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Luis J. Sigal

Thomas Jefferson University

$24,916,604
Attributed
$27,743,182
Total exposure
18
Grants
15
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.9M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$37,323,639 · 19

By mechanism

R01$19,466,680 · 6
U19$12,627,210 · 4
R21$2,694,617 · 6
T32$1,093,466 · 1
R56$1,043,341 · 1
P30$398,325 · 1

Most similar at Thomas Jefferson University

Same institution · by research overlap

Others in their field

Top investigators on “Virus Diseases

Research focus

Virus DiseasesVirusMouse Pox VirusCellsInfectionViralResponseInterferonsAffectImmune ResponseOrthopoxvirusPathogenBone MarrowIn VivoSignal TransductionInfectious EctromeliaCell TypeResistanceProductionT-LymphocyteImmuneProgramsVaccinesGenes

Grant awards (84)

Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$817,205
R01 · FY2025 · AI
Mechanisms of protective memory CD8 T-cell induction by mRNA-LNP vaccines$708,737
R01 · FY2025 · AI · contact PI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$49,163
R01 · FY2025 · AI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$848,303
R01 · FY2024 · AI
Mechanisms of protective memory CD8 T-cell induction by mRNA-LNP vaccines$708,737
R01 · FY2024 · AI · contact PI
Skin-homing Group-1 innate lymphoid cells in viral defense$195,000
R21 · FY2024 · AI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$147,486
R01 · FY2024 · AI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$848,303
R01 · FY2023 · AI
Mechanisms of protective memory CD8 T-cell induction by mRNA-LNP vaccines$722,737
R01 · FY2023 · AI · contact PI
Skin-homing Group-1 innate lymphoid cells in viral defense$234,000
R21 · FY2023 · AI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$98,324
R01 · FY2023 · AI
Mapping spatiotemporal dynamics during enterovirus infection across cells and tissues$868,678
R01 · FY2022 · AI
Discovering new genes involved in monocyte-mediated protective anti-viral innate immunity through the generation of mice with targeted mutations$195,000
R21 · FY2022 · AI · contact PI
Training grant on Vaccines and Immunotherapies for Infectious Diseases and Cancer$164,930
T32 · FY2022 · AI · contact PI
Laboratory Animals$132,775
P30 · FY2022 · CA · contact PI
IFN-I production in vivo for resistance to acute disseminating viral Infections$437,417
R56 · FY2021 · AI · contact PI
Discovering new genes involved in monocyte-mediated protective anti-viral innate immunity through the generation of mice with targeted mutations$234,000
R21 · FY2021 · AI · contact PI
Training grant on Vaccines and Immunotherapies for Infectious Diseases and Cancer$223,821
T32 · FY2021 · AI · contact PI
Discovering new genes involved in protective T-cell responses through the generation of mice with targeted mutations$195,000
R21 · FY2021 · AI · contact PI
Laboratory Animals$132,775
P30 · FY2021 · CA · contact PI
Discovering new genes involved in protective T-cell responses through the generation of mice with targeted mutations$234,000
R21 · FY2020 · AI · contact PI
Training grant on Vaccines and Immunotherapies for Infectious Diseases and Cancer$222,539
T32 · FY2020 · AI · contact PI
Laboratory Animals$132,775
P30 · FY2020 · CA · contact PI
Inflammatory monocytes in the draining lymph node of ECTV infected mice$520,730
R01 · FY2019 · AI · contact PI
Training grant on Vaccines and Immunotherapies for Infectious Diseases and Cancer$244,397
T32 · FY2019 · AI · contact PI
Inflammatory monocytes in the draining lymph node of ECTV infected mice$529,409
R01 · FY2018 · AI · contact PI
Natural Killer Cell Deficiencies in Aging Mice$351,000
R01 · FY2018 · AG · contact PI
Training grant on Vaccines and Immunotherapies for Infectious Diseases and Cancer$237,779
T32 · FY2018 · AI · contact PI
Inflammatory monocytes in the draining lymph node of ECTV infected mice$520,730
R01 · FY2017 · AI · contact PI
Natural Killer Cell Deficiencies in Aging Mice$351,000
R01 · FY2017 · AG · contact PI
Inflammatory monocytes in the draining lymph node of ECTV infected mice$522,789
R01 · FY2016 · AI · contact PI
Mechanisms of NK Cell Migration to the Draining Lymph Node in Viral Infections$505,796
R01 · FY2016 · AI · contact PI
Natural Killer Cell Deficiencies in Aging Mice$351,000
R01 · FY2016 · AG · contact PI
Mechanisms of NK Cell Migration to the Draining Lymph Node in Viral Infections$578,747
R01 · FY2015 · AI · contact PI
Natural Killer Cell Deficiencies in Aging Mice$389,576
R01 · FY2015 · AG · contact PI
Inflammatory monocytes in the draining lymph node of ECTV infected mice$197,216
R01 · FY2015 · AI · contact PI
The Immune Response to Ectromelia Virus in the Draining Lymph Node$605,924
R56 · FY2014 · AI · contact PI
Mechanisms of NK Cell Migration to the Draining Lymph Node in Viral Infections$578,747
R01 · FY2014 · AI · contact PI
Natural Killer Cell Deficiencies in Aging Mice$401,625
R01 · FY2014 · AG · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$1,662,311
U19 · FY2013 · AI · contact PI
Mechanisms of NK Cell Migration to the Draining Lymph Node in Viral Infections$544,023
R01 · FY2013 · AI · contact PI
Mechanisms of Natural and Acquired Resistance to mousepox$442,121
U19 · FY2013 · AI · contact PI
Small Molecule Inhibitors of the Poxvirus Type I Interferon Binding Protein$209,738
R21 · FY2013 · AI · contact PI
Administrative Core$48,408
U19 · FY2013 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$1,779,931
U19 · FY2012 · AI · contact PI
Mechanisms of NK Cell Migration to the Draining Lymph Node in Viral Infections$589,396
R01 · FY2012 · AI · contact PI
Mechanisms of Natural and Acquired Resistance to mousepox$460,040
U19 · FY2012 · AI · contact PI
Small Molecule Inhibitors of the Poxvirus Type I Interferon Binding Protein$243,490
R21 · FY2012 · AI · contact PI
Administrative Core$38,257
U19 · FY2012 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$1,990,501
U19 · FY2011 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$419,446
R01 · FY2011 · AI · contact PI
Mechanisms of Natural and Acquired Resistance to mousepox$394,987
U19 · FY2011 · AI · contact PI
Bioreagents Core$187,932
U19 · FY2011 · AI · contact PI
Administrative Core$127,172
U19 · FY2011 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$2,014,562
U19 · FY2010 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$600,111
R01 · FY2010 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$423,683
R01 · FY2010 · AI · contact PI
Mechanisms of Natural and Acquired Resistance to mousepox$398,143
U19 · FY2010 · AI · contact PI
Bioreagents Core$190,807
U19 · FY2010 · AI · contact PI
Administrative Core$128,069
U19 · FY2010 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$99,064
U19 · FY2010 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$21,331
R01 · FY2010 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$10,665
R01 · FY2010 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$1,935,772
U19 · FY2009 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$576,711
R01 · FY2009 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$419,378
R01 · FY2009 · AI · contact PI
Mechanisms of Natural and Acquired Resistance to mousepox$352,127
U19 · FY2009 · AI · contact PI
Bioreagents Core$155,507
U19 · FY2009 · AI · contact PI
Administrative Core$123,183
U19 · FY2009 · AI · contact PI
Immune Mechanisms That Control Ectromelia Virus Infection$98,316
U19 · FY2009 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$559,917
R01 · FY2008 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$419,378
R01 · FY2008 · AI · contact PI
Mousepox in Aged Mice$209,689
R21 · FY2008 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$554,137
R01 · FY2007 · AI · contact PI
MHC Class I Antigen Presentation in Viral Infections$427,500
R01 · FY2007 · AI · contact PI
Mousepox in Aged Mice$256,500
R21 · FY2007 · AI · contact PI
Orthropoxvirus Pathogenesis and Vaccines$597,016
R01 · FY2006 · AI · contact PI
Cross-Presentation in CTL Responses to Viral Infections$341,000
R01 · FY2005 · AI
Identification of Genes Involved in Cross-Presentation$253,500
R21 · FY2005 · AI
Cross-Presentation in CTL Responses to Viral Infections$341,000
R01 · FY2004 · AI
Identification of Genes Involved in Cross-Presentation$234,700
R21 · FY2004 · AI
Cross-Presentation in CTL Responses to Viral Infections$341,000
R01 · FY2003 · AI
Cross-Presentation in CTL Responses to Viral Infections$341,000
R01 · FY2002 · AI
Cross-Presentation in CTL Responses to Viral Infections$323,950
R01 · FY2001 · AI