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Laurence J Miller

Mayo Clinic Arizona

$18,092,149
Attributed
$20,379,206
Total exposure
8
Grants
8
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.5M · FY200525
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$20,379,206 · 8

By mechanism

R01$15,693,933 · 6
R37$4,530,893 · 1
R56$154,380 · 1

Top collaborators

Most similar at Mayo Clinic Arizona

Same institution · by research overlap

Others in their field

Top investigators on “Agonist

Research focus

AgonistReceptorG-Protein-Coupled ReceptorsPharmaceutical PreparationsDesignMolecularPeptidesSignal TransductionSmall MoleculeInsightLigandsSeriesLigand BindingStructureBiologicalAffectDrug DevelopmentBaseReceptor FunctionGrantReceptor BindingObesityReceptor Structure FunctionPhysiological

Grant awards (51)

Impact of membrane composition on cholecystokinin receptor structure and function$461,634
R01 · FY2025 · GM · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$454,632
R01 · FY2025 · HL · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$631,842
R01 · FY2024 · HL · contact PI
Impact of membrane composition on cholecystokinin receptor structure and function$461,634
R01 · FY2024 · GM · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$605,207
R01 · FY2023 · HL · contact PI
Impact of membrane composition on cholecystokinin receptor structure and function$461,634
R01 · FY2023 · GM · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$609,636
R01 · FY2022 · HL · contact PI
Impact of membrane composition on cholecystokinin receptor structure and function$478,133
R01 · FY2022 · GM · contact PI
Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor$372,298
R01 · FY2022 · GM · contact PI
Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor$372,298
R01 · FY2021 · GM · contact PI
Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity$415,000
R01 · FY2020 · DK · contact PI
Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor$372,298
R01 · FY2020 · GM · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$444,000
R01 · FY2019 · HL · contact PI
Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity$415,000
R01 · FY2019 · DK · contact PI
Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor$388,798
R01 · FY2019 · GM · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$451,250
R01 · FY2018 · HL · contact PI
Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity$415,000
R01 · FY2018 · DK · contact PI
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure$475,000
R01 · FY2017 · HL · contact PI
Type A CCK Receptor Structure, Function & Regulation$538,729
R01 · FY2014 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$154,380
R56 · FY2014 · DK · contact PI
Type A CCK Receptor Structure, Function & Regulation$519,872
R01 · FY2013 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$381,096
R01 · FY2013 · DK · contact PI
Type A CCK Receptor Structure, Function & Regulation$538,729
R01 · FY2012 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$412,779
R01 · FY2012 · DK · contact PI
Type A CCK Receptor Structure, Function & Regulation$545,758
R01 · FY2011 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$457,150
R01 · FY2011 · DK · contact PI
Type A CCK Receptor Structure Function and Regulation$490,426
R37 · FY2010 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$464,616
R01 · FY2010 · DK · contact PI
Secretin Receptor Structure, Function and Regulation$52,413
R01 · FY2010 · DK · contact PI
Type A CCK Receptor Structure Function and Regulation$484,490
R37 · FY2009 · DK · contact PI
Secretin Receptor Structure, Function, and Regulation$364,807
R01 · FY2009 · DK · contact PI
Secretin Receptor Structure, Function, and Regulation$14,270
R01 · FY2009 · DK · contact PI
Type A CCK Receptor Structure Function and Regulation$472,363
R37 · FY2008 · DK · contact PI
Secretin Receptor Structure, Function, and Regulation$354,240
R01 · FY2008 · DK · contact PI
Type A CCK Receptor Structure Function and Regulation$469,984
R37 · FY2007 · DK · contact PI
Secretin Receptor Structure, Function, and Regulation$350,995
R01 · FY2007 · DK · contact PI
Type A CCK Receptor Structure Function and Regulation$472,003
R37 · FY2006 · DK · contact PI
Secretin Receptor Structure, Function, and Regulation$351,009
R01 · FY2006 · DK · contact PI
Type A CCK Receptor Structure, Function and Regulation$454,015
R37 · FY2005 · DK
Secretin Receptor Structure, Function, and Regulation$349,049
R01 · FY2005 · DK
Type A CCK Receptor Structure, Function and Regulation$440,790
R37 · FY2004 · DK
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION$327,729
R01 · FY2004 · DK
Type A CCK Receptor Structure, Function and Regulation$427,951
R37 · FY2003 · DK
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION$318,184
R01 · FY2003 · DK
Type A CCK Receptor Structure, Function and Regulation$301,421
R37 · FY2002 · DK
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION$166,988
R01 · FY2002 · DK
Type A CCK Receptor Structure, Function and Regulation$114,066
R37 · FY2002 · DK
Type A CCK Receptor Structure, Function and Regulation$403,384
R37 · FY2001 · DK
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION$274,796
R01 · FY2001 · DK
TYPE A CCK RECEPTOR STRUCTURE, FUNCTION AND REGULATION$358,637
R01 · FY2000 · DK
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION$266,793
R01 · FY2000 · DK