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Daryl A Bosco

Univ Of Massachusetts Med Sch Worcester

$10,705,670
Attributed
$15,685,849
Total exposure
10
Grants
7
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.6M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$15,685,849 · 10

By mechanism

R01$11,172,862 · 5
RF1$3,323,710 · 1
R21$1,170,204 · 3
F32$19,073 · 1

Top collaborators

Most similar at Univ Of Massachusetts Med Sch Worcester

Same institution · by research overlap

Others in their field

Top investigators on “Amyotrophic Lateral Sclerosis

Research focus

Amyotrophic Lateral SclerosisMutantMutationProteinsNeurodegenerative DisordersMotor NeuronsPhenotypeGenesPathogenesisLinkCellsIn VitroPlayInheritedMediatingPathway InteractionsExhibitsInduced Pluripotent Stem CellAffectProteomicsDefectTissuesComplexNeurons

Grant awards (30)

Investigating aberrant vesicular degradation and lipid metabolism in neurodegeneration$3,323,710
RF1 · FY2025 · NS · contact PI
Investigating Dysfunction of Neuroimmune-Related Processes in Models of ALS/FTD TDP-43$251,250
R21 · FY2025 · NS · contact PI
Impact of ALS-linked mutations on the structure, dynamics and function of profilin-1$521,114
R01 · FY2024 · GM
Disruption of Nucleocytoplasmic Transport in FUS-related Neurodegenerative Diseases$776,944
R01 · FY2023 · NS · contact PI
Impact of ALS-linked mutations on the structure, dynamics and function of profilin-1$521,114
R01 · FY2023 · GM
Disruption of Nucleocytoplasmic Transport in FUS-related Neurodegenerative Diseases$790,424
R01 · FY2022 · NS · contact PI
Impact of ALS-linked mutations on the structure, dynamics and function of profilin-1$521,114
R01 · FY2022 · GM
Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases$806,490
R01 · FY2021 · NS · contact PI
Impact of ALS-linked mutations on the structure, dynamics and function of profilin-1$507,572
R01 · FY2021 · GM
Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases$86,783
R01 · FY2021 · NS · contact PI
Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases$814,945
R01 · FY2020 · NS · contact PI
Role of p38alpha signaling in mutant SOD1-linked motor neuron disease$458,329
R21 · FY2020 · NS
Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases$831,820
R01 · FY2019 · NS · contact PI
Misfolded ALS-linked Profilin-1: a novel therapeutic target$364,766
R01 · FY2018 · NS · contact PI
Misfolded ALS-linked Profilin-1: a novel therapeutic target$364,766
R01 · FY2017 · NS · contact PI
Misfolded ALS-linked Profilin-1: a novel therapeutic target$364,766
R01 · FY2016 · NS · contact PI
Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules$359,844
R01 · FY2016 · NS · contact PI
Investigating the response of FUS/TLS to excitotoxic insult$209,375
R21 · FY2016 · NS · contact PI
Misfolded ALS-linked Profilin-1: a novel therapeutic target$364,766
R01 · FY2015 · NS · contact PI
Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules$359,844
R01 · FY2015 · NS · contact PI
Investigating the response of FUS/TLS to excitotoxic insult$251,250
R21 · FY2015 · NS · contact PI
Misfolded ALS-linked Profilin-1: a novel therapeutic target$379,395
R01 · FY2014 · NS · contact PI
Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules$323,859
R01 · FY2014 · NS · contact PI
Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules$347,250
R01 · FY2013 · NS · contact PI
Investigation of post-translational modifications in WT SOD1 in sporadic ALS$340,304
R01 · FY2013 · NS · contact PI
Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules$359,844
R01 · FY2012 · NS · contact PI
Investigation of post-translational modifications in WT SOD1 in sporadic ALS$352,647
R01 · FY2012 · NS · contact PI
Investigation of post-translational modifications in WT SOD1 in sporadic ALS$352,647
R01 · FY2011 · NS · contact PI
Investigation of post-translational modifications in WT SOD1 in sporadic ALS$359,844
R01 · FY2010 · NS · contact PI
Oxidative metabolites in Alpha-Synucleinopathies$19,073
F32 · FY2005 · NS