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Roland Michael Tisch

Univ Of North Carolina Chapel Hill

$18,372,654
Attributed
$18,574,814
Total exposure
19
Grants
16
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.4M · FY200525
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$18,574,814 · 19

By mechanism

R01$14,177,679 · 10
R21$2,812,189 · 7
T32$1,395,019 · 1
P01$189,927 · 1

Top collaborators

Most similar at Univ Of North Carolina Chapel Hill

Same institution · by research overlap

Others in their field

Top investigators on “Autoimmunity

Research focus

AutoimmunityMediatingT-LymphocyteInsulin-Dependent Diabetes MellitusDiabetes MellitusInbred Nod MiceEventCellsCd8b1 GeneAutoimmune DiseasesAffectImmunotherapyInsightRegulatory T-LymphocyteIsletPreventTissuesBaseAntigen-Presenting CellsClinicPathologyDiabeticPathogenicityInsulin

Grant awards (61)

Regulation of T cell-mediated T1D: The role of T follicular helper cells$455,491
R01 · FY2025 · DK · contact PI
Enhancing antigen-based therapy for T1D by T cell coreceptor tuning$194,375
R21 · FY2024 · AI · contact PI
Thymic and peripheral regulation of autoreactive T cells by coreceptor therapy$388,750
R01 · FY2023 · AI · contact PI
Enhancing antigen-based therapy for T1D by T cell coreceptor tuning$233,250
R21 · FY2023 · AI · contact PI
The role of AIM2 in T cell-mediated autoimmunity$388,750
R01 · FY2022 · AI · contact PI
Thymic and peripheral regulation of autoreactive T cells by coreceptor therapy$388,750
R01 · FY2022 · AI · contact PI
Thymic and peripheral regulation of autoreactive T cells by coreceptor therapy$388,750
R01 · FY2021 · AI · contact PI
The role of AIM2 in T cell-mediated autoimmunity$388,750
R01 · FY2021 · AI · contact PI
ICES-based Pulsed Field Electromagnetic Field Therapy for Autoimmunity$194,375
R21 · FY2021 · AI · contact PI
Basic Immune Mechanisms$398,189
T32 · FY2020 · AI · contact PI
The role of AIM2 in T cell-mediated autoimmunity$388,750
R01 · FY2020 · AI · contact PI
Thymic and peripheral regulation of autoreactive T cells by coreceptor therapy$388,750
R01 · FY2020 · AI · contact PI
ICES-based Pulsed Field Electromagnetic Field Therapy for Autoimmunity$233,250
R21 · FY2020 · AI · contact PI
The role of AIM2 in T cell-mediated autoimmunity$388,750
R01 · FY2019 · AI · contact PI
Thymic and peripheral regulation of autoreactive T cells by coreceptor therapy$388,750
R01 · FY2019 · AI · contact PI
Basic Immune Mechanisms$375,823
T32 · FY2019 · AI · contact PI
AIM2 Function in Beta Cells and Type 1 Diabetes$194,375
R21 · FY2019 · AI · contact PI
Combinatorial Beta Cell-Specific Cytokine Therapy to Reverse Type I Diabetes$378,354
R01 · FY2018 · DK · contact PI
Islet-Specific Tolerance Induced by T Cell Co-Receptor Therapy in Type 1 Diabetes$332,531
R01 · FY2018 · DK · contact PI
Basic Immune Mechanisms$298,942
T32 · FY2018 · AI · contact PI
AIM2 Function in Beta Cells and Type 1 Diabetes$233,250
R21 · FY2018 · AI · contact PI
Combinatorial Beta Cell-Specific Cytokine Therapy to Reverse Type I Diabetes$378,354
R01 · FY2017 · DK · contact PI
Islet-Specific Tolerance Induced by T Cell Co-Receptor Therapy in Type 1 Diabetes$332,531
R01 · FY2017 · DK · contact PI
Basic Immune Mechanisms$322,065
T32 · FY2017 · AI · contact PI
Combinatorial Beta Cell-Specific Cytokine Therapy to Reverse Type I Diabetes$378,354
R01 · FY2016 · DK · contact PI
Islet-Specific Tolerance Induced by T Cell Co-Receptor Therapy in Type 1 Diabetes$332,531
R01 · FY2016 · DK · contact PI
Human CD8+ T Cell Tolerance by Nondepleting Humanized CD8-Specific Antibody$197,272
R21 · FY2016 · AI · contact PI
Combinatorial beta Cell-Specific Cytokine Therapy to Reverse Type I Diabetes$391,354
R01 · FY2015 · DK · contact PI
Islet-Specific Tolerance Induced by T Cell Co-Receptor Therapy in Type 1 Diabetes$332,531
R01 · FY2015 · DK · contact PI
Human CD8+ T Cell Tolerance by Nondepleting Humanized CD8-Specific Antibody$236,208
R21 · FY2015 · AI · contact PI
Age-Dependent Thymic Events and the Development of Autoimmune T Cells in NOD Mice$363,569
R01 · FY2014 · AI · contact PI
Islet-Specific Tolerance Induced by T Cell Co-Receptor Therapy in Type 1 Diabetes$332,531
R01 · FY2014 · DK · contact PI
Development of Human beta cell-specific AAV Vectors for Type I Diabetes$190,000
R21 · FY2014 · AI · contact PI
Age-Dependent Thymic Events and the Development of Autoimmune T Cells in NOD Mice$341,754
R01 · FY2013 · AI · contact PI
Development of Human beta cell-specific AAV Vectors for Type I Diabetes$214,320
R21 · FY2013 · AI · contact PI
A Novel Approach of beta Cell Replacement to Reverse Type I Diabetes in NOD Mice$181,757
R21 · FY2013 · AI · contact PI
Age-Dependent Thymic Events and the Development of Autoimmune T Cells in NOD Mice$363,569
R01 · FY2012 · AI · contact PI
Reversal of Type I Diabetes in NOD Mice$288,518
R01 · FY2012 · DK · contact PI
A Novel Approach of beta Cell Replacement to Reverse Type I Diabetes in NOD Mice$218,757
R21 · FY2012 · AI · contact PI
Age-Dependent Thymic Events and the Development of Autoimmune T Cells in NOD Mice$363,569
R01 · FY2011 · AI · contact PI
Reversal of Type I Diabetes in NOD Mice$288,518
R01 · FY2011 · DK · contact PI
Age-Dependent Thymic Events and the Development of Autoimmune T Cells in NOD Mice$367,241
R01 · FY2010 · AI · contact PI
The Role of MerTK in Autoimmune Diabetes$342,633
R01 · FY2010 · AI · contact PI
Reversal of Type I Diabetes in NOD Mice$291,432
R01 · FY2010 · DK · contact PI
The Role of MerTK in Autoimmune Diabetes$346,094
R01 · FY2009 · AI · contact PI
Reversal of Type I Diabetes in NOD Mice$294,214
R01 · FY2009 · DK · contact PI
The Role of MerTK in Autoimmune Diabetes$125,159
R01 · FY2009 · AI · contact PI
The Role of MerTK in Autoimmune Diabetes$346,094
R01 · FY2008 · AI · contact PI
Defining Antigen Induced Immunoregulation in T1 Diabetes$338,790
R01 · FY2008 · AI · contact PI
The Role of MerTK in Autoimmune Diabetes$352,796
R01 · FY2007 · AI · contact PI
Defining Antigen Induced Immunoregulation in T1 Diabetes$345,353
R01 · FY2007 · AI · contact PI
The Role of MerTK in Autoimmune Diabetes$363,333
R01 · FY2006 · AI · contact PI
Defining Antigen Induced Immunoregulation in T1 Diabetes$355,668
R01 · FY2006 · AI · contact PI
Defining Antigen Induced Immunoregulation in T1 Diabetes$364,228
R01 · FY2005 · AI
Defining Antigen Induced Immunoregulation in T1 Diabetes$358,335
R01 · FY2004 · AI
The Use of VEE Replicons Encoding GAD65 to Treat IDDM$145,500
R21 · FY2002 · AI
T CELL REACTIVITY TO GAD65 IN DIABETES$144,500
R01 · FY2002 · DK
The Use of VEE Replicons Encoding GAD65 to Treat IDDM$145,500
R21 · FY2001 · AI
T CELL REACTIVITY TO GAD65 IN DIABETES$144,500
R01 · FY2001 · DK
ANTIGEN SPECIFIC IMMUNE DEVIATION TO PROTECT ISLET GRAFTS$189,927
P01 · FY2000 · AI
T CELL REACTIVITY TO GAD65 IN DIABETES$144,500
R01 · FY2000 · DK