Hiv Envelope Protein Gp120Hiv-1CellsInhibitor/AntagonistDesignBinding SitesEnv Gene ProductsVirusProgramsStructureInfectionBaseProteinsReceptor CellPropertyAcquired Immunodeficiency SyndromeViralMolecularVariantReceptor BindingSmall MoleculeSitePeptidesReceptor

Grant awards (107)

Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,898,052
P01 · FY2022 · AI · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$343,785
P01 · FY2022 · AI · contact PI
Core C Administrative Core$39,071
P01 · FY2022 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,902,856
P01 · FY2021 · AI · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$344,656
P01 · FY2021 · AI · contact PI
Bifunctional Chimeras Targeting Both HIV-1 Env and Host Cell Co-receptors$200,000
R01 · FY2021 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$76,417
P01 · FY2021 · AI · contact PI
Core C Administrative Core$39,168
P01 · FY2021 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,907,518
P01 · FY2020 · AI · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$345,500
P01 · FY2020 · AI · contact PI
Bifunctional Chimeras Targeting Both HIV-1 Env and Host Cell Co-receptors$200,000
R01 · FY2020 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$74,282
P01 · FY2020 · AI · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$74,282
P01 · FY2020 · AI · contact PI
Core C Administrative Core$39,263
P01 · FY2020 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,911,904
P01 · FY2019 · AI · contact PI
Biacore S200 Surface Plasmon Resonance Instrument for a Shared Resources Facility$364,883
S10 · FY2019 · OD · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$345,514
P01 · FY2019 · AI · contact PI
Bifunctional Chimeras Targeting Both HIV-1 Env and Host Cell Co-receptors$200,000
R01 · FY2019 · AI · contact PI
Core C Administrative Core$39,116
P01 · FY2019 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,983,930
P01 · FY2018 · GM · contact PI
Dual-action virolytic entry inhibitors against HIV-1$469,853
R01 · FY2018 · GM · contact PI
HIV-1 Env Trimer Antagonism and Inactivation by Small Molecule Peptidomimetics$315,434
P01 · FY2018 · GM · contact PI
Bifunctional Chimeras Targeting Both HIV-1 Env and Host Cell Co-receptors$200,000
R01 · FY2018 · AI · contact PI
Core C Administrative Core$120,079
P01 · FY2018 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,912,085
P01 · FY2017 · GM · contact PI
Dual-action virolytic entry inhibitors against HIV-1$469,853
R01 · FY2017 · GM · contact PI
PEPTIDE-BASED APPROACHES TO ANTAGONISM AND MECHANISM OF HIV-1 ENVELOPE$309,522
P01 · FY2017 · GM · contact PI
Bifunctional Chimeras Targeting Both HIV-1 Env and Host Cell Co-receptors$200,000
R01 · FY2017 · AI · contact PI
Dual-action virolytic entry inhibitors against HIV-1$50,000
R01 · FY2017 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,912,085
P01 · FY2016 · GM · contact PI
Dual-action virolytic entry inhibitors against HIV-1$469,853
R01 · FY2016 · GM · contact PI
PEPTIDE-BASED APPROACHES TO ANTAGONISM AND MECHANISM OF HIV-1 ENVELOPE$309,522
P01 · FY2016 · GM · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$289,340
R01 · FY2016 · GM · contact PI
Dual-action virolytic entry inhibitors against HIV-1$96,478
R01 · FY2016 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$85,728
P01 · FY2016 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,912,085
P01 · FY2015 · GM · contact PI
Dual-action virolytic entry inhibitors against HIV-1$490,878
R01 · FY2015 · GM · contact PI
PEPTIDE-BASED APPROACHES TO ANTAGONISM AND MECHANISM OF HIV-1 ENVELOPE$308,642
P01 · FY2015 · GM · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$289,340
R01 · FY2015 · GM · contact PI
Antiviral Synergism of Inhibitors Targeting HIV-1 Env and Host Cell Co-Receptors$200,000
R01 · FY2015 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,912,085
P01 · FY2014 · GM · contact PI
PEPTIDE-BASED APPROACHES TO ANTAGONISM AND MECHANISM OF HIV-1 ENVELOPE$301,523
P01 · FY2014 · GM · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$289,340
R01 · FY2014 · GM · contact PI
Antiviral Synergism of Inhibitors Targeting HIV-1 Env and Host Cell Co-Receptors$200,000
R01 · FY2014 · AI · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$50,000
R01 · FY2014 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$43,881
P01 · FY2014 · GM · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$5,190
R01 · FY2014 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,993,835
P01 · FY2013 · GM · contact PI
PEPTIDE-BASED APPROACHES TO ANTAGONISM AND MECHANISM OF HIV-1 ENVELOPE$383,273
P01 · FY2013 · GM · contact PI
Multivalent Env gp120 Targeting Gold Nanoparticle Virucides of HIV-1$285,271
R01 · FY2013 · GM · contact PI
Antiviral Synergism of Inhibitors Targeting HIV-1 Env and Host Cell Co-Receptors$200,000
R01 · FY2013 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$378,182
P01 · FY2012 · GM · contact PI
HIV-1 gp120 Conformational Transitions in Activation and Antagonism$189,540
R21 · FY2012 · AI · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$189,090
P01 · FY2012 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,687,060
P01 · FY2011 · GM · contact PI
HIV-1 gp120 Conformational Transitions in Activation and Antagonism$238,894
R21 · FY2011 · AI · contact PI
Peptide-inspired Competitive and allosteric inhibitors of HIV entry$221,658
P01 · FY2011 · GM · contact PI
Protein technologies$202,906
P01 · FY2011 · GM · contact PI
Epitope-Focused HIV-1 Envelope Vaccine for HIV-1/AIDS$191,110
R21 · FY2011 · AI · contact PI
DYNAMICS OF VIROLOGICAL SYNAPSES$654
P41 · FY2011 · RR · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,705,332
P01 · FY2010 · GM · contact PI
Epitope-Focused HIV-1 Envelope Vaccine for HIV-1/AIDS$250,008
R21 · FY2010 · AI · contact PI
Peptide-inspired Competitive and allosteric inhibitors of HIV entry$223,876
P01 · FY2010 · GM · contact PI
Protein technologies$204,935
P01 · FY2010 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,671,996
P01 · FY2009 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$519,761
P01 · FY2009 · GM · contact PI
Peptide-inspired Competitive and allosteric inhibitors of HIV entry$219,562
P01 · FY2009 · GM · contact PI
Protein technologies$200,981
P01 · FY2009 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,622,544
P01 · FY2008 · GM · contact PI
Peptide-inspired Competitive and allosteric inhibitors of HIV entry$213,178
P01 · FY2008 · GM · contact PI
Protein technologies$195,137
P01 · FY2008 · GM · contact PI
Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry$1,711,101
P01 · FY2007 · GM · contact PI
Peptide-inspired Competitive and allosteric inhibitors of HIV entry$281,288
P01 · FY2007 · GM · contact PI
Protein technologies$260,481
P01 · FY2007 · GM · contact PI
CVN-12p1 Chimeras and Combinations for AIDS Microbiocides$173,870
R21 · FY2007 · AI · contact PI
Structure-Based CD-4-gp120 Antagonism$1,651,282
P01 · FY2006 · GM · contact PI
CVN-12p1 Chimeras and Combinations for AIDS Microbiocides$214,875
R21 · FY2006 · AI · contact PI
MINIPROTEIN MIMETICS$157,210
P01 · FY2006 · GM · contact PI
Structure-Based CD-4-gp120 Antagonism$1,652,278
P01 · FY2005 · GM
Structure-Based CD-4-gp120 Antagonism$1,618,990
P01 · FY2004 · GM
Structural Mechanism of IL5-Receptor Subunit Recruitment$323,444
R01 · FY2004 · GM
INTERLEUKIN 5 RECEPTOR RECOGNITION, MIMETICS, ANTAGONISM$300,000
R01 · FY2004 · AI
Structure-Based CD-4-gp120 Antagonism$1,575,383
P01 · FY2003 · GM
Structural Mechanism of IL5-Receptor Subunit Recruitment$314,196
R01 · FY2003 · GM
INTERLEUKIN 5 RECEPTOR RECOGNITION, MIMETICS, ANTAGONISM$300,000
R01 · FY2003 · AI
Structure-Based CD-4-gp120 Antagonism$1,345,280
P01 · FY2002 · GM
Structure-Based CD-4-gp120 Antagonism$454,663
P01 · FY2002 · GM
INTERLEUKIN 5 RECEPTOR RECOGNITION, MIMETICS, ANTAGONISM$317,000
R01 · FY2002 · AI
CORE--BIOSENSOR/INTERACTION ANALYSIS FACILITY$228,564
P30 · FY2002 · CA
Structural Mechanism of IL5-Receptor Subunit Recruitment$169,939
R01 · FY2002 · GM
MINIPROTEIN MIMETICS$157,210
P01 · FY2002 · GM
MINIPROTEIN MIMETICS$157,210
P01 · FY2002 · GM
Structural Mechanism of IL5-Receptor Subunit Recruitment$146,210
R01 · FY2002 · GM
CORE--STRUCTURAL BIOLOGY FACILITY$0
P30 · FY2002 · AI
STRUCTURE-BASED CD4-GP120 ANTAGONISM$823,986
P01 · FY2001 · GM
INTERLEUKIN 5 RECEPTOR RECOGNITION, MIMETICS, ANTAGONISM$317,000
R01 · FY2001 · AI
Structural Mechanism of IL5-Receptor Subunit Recruitment$315,636
R01 · FY2001 · GM
CORE--BIOSENSOR/INTERACTION ANALYSIS FACILITY$276,694
P30 · FY2001 · CA
CORE--BIOSENSOR/INTERACTION ANALYSIS FACILITY$228,564
P30 · FY2001 · CA
MINIPROTEIN MIMETICS$157,210
P01 · FY2001 · GM
CORE--STRUCTURAL BIOLOGY FACILITY$0
P30 · FY2001 · AI
CORE--STRUCTURAL BIOLOGY FACILITY$0
P30 · FY2001 · AI
STRUCTURE-BASED CD4-GP120 ANTAGONISM$800,644
P01 · FY2000 · GM
CORE--BIOSENSOR/INTERACTION ANALYSIS FACILITY$276,694
P30 · FY2000 · CA
HUMAN INTERLEUKIN 5 RECOGNITION, MIMETICS, ANTAGONISTS$257,729
R01 · FY2000 · AI
CORE--STRUCTURAL BIOLOGY FACILITY$165,421
P30 · FY2000 · AI
MINIPROTEIN MIMETICS$151,228
P01 · FY2000 · GM