GGrantIndex
← Leaderboards

Megan Sykes

Columbia University Health Sciences

Google Scholar ↗PubMed ↗ORCID ↗
$56,546,810
Attributed
$64,486,993
Total exposure
47
Grants
42
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $10.6M · FY2005–25
$20M$15M$10M$5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$124,809,502 · 51

By mechanism

P01$69,070,247 · 19
R01$25,401,712 · 12
U19$14,685,370 · 7
U01$4,262,184 · 1
UC4$3,750,944 · 1
N01$2,198,719 · 1

Top collaborators

Most similar at Columbia University Health Sciences

Same institution · by research overlap

Others in their field

Top investigators on “T-Lymphocyte”

Research focus

T-LymphocyteCellsChimerismTransplantationHematopoieticB-LymphocytesAntigensHematopoietic Stem CellsImmune SystemBone MarrowAllogenicImmuneRegulatory T-LymphocyteOrganFamily SuidaeThymus GlandMouse ModelResponseTissuesAnimalsPreventImmune ResponseAnimal ModelXenograft Procedure

Grant awards (192)

A Tolerance Approach to Xenotransplantation$3,181,738
P01 · FY2025 · AI · contact PI
Preclinical Studies of Living and Deceased Donor Liver Allograft Tolerance$1,286,273
R01 · FY2025 · AI · contact PI
Understanding thymic epithelial and hematopoietic stem cell-intrinsic immune abnormalities driving T1D in optimized HIS mouse models$1,207,770
UG3 · FY2025 · DK · contact PI
Thymic selection abnormalities in Type 1 Diabetes$763,729
R01 · FY2025 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$540,503
P01 · FY2025 · AI · contact PI
Achieving Xenograft Tolerance through Mixed Chimerism$526,083
P01 · FY2025 · AI · contact PI
A Tolerance Approach to Xenotransplantation$85,672
P01 · FY2025 · AI · contact PI
Administrative and Data Management Core$80,620
P01 · FY2025 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,278,603
P01 · FY2024 · AI · contact PI
Thymic selection abnormalities in Type 1 Diabetes$763,729
R01 · FY2024 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$534,474
P01 · FY2024 · AI · contact PI
Training in Translational Immunology Research$302,148
T32 · FY2024 · AI · contact PI
Administrative and Data Management Core$126,606
P01 · FY2024 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$42,836
P01 · FY2024 · AI · contact PI
A Tolerance Approach to Xenotransplantation$42,836
P01 · FY2024 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,278,603
P01 · FY2023 · AI · contact PI
Thymic selection abnormalities in Type 1 Diabetes$763,729
R01 · FY2023 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$534,475
P01 · FY2023 · AI · contact PI
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems$425,000
U01 · FY2023 · DK · contact PI
Training in Translational Immunology Research$298,237
T32 · FY2023 · AI · contact PI
Administrative and Data Management Core$126,426
P01 · FY2023 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,294,103
P01 · FY2022 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$1,452,113
U19 · FY2022 · AI · contact PI
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems$951,710
U01 · FY2022 · DK · contact PI
Project-002$774,788
U19 · FY2022 · AI · contact PI
Intestinal allograft tolerance in large animals$692,145
R01 · FY2022 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$549,975
P01 · FY2022 · AI · contact PI
Lymphocyte reconstitution and responses in intestinal transplantation$368,000
P01 · FY2022 · AI · contact PI
Core-002$354,251
U19 · FY2022 · AI · contact PI
Training in Translational Immunology Research$309,832
T32 · FY2022 · AI · contact PI
Core-001$229,663
U19 · FY2022 · AI · contact PI
Cytometry & Cell Sorting Core$149,037
P30 · FY2022 · DK · contact PI
Admin-Core-001$93,411
U19 · FY2022 · AI · contact PI
Administrative and Data Management Core$81,811
P01 · FY2022 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$2,047,856
U19 · FY2021 · AI · contact PI
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems$951,710
U01 · FY2021 · DK · contact PI
Intestinal allograft tolerance in large animals$692,145
R01 · FY2021 · AI
Lymphocyte reconstitution and responses in intestinal transplantation$368,000
P01 · FY2021 · AI · contact PI
Training in Translational Immunology Research$307,373
T32 · FY2021 · AI · contact PI
Intestinal allograft tolerance in large animals$201,065
R01 · FY2021 · AI
Cytometry & Cell Sorting Core$149,040
P30 · FY2021 · DK · contact PI
Administrative Core$80,052
U19 · FY2021 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,121,671
P01 · FY2020 · AI · contact PI
CHARACTERIZING AND IMPROVING HUMANIZED IMMUNE SYSTEM MOUSE MODELS (IMM-HIS)$2,198,719
N01 · FY2020 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$2,047,856
U19 · FY2020 · AI · contact PI
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems$951,344
U01 · FY2020 · DK · contact PI
Intestinal allograft tolerance in large animals$692,145
R01 · FY2020 · AI
Tolerance of Adaptive and Innate Human Anti-pig Immune Responses in Humanized Mice$453,298
P01 · FY2020 · AI · contact PI
Lymphocyte reconstitution and responses in intestinal transplantation$368,000
P01 · FY2020 · AI · contact PI
Intestinal allograft tolerance in large animals$283,116
R01 · FY2020 · AI
Thymic negative selection in human T1D immune systems$198,073
R21 · FY2020 · AI · contact PI
Training in Translational Immunology Research$153,115
T32 · FY2020 · AI · contact PI
Administrative and Data Management Core$92,742
P01 · FY2020 · AI · contact PI
Administrative Core$80,000
U19 · FY2020 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,185,930
P01 · FY2019 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$2,047,856
U19 · FY2019 · AI · contact PI
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems$982,420
U01 · FY2019 · DK · contact PI
Robust allograft tolerance in non-human primates$789,995
R01 · FY2019 · OD · contact PI
Intestinal allograft tolerance in large animals$692,145
R01 · FY2019 · AI
Tolerance of Adaptive and Innate Human Anti-pig Immune Responses in Humanized Mice$517,557
P01 · FY2019 · AI · contact PI
Robust allograft tolerance in non-human primates$419,225
R01 · FY2019 · OD · contact PI
Lymphocyte reconstitution and responses in intestinal transplantation$370,898
P01 · FY2019 · AI · contact PI
Thymic negative selection in human T1D immune systems$238,702
R21 · FY2019 · AI · contact PI
TCR and BCR deep sequencing to distinguish autoimmune recurrence from allograft rejection$202,250
R21 · FY2019 · TR · contact PI
Cytometry & Cell Sorting Core$149,040
P30 · FY2019 · DK · contact PI
Administrative and Data Management Core$92,742
P01 · FY2019 · AI · contact PI
Administrative Core$80,000
U19 · FY2019 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,235,511
P01 · FY2018 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$2,382,512
U19 · FY2018 · AI · contact PI
Robust allograft tolerance in non-human primates$789,995
R01 · FY2018 · OD · contact PI
Intestinal allograft tolerance in large animals$688,585
R01 · FY2018 · AI
Tolerance of Adaptive and Innate Human Anti-pig Immune Responses in Humanized Mice$567,138
P01 · FY2018 · AI · contact PI
Immune Response to iPSC-Derived Beta Cells in Type 1 Diabetes$516,627
R01 · FY2018 · DK · contact PI
Lymphocyte reconstitution and responses in intestinal transplantation$368,000
P01 · FY2018 · AI · contact PI
TCR and BCR deep sequencing to distinguish autoimmune recurrence from allograft rejection$258,250
R21 · FY2018 · TR · contact PI
Cytometry & Cell Sorting Core$148,273
P30 · FY2018 · DK · contact PI
Administrative and Data Management Core$92,742
P01 · FY2018 · AI · contact PI
Administrative Core$80,528
U19 · FY2018 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-pig Immune Responses in Humanized Mice$49,581
P01 · FY2018 · AI · contact PI
A Tolerance Approach to Xenotransplantation$49,581
P01 · FY2018 · AI · contact PI
A Tolerance Approach to Xenotransplantation$3,166,671
P01 · FY2017 · AI · contact PI
Regulatory T cells to promote mixed chimerism for tolerance to islets and kidneys from deceased and living donors$2,098,315
U19 · FY2017 · AI · contact PI
Using Polyclonal Tregs to Develop a Compressed BMT Regiment for Deceased Donor Islets and Kidneys$756,169
U19 · FY2017 · AI · contact PI
Robust allograft tolerance in non-human primates$750,495
R01 · FY2017 · OD · contact PI
Immune Response to iPSC-Derived Beta Cells in Type 1 Diabetes$455,801
R01 · FY2017 · DK · contact PI
Tolerance of Adaptive and Innate Human Anti-pig Immune Responses in Humanized Mice$453,298
P01 · FY2017 · AI · contact PI
Lymphocyte Reconstitution and Responses in Intestinal Transplantation$436,800
P01 · FY2017 · AI · contact PI
Robust allograft tolerance in non-human primates$178,603
R01 · FY2017 · OD · contact PI
Core G: Flow Cytometry Core$168,497
P30 · FY2017 · DK · contact PI
Administrative and Data Management Core$92,742
P01 · FY2017 · AI · contact PI
Administrative Core$80,000
U19 · FY2017 · AI · contact PI
A Tolerance Approach to Xenotransplantation$2,745,913
P01 · FY2016 · AI · contact PI
Robust allograft tolerance in non-human primates$789,995
R01 · FY2016 · OD · contact PI
Lymphocyte Reconstitution and Responses in Intestinal Transplantation$353,692
P01 · FY2016 · AI · contact PI
Immune Response to iPSC-Derived Beta Cells in Type 1 Diabetes$348,566
R01 · FY2016 · DK · contact PI
Immune response to combined liver and bone marrow transplant for tolerance in NHP$320,000
R56 · FY2016 · AI · contact PI
Tolerance of Adaptive and Innate Human Anti-Pig Immune Responses in Humanized Mice$318,563
P01 · FY2016 · AI · contact PI
Immune Response to iPSC-Derived Beta Cells in Type 1 Diabetes$107,235
R01 · FY2016 · DK · contact PI
Administrative and Data Management Core$91,632
P01 · FY2016 · AI · contact PI
A Tolerance Approach to Xenotransplantation$2,938,083
P01 · FY2015 · AI
Robust allograft tolerance in non-human primates$783,995
R01 · FY2015 · OD · contact PI
Immune response to iPSC-derived beta cells in Type 1 diabetes$348,566
R01 · FY2015 · DK · contact PI
Lymphocyte Reconstitution and Responses in Intestinal Transplantation$348,330
P01 · FY2015 · AI · contact PI
Mixed Pig-Human Chimerism in a Humanized Mouse Model$286,049
P01 · FY2015 · AI · contact PI
Mice with autologous human T1D-derived immune systems and iPSC-derived beta cells$3,750,944
UC4 · FY2014 · DK · contact PI
A Tolerance Approach to Xenotransplantation$2,938,062
P01 · FY2014 · AI
Pig to human thymic xenotransplantation$489,776
R01 · FY2014 · AI · contact PI
Lymphocyte Reconstitution and Responses in Intestinal Transplantation$445,190
P01 · FY2014 · AI · contact PI
Mixed Pig-Human Chimerism in a Humanized Mouse Model$307,862
P01 · FY2014 · AI · contact PI
Pig to human thymic xenotransplantation$460,389
R01 · FY2013 · AI · contact PI
Anibody Tolerance by Mixed Chimerism Induction$454,183
P01 · FY2013 · HL · contact PI
Mixed Pig-Human Chimerism in a Humanized Mouse Model$411,222
P01 · FY2013 · AI · contact PI
Lymphocyte Reconstitution and Responses in Intestinal Transplantation$356,279
P01 · FY2013 · AI · contact PI
Pig to human thymic xenotransplantation$489,776
R01 · FY2012 · AI · contact PI
Anibody Tolerance by Mixed Chimerism Induction$477,014
P01 · FY2012 · HL · contact PI
Mixed Pig-Human Chimerism in a Humanized Mouse Model$460,403
P01 · FY2012 · AI · contact PI
Pig to human thymic xenotransplantation$503,346
R01 · FY2011 · AI · contact PI
Anibody Tolerance by Mixed Chimerism Induction$480,465
P01 · FY2011 · HL · contact PI
Mixed Pig-Human Chimerism in a Humanized Mouse Model$459,588
P01 · FY2011 · AI · contact PI
GVL without GVHD across HLA barriers: Translational Studies$1,927,639
P01 · FY2010 · CA · contact PI
Pig to human thymic xenotransplantation$508,923
R01 · FY2010 · AI · contact PI
Anibody Tolerance by Mixed Chimerism Induction$483,125
P01 · FY2010 · HL · contact PI
Mechanisms of tolerance in recipients of combined kidney and bone marrow transpla$420,126
R01 · FY2010 · AI · contact PI
IMMUNOBIOLOGY OF LYMPHOHEMATOPOIETIC GVH REACTIONS$400,875
P01 · FY2010 · CA · contact PI
In Vivo Delivery of siRNAs as a Novel Approach to Inducing Mixed Chimerism$262,915
R21 · FY2010 · HL · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$231,500
R01 · FY2010 · HL · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$209,532
R01 · FY2010 · HL · contact PI
GVL without GVHD across HLA barriers: Translational Studies$1,902,623
P01 · FY2009 · CA · contact PI
Anibody Tolerance by Mixed Chimerism Induction$487,278
P01 · FY2009 · HL · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$465,485
R01 · FY2009 · HL · contact PI
IMMUNOBIOLOGY OF LYMPHOHEMATOPOIETIC GVH REACTIONS$397,174
P01 · FY2009 · CA · contact PI
Porcine Thymic Transplantation to Mice with Human Immune Systems$329,701
P01 · FY2009 · AI · contact PI
In Vivo Delivery of siRNAs as a Novel Approach to Inducing Mixed Chimerism$240,691
R21 · FY2009 · HL · contact PI
Mechanisms of tolerance in recipients of combined kidney and bone marrow transpla$234,083
R01 · FY2009 · AI · contact PI
Mechanisms of tolerance in recipients of combined kidney and bone marrow transpla$207,999
R01 · FY2009 · AI · contact PI
GVL without GVHD across HLA barriers: Translational Studies$104,905
P01 · FY2009 · CA · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$24,640
R01 · FY2009 · HL · contact PI
GVL without GVHD across HLA barriers: Translational Studies$1,859,788
P01 · FY2008 · CA · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$438,059
R01 · FY2008 · HL · contact PI
IMMUNOBIOLOGY OF LYMPHOHEMATOPOIETIC GVH REACTIONS$345,813
P01 · FY2008 · CA · contact PI
Porcine Thymic Transplantation to Mice with Human Immune Systems$322,031
P01 · FY2008 · AI · contact PI
Separation of GVH and GVL in Mouse Models$261,354
R01 · FY2008 · CA · contact PI
Training in Transplantation Biology$243,600
T32 · FY2008 · AI · contact PI
GVL without GVHD across HLA barriers: Translational Studies$1,884,598
P01 · FY2007 · CA · contact PI
T and B cell tolerance in presensitized mice$521,103
P01 · FY2007 · HL · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$461,850
R01 · FY2007 · HL · contact PI
IMMUNOBIOLOGY OF LYMPHOHEMATOPOIETIC GVH REACTIONS$396,361
P01 · FY2007 · CA · contact PI
Porcine Thymic Transplantation to Mice with Human Immune Systems$262,712
P01 · FY2007 · AI · contact PI
Separation of GVH and GVL in Mouse Models$261,354
R01 · FY2007 · CA · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$24,499
R01 · FY2007 · HL · contact PI
GVL without GVHD across HLA barriers: Translational Studies$1,607,304
P01 · FY2006 · CA · contact PI
T and B cell tolerance in presensitized mice$418,796
P01 · FY2006 · HL · contact PI
Mixed Chimerism Approach to Transplantation Tolerance$377,644
R01 · FY2006 · HL · contact PI
Porcine Thymic Transplantation to Mice with Human Immune Systems$322,708
P01 · FY2006 · AI · contact PI
Separation of GVH and GVL in Mouse Models$269,160
R01 · FY2006 · CA · contact PI
IMMUNOBIOLOGY OF LYMPHOHEMATOPOIETIC GVH REACTIONS$175,336
P01 · FY2006 · CA · contact PI
T and B cell tolerance in presensitized mice$394,150
P01 · FY2005 · HL
Separation of GVH and GVL in Mouse Models$275,637
R01 · FY2005 · CA
Porcine Thymic Transplantation to Mice with Human Immune Systems$159,404
P01 · FY2005 · AI
XENOGENEIC STEM CELL AND THYMIC REPLACEMENT IN AIDS$69,059
P51 · FY2005 · RR
Xenogeneic Stem Cell and Thymic Replacement in AIDS$963,510
P01 · FY2004 · AI
T and B cell tolerance in presensitized mice$384,781
P01 · FY2004 · HL
MIXED CHIMERISM AS AN APPROACH TO TRANSPLANT TOLERANCE$324,100
R01 · FY2004 · HL
Separation of GVH and GVL in Mouse Models$274,907
R01 · FY2004 · CA
XENOGENEIC STEM CELL AND THYMIC REPLACEMENT IN AIDS$64,424
P51 · FY2004 · RR
Xenogeneic Stem Cell and Thymic Replacement in AIDS$935,446
P01 · FY2003 · AI
T and B cell tolerance in presensitized mice$373,573
P01 · FY2003 · HL
MIXED CHIMERISM AS AN APPROACH TO TRANSPLANT TOLERANCE$324,100
R01 · FY2003 · HL
T AND B CELL TOLERANCE IN HUMAN MIXED CHIMERAS$303,522
R01 · FY2003 · HL
SEPARATION OF GVH AND GVL IN MOUSE MODELS$221,230
R01 · FY2003 · CA
T and B Cell Tolerance via Marrow Transplantation$104,206
R01 · FY2003 · AI
Xenogeneic Stem Cell and Thymic Replacement in AIDS$848,198
P01 · FY2002 · AI
COMPATIBILITY OF SWINE STEM CELLS AND HUMAN STROMA$331,187
R01 · FY2002 · HL
MIXED CHIMERISM AS AN APPROACH TO TRANSPLANT TOLERANCE$324,100
R01 · FY2002 · HL
T AND B CELL TOLERANCE IN HUMAN MIXED CHIMERAS$296,075
R01 · FY2002 · HL
MURINE STUDIES OF XENOTRANSPLANTATION$256,338
P01 · FY2002 · AI
SEPARATION OF GVH AND GVL IN MOUSE MODELS$214,784
R01 · FY2002 · CA
XENOGENIC TOLERANCE IN MICE$205,924
P01 · FY2002 · HL
Xenogeneic Stem Cell and Thymic Replacement in AIDS$900,000
P01 · FY2001 · AI
COMPATIBILITY OF SWINE STEM CELLS AND HUMAN STROMA$324,615
R01 · FY2001 · HL
MIXED CHIMERISM AS AN APPROACH TO TRANSPLANT TOLERANCE$324,100
R01 · FY2001 · HL
T AND B CELL TOLERANCE IN HUMAN MIXED CHIMERAS$288,843
R01 · FY2001 · HL
MURINE STUDIES OF XENOTRANSPLANTATION$256,338
P01 · FY2001 · AI
SEPARATION OF GVH AND GVL IN MOUSE MODELS$208,529
R01 · FY2001 · CA
XENOGENIC TOLERANCE IN MICE$205,924
P01 · FY2001 · HL
XENOGENEIC STEM CELL AND THYMIC REPLACEMENT IN AIDS$769,013
P01 · FY2000 · AI
XENOGENIC TOLERANCE IN MICE$382,644
P01 · FY2000 · HL
MIXED CHIMERISM AS AN APPROACH TO TRANSPLANT TOLERANCE$323,250
R01 · FY2000 · HL
COMPATIBILITY OF SWINE STEM CELLS AND HUMAN STROMA$317,350
R01 · FY2000 · HL
T AND B CELL TOLERANCE IN HUMAN MIXED CHIMERAS$281,324
R01 · FY2000 · HL
MURINE STUDIES OF XENOTRANSPLANTATION$256,338
P01 · FY2000 · AI
SEPARATION OF GVH AND GVL IN MOUSE MODELS$202,454
R01 · FY2000 · CA