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Hugh Lee Sweeney

University Of Pennsylvania

$44,337,022
Attributed
$45,494,120
Total exposure
39
Grants
28
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $7.7M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$92,340,704 · 44

By mechanism

U54$51,911,070 · 12
R01$21,138,857 · 8
P50$11,411,439 · 10
P01$5,452,169 · 7
R33$973,747 · 1
T32$530,051 · 1

Most similar at University Of Pennsylvania

Same institution · by research overlap

Others in their field

Top investigators on “Cells

Research focus

CellsMuscleMuscular DystrophiesActinsLeadMouse ModelInflammationDesignPharmaceutical PreparationsMutationMyosin AtpaseNatural RegenerationIn VitroStructureMyocardiumFibrosisRepairedGene TherapyProteinsInsightPreventDisease ProgressionMotorFunding

Grant awards (161)

Addressing Shortcomings of AAV GeneTherapies for the Muscular Dystrophies$1,347,536
P50 · FY2025 · HD · contact PI
Project 1 - Sweeney_Hammers$262,991
P50 · FY2025 · HD · contact PI
Admin Core - Sweeney_McNally(NU)$25,571
P50 · FY2025 · HD · contact PI
Understanding and Improving Therapies for the Muscular Dystrophies$1,546,142
P50 · FY2024 · AR · contact PI
Modifying heart and skeletal muscle in muscular dystrophy$486,520
P50 · FY2024 · AR · contact PI
Drug Discovery for First-In-Class Myosin 10 Inhibitors as a Novel Target for Glioblastoma$475,793
R33 · FY2024 · NS
Myosin 18 and its role in skeletal muscle$400,428
R01 · FY2024 · AR · contact PI
Potential therapies for the muscular dystrophies$358,894
P50 · FY2024 · AR · contact PI
Core A - Admin Core$30,822
P50 · FY2024 · AR · contact PI
Understanding and Improving Therapies for the Muscular Dystrophies$1,549,615
P50 · FY2023 · AR · contact PI
Drug Discovery for First-In-Class Myosin 10 Inhibitors as a Novel Target for Glioblastoma$497,954
R33 · FY2023 · NS
Modifying heart and skeletal muscle in muscular dystrophy$486,520
P50 · FY2023 · AR · contact PI
Myosin 18 and its role in skeletal muscle$412,813
R01 · FY2023 · AR · contact PI
Myo10-Driven Filopodia in Skeletal Muscle$375,996
R01 · FY2023 · AR · contact PI
Potential therapies for the muscular dystrophies$358,894
P50 · FY2023 · AR · contact PI
Core A - Admin Core$34,295
P50 · FY2023 · AR · contact PI
Understanding and Improving Therapies for the Muscular Dystrophies$1,549,615
P50 · FY2022 · AR · contact PI
Modifying heart and skeletal muscle in muscular dystrophy$486,520
P50 · FY2022 · AR · contact PI
Myosin 18 and its role in skeletal muscle$408,684
R01 · FY2022 · AR · contact PI
Myo10-Driven Filopodia in Skeletal Muscle$372,236
R01 · FY2022 · AR · contact PI
Potential therapies for the muscular dystrophies$358,894
P50 · FY2022 · AR · contact PI
Structure and Function of Myosin VI$351,056
R01 · FY2022 · DC · contact PI
Drug Discovery for First-In-Class Myosin 10 Inhibitors as a Novel Target for Glioblastoma$229,400
R61 · FY2022 · NS
Drug Discovery for First-In-Class Myosin 10 Inhibitors as a Novel Target for Glioblastoma$185,371
R61 · FY2022 · NS
Core A - Admin Core$34,295
P50 · FY2022 · AR · contact PI
Understanding and Improving Therapies for the Muscular Dystrophies$1,588,673
P50 · FY2021 · AR · contact PI
Modifying heart and skeletal muscle in muscular dystrophy$512,453
P50 · FY2021 · AR · contact PI
Myosin 18 and its role in skeletal muscle$400,428
R01 · FY2021 · AR · contact PI
Myo10-Driven Filopodia in Skeletal Muscle$364,716
R01 · FY2021 · AR · contact PI
Potential therapies for the muscular dystrophies$358,894
P50 · FY2021 · AR · contact PI
Structure and Function of Myosin VI$351,056
R01 · FY2021 · DC · contact PI
Core A - Admin Core$34,295
P50 · FY2021 · AR · contact PI
Myosin 18 and its role in skeletal muscle$425,938
R01 · FY2020 · AR · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat - Administrative Supplement$403,938
U54 · FY2020 · AR · contact PI
Myo10-Driven Filopodia in Skeletal Muscle$375,996
R01 · FY2020 · AR · contact PI
Structure and Function of Myosin VI$351,056
R01 · FY2020 · DC · contact PI
FAILED REGENERATION IN THE MUSCULAR DYSTROPHIES: INFLAMMATION, FIBROSIS AND FAT$1,504,473
U54 · FY2019 · AR · contact PI
Assessing and Modulating inflammation and Fibrosis in Dystrophic Muscle$530,344
U54 · FY2019 · AR · contact PI
Myo10-Driven Filopodia in Skeletal Muscle$375,996
R01 · FY2019 · AR · contact PI
Structure and Function of Myosin VI$351,056
R01 · FY2019 · DC · contact PI
MAPPING MODIFIERS OF CARDIOMYOPATHY IN MUSCULAR DYSTROPHY$273,443
U54 · FY2019 · AR · contact PI
FAILED REGENERATION IN THE MUSCULAR DYSTROPHIES: INFLAMMATION, FIBROSIS AND FAT$1,513,351
U54 · FY2018 · AR · contact PI
Assessing and Modulating inflammation and Fibrosis in Dystrophic Muscle$534,097
U54 · FY2018 · AR · contact PI
Structure and Function of Myosin VI$366,938
R01 · FY2018 · DC · contact PI
MAPPING MODIFIERS OF CARDIOMYOPATHY IN MUSCULAR DYSTROPHY$278,568
U54 · FY2018 · AR · contact PI
FAILED REGENERATION IN THE MUSCULAR DYSTROPHIES: INFLAMMATION, FIBROSIS AND FAT$1,522,536
U54 · FY2017 · AR · contact PI
Assessing and Modulating inflammation and Fibrosis in Dystrophic Muscle$538,141
U54 · FY2017 · AR · contact PI
MAPPING MODIFIERS OF CARDIOMYOPATHY IN MUSCULAR DYSTROPHY$283,710
U54 · FY2017 · AR · contact PI
FAILED REGENERATION IN THE MUSCULAR DYSTROPHIES: INFLAMMATION, FIBROSIS AND FAT$1,533,675
U54 · FY2016 · AR · contact PI
Myosin Mutations Leading to Vascular Diseases$555,833
P01 · FY2016 · HL · contact PI
Assessing and Modulating inflammation and Fibrosis in Dystrophic Muscle$541,096
U54 · FY2016 · AR · contact PI
Structure and function of Myosin VI$431,310
R01 · FY2016 · DC · contact PI
MAPPING MODIFIERS OF CARDIOMYOPATHY IN MUSCULAR DYSTROPHY$288,703
U54 · FY2016 · AR · contact PI
FAILED REGENERATION IN THE MUSCULAR DYSTROPHIES: INFLAMMATION, FIBROSIS AND FAT$1,597,511
U54 · FY2015 · AR · contact PI
Assessing and Modulating inflammation and Fibrosis in Dystrophic Muscle$556,465
U54 · FY2015 · AR · contact PI
Myosin Mutations Leading to Vascular Diseases$441,673
P01 · FY2015 · HL · contact PI
Structure and function of Myosin VI$439,497
R01 · FY2015 · DC · contact PI
MAPPING MODIFIERS OF CARDIOMYOPATHY IN MUSCULAR DYSTROPHY$306,050
U54 · FY2015 · AR · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$1,617,974
U54 · FY2014 · AR · contact PI
Structure and function of Myosin VI$454,177
R01 · FY2014 · DC · contact PI
Myosin Mutations Leading to Vascular Diseases$432,771
P01 · FY2014 · HL · contact PI
Co-Fund NIHLBI$400,000
U54 · FY2014 · AR · contact PI
Assessing and Modulating the role of inflammation and Fibrosis in the Dystrophic$248,950
U54 · FY2014 · AR · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$1,553,843
U54 · FY2013 · AR · contact PI
Structure and function of Myosin VI$431,469
R01 · FY2013 · DC · contact PI
Co-Fund NIHLBI$380,000
U54 · FY2013 · AR · contact PI
Myosin Mutations Leading to Vascular Diseases$376,910
P01 · FY2013 · HL · contact PI
Assessing and Modulating the role of inflammation and Fibrosis in the Dystrophic$315,816
U54 · FY2013 · AR · contact PI
Cellular models of microvillus inclusion disease$231,600
R21 · FY2013 · DK · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$1,645,986
U54 · FY2012 · AR · contact PI
Structure and function of Myosin VI$469,177
R01 · FY2012 · DC · contact PI
Assessing and Modulating the role of inflammation and Fibrosis in the Dystrophic$451,620
U54 · FY2012 · AR · contact PI
CO_FUND$400,000
U54 · FY2012 · AR · contact PI
Cellular models of microvillus inclusion disease$200,000
R21 · FY2012 · DK · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$23,683
U54 · FY2012 · AR · contact PI
Development of small molecules for delaying the progression of muscular dystrophy$3,114,403
U54 · FY2011 · NS · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$1,586,518
U54 · FY2011 · AR · contact PI
Development of Novel Small Molecules for Delaying the Progression of Muscular Dys$519,110
U54 · FY2011 · NS · contact PI
Structure and function of Myosin VI$401,242
R01 · FY2011 · DC · contact PI
CO_FUND$400,000
U54 · FY2011 · AR · contact PI
Assessing and Modulating the role of inflammation and Fibrosis in the Dystrophic$349,977
U54 · FY2011 · AR · contact PI
Efficacy Assessment Core$119,327
U54 · FY2011 · NS · contact PI
Development of novel small molecules for delaying the progression of muscular dy$3,067,726
U54 · FY2010 · NS · contact PI
Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat$1,616,993
U54 · FY2010 · AR · contact PI
Development of Novel Small Molecules for Delaying the Progression of Muscular Dys$514,797
U54 · FY2010 · NS · contact PI
Myosin Isozymes$472,912
R01 · FY2010 · AR · contact PI
Assessing and Modulating the role of inflammation and Fibrosis in the Dystrophic$424,013
U54 · FY2010 · AR · contact PI
NHLBI Co-funding (Budget Period 06)$408,173
U54 · FY2010 · AR · contact PI
Structure and function of Myosin VI$405,295
R01 · FY2010 · DC · contact PI
Efficacy Assessment Core$115,727
U54 · FY2010 · NS · contact PI
Development of novel small molecules for delaying the progression of muscular dy$3,022,413
U54 · FY2009 · NS · contact PI
Modulation of Muscle Growth for the Muscular Dystrophies$1,558,924
U54 · FY2009 · AR · contact PI
Development of Novel Small Molecules for Delaying the Progression of Muscular Dys$510,603
U54 · FY2009 · NS · contact PI
Protease Inhibition as Possible therapy for Muscular Dystrophy$470,464
U54 · FY2009 · AR · contact PI
Myosin Isozymes$464,670
R01 · FY2009 · AR · contact PI
Structure and function of Myosin VI$400,402
R01 · FY2009 · DC · contact PI
Efficacy Assessment Core$112,236
U54 · FY2009 · NS · contact PI
Development of novel small molecules for delaying the progression of muscular dy$2,978,431
U54 · FY2008 · NS · contact PI
Modulation of Muscle Growth for the Muscular Dystrophies$1,558,924
U54 · FY2008 · AR · contact PI
Development of Novel Small Molecules for Delaying the Progression of Muscular Dys$506,517
U54 · FY2008 · NS · contact PI
Protease Inhibition as Possible therapy for Muscular Dystrophy$470,464
U54 · FY2008 · AR · contact PI
Myosin Isozymes$452,027
R01 · FY2008 · AR · contact PI
CARDIAC GENE THERAPY$436,564
P01 · FY2008 · HL · contact PI
Structure and function of Myosin VI$391,667
R01 · FY2008 · DC · contact PI
Regulation and Mechano-Chemistry of Myosins V and VI$262,228
P01 · FY2008 · AR · contact PI
Efficacy Assessment Core$108,825
U54 · FY2008 · NS · contact PI
Development of novel small molecules for delaying the progression of muscular dy$2,934,156
U54 · FY2007 · NS · contact PI
Modulation of Muscle Growth for the Muscular Dystrophies$1,559,950
U54 · FY2007 · AR · contact PI
Development of Novel Small Molecules for Delaying the Progression of Muscular Dys$536,586
U54 · FY2007 · NS · contact PI
Myosin Isozymes$448,729
R01 · FY2007 · AR · contact PI
CARDIAC GENE THERAPY$435,000
P01 · FY2007 · HL · contact PI
Protease Inhibition as Possible therapy for Muscular Dystrophy$408,273
U54 · FY2007 · AR · contact PI
Structure and function of Myosin VI$403,242
R01 · FY2007 · DC · contact PI
Understanding and Preventing Disuse Atrophy$336,267
R01 · FY2007 · AR · contact PI
Regulation and Mechano-Chemistry of Myosins V and VI$243,660
P01 · FY2007 · AR · contact PI
Efficacy Assessment Core$228,582
U54 · FY2007 · NS · contact PI
Administrative & Training Core$194,475
U54 · FY2007 · AR · contact PI
Modulation of Muscle Growth for the Muscular Dystrophies$1,608,144
U54 · FY2006 · AR · contact PI
Myosin Isozymes$462,972
R01 · FY2006 · AR · contact PI
CARDIAC GENE THERAPY$421,599
P01 · FY2006 · HL · contact PI
Structure and Function of Myosin VI$395,290
R01 · FY2006 · AR · contact PI
Understanding and Preventing Disuse Atrophy$346,310
R01 · FY2006 · AR · contact PI
Modulation of Muscle Growth for the Muscular Dystrophies$1,662,366
U54 · FY2005 · AR
CARDIAC GENE THERAPY$411,439
P01 · FY2005 · HL
Structure and Function of Myosin VI$403,640
R01 · FY2005 · AR
Understanding and Preventing Disuse Atrophy$384,363
R01 · FY2005 · AR
Muscle: Contractile Proteins GRC 2005$22,000
R13 · FY2005 · AR
BIOENGINEERING RESEARCH PARTNERSHIP--MUSCULAR DYSTROPHY$699,965
R01 · FY2004 · AR
Structure and Function of Myosin VI$423,009
R01 · FY2004 · AR
CARDIAC GENE THERAPY$400,484
P01 · FY2004 · HL
Understanding and Preventing Disuse Atrophy$384,363
R01 · FY2004 · AR
New Directions in Biology and Disease of Skeletal Muscle$10,000
U13 · FY2004 · AR
BIOENGINEERING RESEARCH PARTNERSHIP--MUSCULAR DYSTROPHY$681,377
R01 · FY2003 · AR
Structure and Function of Myosin VI$413,976
R01 · FY2003 · AR
Understanding and Preventing Disuse Atrophy$384,363
R01 · FY2003 · AR
MYOSIN ISOZYMES$363,077
R01 · FY2003 · AR
TRAINING IN MUSCLE BIOLOGY$167,450
T32 · FY2003 · AR
New Directions in Biology and Disease of Skeletal Muscle$30,000
U13 · FY2003 · AR
BIOENGINEERING RESEARCH PARTNERSHIP--MUSCULAR DYSTROPHY$663,440
R01 · FY2002 · AR
Structure and Function of Myosin VI$419,832
R01 · FY2002 · AR
MYOSIN ISOZYMES$352,500
R01 · FY2002 · AR
IN VIVO STUDIES OF TROPONIN T FUNCTION$310,279
R01 · FY2002 · HL
CARDIAC GENE THERAPY$126,320
P01 · FY2002 · HL
TRAINING IN MUSCLE BIOLOGY$122,954
T32 · FY2002 · AR
DESIGN AND TUNING OF THE SMOOTH/NONMUSCLE MYOSIN MOTOR$0
P01 · FY2002 · HL
CORE--PROTEIN ENGINEERING$0
P01 · FY2002 · HL
BIOENGINEERING RESEARCH PARTNERSHIP--MUSCULAR DYSTROPHY$649,379
R01 · FY2001 · AR
MYOSIN ISOZYMES$342,236
R01 · FY2001 · AR
TRAINING IN MUSCLE BIOLOGY$126,323
T32 · FY2001 · AR
Molecular Motors$15,000
R13 · FY2001 · AR
CORE--PROTEIN ENGINEERING$0
P01 · FY2001 · HL
CARDIAC GENE THERAPY$0
P01 · FY2001 · HL
DESIGN AND TUNING OF THE SMOOTH/NONMUSCLE MYOSIN MOTOR$0
P01 · FY2001 · HL
BIOENGINEERING RESEARCH PARTNERSHIP--MUSCULAR DYSTROPHY$639,745
R01 · FY2000 · AR
MYOSIN ISOZYMES$332,265
R01 · FY2000 · AR
CORE--PROTEIN ENGINEERING$288,917
P01 · FY2000 · HL
DESIGN AND TUNING OF THE SMOOTH/NONMUSCLE MYOSIN MOTOR$288,917
P01 · FY2000 · HL
CARDIAC GENE THERAPY$250,769
P01 · FY2000 · HL
TRAINING IN MUSCLE BIOLOGY$113,324
T32 · FY2000 · AR
GENE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY$79,085
P01 · FY2000 · AR
ASSESSMENT OF DYSTROPHIN FUNCTION$0
P01 · FY2000 · AR