← Leaderboards
James J. Manfredi
Icahn School Of Medicine At Mount Sinai
$12,427,567
Attributed
$15,410,964
Total exposure
14
Grants
13
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$18,090,780 · 15
By mechanism
R01$12,736,290 · 5
P01$4,743,799 · 5
R56$286,179 · 1
R03$166,986 · 1
R29$149,026 · 1
R13$8,500 · 2
Top collaborators
- Carol Prives10 shared
Most similar at Icahn School Of Medicine At Mount Sinai
Same institution · by research overlap
- Carol Prives$28,176,184
- Indu A Ayappa$10,906,648
- Angela Diaz$9,604,054
- Jagat Narula$5,111,167
- Juan P Wisnivesky$34,328,417
Others in their field
Top investigators on “Tp53 Gene”
- Wei Gu · Columbia University Health Sciences$23,436,260
- Scott W Lowe · Sloan-Kettering Inst Can Research$18,601,564
- Xinbin Chen · Medical College Of Georgia (Mcg)$18,483,543
- Carol Prives · Icahn School Of Medicine At Mount Sinai$16,175,684
- Ronald Anthony Depinho · University Of Tx Md Anderson Can Ctr$13,177,214
- Guillermina Lozano · University Of Tx Md Anderson Can Ctr$13,000,456
Research focus
Tp53 GeneTumorTumor Suppressor ProteinsDna DamageGene ExpressionMolecularGenesInsightCellsIn VivoMalignant NeoplasmsResponseTumorigenesisProtein P53Transcriptional RegulationMouse ModelProteinsNeoplastic CellMutationBasePlayMediatingTumor SuppressionPhenotype
Grant awards (53)
Mutant p53 in Tumorigenesis, Invasion, and Metastasis$2,679,816
P01 · FY2025 · CA · contact PI
Cell lineage determinants of p53-driven fate outcomes in vivo$588,221
R01 · FY2025 · CA · contact PI
Mechanisms of transcriptional regulation by mutant p53$533,785
P01 · FY2025 · CA · contact PI
Administrative Core$172,657
P01 · FY2025 · CA · contact PI
Cell lineage determinants of p53-driven fate outcomes in vivo$558,809
R01 · FY2024 · CA · contact PI
Cell lineage determinants of p53-driven fate outcomes in vivo$576,456
R01 · FY2023 · CA · contact PI
Cell lineage determinants of p53-driven fate outcomes in vivo$576,567
R01 · FY2022 · CA · contact PI
Cell lineage determinants of p53-driven fate outcomes in vivo$667,823
R01 · FY2021 · CA · contact PI
Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesis$603,125
R01 · FY2020 · CA · contact PI
Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesis$596,041
R01 · FY2019 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$396,908
R01 · FY2019 · CA · contact PI
Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesis$623,302
R01 · FY2018 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$409,185
R01 · FY2018 · CA · contact PI
Modeling Mdm2- and 12q amplicon-driven sarcoma$83,493
R03 · FY2018 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$78,178
R01 · FY2018 · CA · contact PI
Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesis$559,746
R01 · FY2017 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$432,908
R01 · FY2017 · CA · contact PI
Modeling Mdm2- and 12q amplicon-driven sarcoma$83,493
R03 · FY2017 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$78,178
R01 · FY2017 · CA · contact PI
Role of the p53 C-terminal domain in tissue homeostasis, tumor suppression, and oncogenesis$616,704
R01 · FY2016 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$411,953
R01 · FY2016 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$78,178
R01 · FY2016 · CA · contact PI
Tissue-specific tumor suppressor effects of p53$400,089
R01 · FY2015 · CA · contact PI
Cell and Animal Model Core$153,680
P01 · FY2014 · CA · contact PI
Role of p53 in cell cycle checkpoints$320,693
R01 · FY2013 · CA · contact PI
Transcriptional regulation of apoptosis$258,428
R01 · FY2013 · CA · contact PI
Cell and Animal Model Core$151,269
P01 · FY2013 · CA · contact PI
The Seventh International Mdm2 Workshop$4,000
R13 · FY2013 · CA · contact PI
Role of p53 in cell cycle checkpoints$341,162
R01 · FY2012 · CA · contact PI
Transcriptional regulation of apoptosis$274,924
R01 · FY2012 · CA · contact PI
Cell and Animal Model Core$163,639
P01 · FY2012 · CA · contact PI
Role of p53 in cell cycle checkpoints$341,162
R01 · FY2011 · CA · contact PI
Transcriptional regulation of apoptosis$274,924
R01 · FY2011 · CA · contact PI
Cell and Animal Model Core$166,233
P01 · FY2011 · CA · contact PI
The Sixth International Mdm2 Workshop$4,500
R13 · FY2011 · CA · contact PI
Role of p53 in cell cycle checkpoints$351,713
R01 · FY2010 · CA · contact PI
Transcriptional regulation of apoptosis$283,426
R01 · FY2010 · CA · contact PI
Cell and Animal Model Core$90,918
P01 · FY2010 · CA · contact PI
Role of p53 in cell cycle checkpoints$351,713
R01 · FY2009 · CA · contact PI
Transcriptional regulation of apoptosis$283,426
R01 · FY2009 · CA · contact PI
Core--ANIMAL AND CELL MODEL$154,919
P01 · FY2009 · CA · contact PI
Core--ANIMAL AND CELL MODEL$150,404
P01 · FY2008 · CA · contact PI
Transcriptional regulation of apoptosis$286,179
R56 · FY2007 · CA · contact PI
Core--ANIMAL AND CELL MODEL$148,912
P01 · FY2007 · CA · contact PI
Determinants of cellular responses to p53$275,172
R01 · FY2006 · CA · contact PI
Core--ANIMAL AND CELL MODEL$90,096
P01 · FY2006 · CA · contact PI
Determinants of cellular responses to p53$281,794
R01 · FY2005 · CA
Core--ANIMAL AND CELL MODEL$87,471
P01 · FY2005 · CA
Determinants of cellular responses to p53$281,794
R01 · FY2004 · CA
Determinants of cellular responses to p53$281,794
R01 · FY2003 · CA
Determinants of cellular responses to p53$281,794
R01 · FY2002 · CA
MECHANISMS OF CARCINOGENESIS INVOLVING WILD-TYPE$22,035
R29 · FY2001 · CA
MECHANISMS OF CARCINOGENESIS INVOLVING WILD-TYPE$126,991
R29 · FY2000 · CA